Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study
Van-Mai Cao-Lormeau,Alexandre Blake,Sandrine Mons,Stéphane Lastère,Claudine Roche,Jessica Vanhomwegen,Timothée Dub,Laure Baudouin,Anita Teissier,P. Larre,Anne-Laure Vial,Christophe Decam,Valérie Choumet,Susan K. Halstead,Hugh J. Willison,Lucile Musset,Jean-Claude Manuguerra,Philippe Desprès,Emmanuel Fournier,Henri-Pierre Mallet,Didier Musso,Arnaud Fontanet,Arnaud Fontanet,Jean Neil,Frédéric Ghawché +24 more
TLDR
This is the first study providing evidence for Zika virus infection causing Guillain-Barré syndrome, and because Zika virus is spreading rapidly across the Americas, at risk countries need to prepare for adequate intensive care beds capacity to manage patients with Guillay-B Barré syndrome.About:
This article is published in The Lancet.The article was published on 2016-04-09 and is currently open access. It has received 1925 citations till now. The article focuses on the topics: Zika virus & Zika virus disease.read more
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Humoral cross-reactivity between Zika and dengue viruses: implications for protection and pathology
TL;DR: The issue of humoral cross-reactivity between DENV and ZIKV is addressed, reviewing the evidence for and discussing the potential impact of this cross-recognition on the functional quality of antibody responses against ZikV, which is both timely and relevant to future vaccine design efforts.
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Guillain-Barré syndrome: causes, immunopathogenic mechanisms and treatment
Anil K. Jasti,Carlo Selmi,Juan Camilo Sarmiento-Monroy,Daniel A. Vega,Juan-Manuel Anaya,M. Eric Gershwin +5 more
TL;DR: The etiology and pathogenesis remain largely enigmatic and the syndrome results in death or severe disability in 9–17% of cases despite immunotherapy, but recent data point towards the role of ganglioside epitopes by immunohistochemical methods.
Journal ArticleDOI
Zika Virus Hijacks Stress Granule Proteins and Modulates the Host Stress Response
Shangmei Hou,Anil Kumar,Zaikun Xu,Adriana M. Airo,Iryna Stryapunina,Cheung Pang Wong,William G. Branton,Egor P. Tchesnokov,Matthias Götte,Christopher Power,Tom C. Hobman +10 more
TL;DR: It is shown that ZIKV induces the stress response through activation of the UPR (unfolded protein response) and PKR (protein kinase R), leading to host translational arrest, a process likely mediated by the viral proteins NS3 and NS4A.
Journal ArticleDOI
Smartphone-Based Mobile Detection Platform for Molecular Diagnostics and Spatiotemporal Disease Mapping.
Jinzhao Song,Vikram Pandian,Michael G. Mauk,Haim H. Bau,Sara Cherry,Laurence C. Tisi,Changchun Liu +6 more
TL;DR: A simple, inexpensive, hand-held, smartphone-based mobile detection platform, dubbed "smart-connected cup" (SCC), for rapid, connected, and quantitative molecular diagnostics, which demonstrates SCC's connectivity for disease spatiotemporal mapping with a custom-designed website.
Journal ArticleDOI
Public Health Emergencies of International Concern: A Historic Overview.
TL;DR: How public health emergencies of international concern (PHEIC) are formally declared, the diseases for which such declarations have been made from 2007 to 2020 and justifications for such declarations are reviewed.
References
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Mark R. Duffy,Tai-Ho Chen,W. Thane Hancock,Ann M. Powers,Jacob L. Kool,Robert S. Lanciotti,Moses Pretrick,Maria Marfel,Stacey Holzbauer,Christine Dubray,Laurent Guillaumot,Anne Griggs,Martin Bel,Amy J. Lambert,Janeen Laven,Olga I. Kosoy,Amanda J. Panella,Brad J. Biggerstaff,Marc Fischer,Edward B. Hayes +19 more
TL;DR: This outbreak of Zika virus illness in Micronesia represents transmission of Zikairus outside Africa and Asia and clinicians and public health officials should be aware of the risk of further expansion of Zika viruses transmission.
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Zika Virus (I). Isolations and serological specificity
TL;DR: Cross neutralization tests indicate that Zika virus is not related to yellow fever, Hawaii dengue nor to the FA and GD VII strains of Theiler's mouse encephalomyelitis virus.
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Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007
Robert S. Lanciotti,Olga Kosoy,Janeen Laven,Jason O. Velez,Amy J. Lambert,Alison J. Johnson,Stephanie M. Stanfield,Mark R. Duffy +7 more
TL;DR: The full coding region nucleic acid sequence and serologic properties of the virus were identified and the virus was identified as Crimean-Congo-Wales coronavirus.
Journal Article
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TL;DR: High-dose of intravenous immunoglobulin (0.4 g/kg daily for 5 days) and PE are equally effective in intermediate and severe forms and the choice between the two treatments depends on their respective contra-indications and local availability.
Journal ArticleDOI
First report of autochthonous transmission of Zika virus in Brazil
Camila Zanluca,Vanessa Campos Andrade de Melo,Ana Luiza Pamplona Mosimann,Glauco Igor Viana dos Santos,Claudia Nunes Duarte dos Santos,Kleber Giovanni Luz +5 more
TL;DR: Phylogenetic analysis suggests that the ZikV identified belongs to the Asian clade, the first report of ZIKV infection in Brazil, and the result was confirmed by DNA sequencing.
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