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Open AccessJournal ArticleDOI

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

TLDR
This is the first study providing evidence for Zika virus infection causing Guillain-Barré syndrome, and because Zika virus is spreading rapidly across the Americas, at risk countries need to prepare for adequate intensive care beds capacity to manage patients with Guillay-B Barré syndrome.
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This article is published in The Lancet.The article was published on 2016-04-09 and is currently open access. It has received 1925 citations till now. The article focuses on the topics: Zika virus & Zika virus disease.

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The Asian Lineage of Zika Virus: Transmission and Evolution in Asia and the Americas

TL;DR: This review critically appraise the recent advances in molecular epidemiological studies of ZIKV performed to date and highlights the pivotal role played by genomic surveillance in elucidating the origins, dissemination and evolution of the Asian lineage of ZikV in Asia and in the Americas.
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Novel pathomechanisms in inflammatory neuropathies

TL;DR: Current understanding of antigenic targets and the relevance of new immunological concepts for inflammatory neuropathies are summarized and the gap between pre-clinical and clinical findings is illustrated and future directions of development are outlined.
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A localized surface plasmon resonance-amplified immunofluorescence biosensor for ultrasensitive and rapid detection of nonstructural protein 1 of Zika virus.

TL;DR: A new immunofluorescence biosensor for the detection of nonstructural protein 1 (NS1) of the ZIKV is reported, which operates using the localized surface plasmon resonance (LSPR) signal from Plasmonic gold nanoparticles (AuNPs) to amplify the fluorescence intensity signal of quantum dots (QDs) within an antigen-antibody detection process.
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The Diversification of Zika Virus: Are There Two Distinct Lineages?

TL;DR: A phylogenetic tree of ZikV is reconstructed using the method based on shared amino acid replacements and it is found that ZIKV evolved into two distinct lineages, which supports the conventional phylogenetic divergence pattern of ZikaV.
References
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Zika virus outbreak on Yap Island, Federated States of Micronesia.

TL;DR: This outbreak of Zika virus illness in Micronesia represents transmission of Zikairus outside Africa and Asia and clinicians and public health officials should be aware of the risk of further expansion of Zika viruses transmission.
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Zika Virus (I). Isolations and serological specificity

TL;DR: Cross neutralization tests indicate that Zika virus is not related to yellow fever, Hawaii dengue nor to the FA and GD VII strains of Theiler's mouse encephalomyelitis virus.
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Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007

TL;DR: The full coding region nucleic acid sequence and serologic properties of the virus were identified and the virus was identified as Crimean-Congo-Wales coronavirus.
Journal Article

[Guillain-Barré syndrome].

TL;DR: High-dose of intravenous immunoglobulin (0.4 g/kg daily for 5 days) and PE are equally effective in intermediate and severe forms and the choice between the two treatments depends on their respective contra-indications and local availability.
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First report of autochthonous transmission of Zika virus in Brazil

TL;DR: Phylogenetic analysis suggests that the ZikV identified belongs to the Asian clade, the first report of ZIKV infection in Brazil, and the result was confirmed by DNA sequencing.
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