Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study
Van-Mai Cao-Lormeau,Alexandre Blake,Sandrine Mons,Stéphane Lastère,Claudine Roche,Jessica Vanhomwegen,Timothée Dub,Laure Baudouin,Anita Teissier,P. Larre,Anne-Laure Vial,Christophe Decam,Valérie Choumet,Susan K. Halstead,Hugh J. Willison,Lucile Musset,Jean-Claude Manuguerra,Philippe Desprès,Emmanuel Fournier,Henri-Pierre Mallet,Didier Musso,Arnaud Fontanet,Arnaud Fontanet,Jean Neil,Frédéric Ghawché +24 more
TLDR
This is the first study providing evidence for Zika virus infection causing Guillain-Barré syndrome, and because Zika virus is spreading rapidly across the Americas, at risk countries need to prepare for adequate intensive care beds capacity to manage patients with Guillay-B Barré syndrome.About:
This article is published in The Lancet.The article was published on 2016-04-09 and is currently open access. It has received 1925 citations till now. The article focuses on the topics: Zika virus & Zika virus disease.read more
Citations
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Recombinant Chimpanzee Adenovirus Vaccine AdC7-M/E Protects against Zika Virus Infection and Testis Damage
Kun Xu,Yufeng Song,Lianpan Dai,Yongli Zhang,Xuancheng Lu,Yijia Xie,Hangjie Zhang,Tao Cheng,Qihui Wang,Qingrui Huang,Yuhai Bi,William J. Liu,William J. Liu,Wenjun Liu,Xiangdong Li,Chuan Qin,Yi Shi,Jinghua Yan,Dongming Zhou,George F. Gao +19 more
TL;DR: Impressively, AdC7-M/E exhibited exceptional performance as a ZIKV vaccine, as follows: protective efficacy by a single vaccination, rapid development of a robust humoral response, durable immune responses, robust T cell responses, and sterilizing immunity achieved by asingle vaccination.
Journal ArticleDOI
Presence of Zika Virus in Conjunctival Fluid
TL;DR: The detection of ZikV from conjunctival swab samples of laboratory-confirmed ZIKV cases is described, which indicates that the virus is linked to microcephaly and Guillain-Barré syndrome.
Journal ArticleDOI
Advances in Diagnosis, Surveillance, and Monitoring of Zika Virus: An Update.
Raj Kumar Singh,Kuldeep Dhama,Kumaragurubaran Karthik,Ruchi Tiwari,Rekha Khandia,Ashok Munjal,Hafiz M.N. Iqbal,Yashpal Singh Malik,Rubén Bueno-Marí +8 more
TL;DR: New insights gained from the recent advances can aid in the rapid and definitive detection of this virus and/or Zika fever and will aid the strategies to design and adopt effective prevention and control strategies to counter this viral pathogen of great public health concern.
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Zika Vaccine Development: Current Status
TL;DR: It is clear that the world needs safe and effective vaccines to protect against Zika virus infection, but whether such vaccines can be developed through to licensure and public availability absent significant financial investment by countries, and other barriers discussed within this article, remains uncertain.
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Zika Virus as an Emerging Global Pathogen: Neurological Complications of Zika Virus
TL;DR: It is suggested that acute ZIKV infection in pregnant women may result in acute infection of fetal tissue and brain tissue, causing microcephaly and potentially severe debilitation of the infant or even death of the fetus.
References
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Journal ArticleDOI
Zika virus outbreak on Yap Island, Federated States of Micronesia.
Mark R. Duffy,Tai-Ho Chen,W. Thane Hancock,Ann M. Powers,Jacob L. Kool,Robert S. Lanciotti,Moses Pretrick,Maria Marfel,Stacey Holzbauer,Christine Dubray,Laurent Guillaumot,Anne Griggs,Martin Bel,Amy J. Lambert,Janeen Laven,Olga I. Kosoy,Amanda J. Panella,Brad J. Biggerstaff,Marc Fischer,Edward B. Hayes +19 more
TL;DR: This outbreak of Zika virus illness in Micronesia represents transmission of Zikairus outside Africa and Asia and clinicians and public health officials should be aware of the risk of further expansion of Zika viruses transmission.
Journal ArticleDOI
Zika Virus (I). Isolations and serological specificity
TL;DR: Cross neutralization tests indicate that Zika virus is not related to yellow fever, Hawaii dengue nor to the FA and GD VII strains of Theiler's mouse encephalomyelitis virus.
Journal ArticleDOI
Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007
Robert S. Lanciotti,Olga Kosoy,Janeen Laven,Jason O. Velez,Amy J. Lambert,Alison J. Johnson,Stephanie M. Stanfield,Mark R. Duffy +7 more
TL;DR: The full coding region nucleic acid sequence and serologic properties of the virus were identified and the virus was identified as Crimean-Congo-Wales coronavirus.
Journal Article
[Guillain-Barré syndrome].
TL;DR: High-dose of intravenous immunoglobulin (0.4 g/kg daily for 5 days) and PE are equally effective in intermediate and severe forms and the choice between the two treatments depends on their respective contra-indications and local availability.
Journal ArticleDOI
First report of autochthonous transmission of Zika virus in Brazil
Camila Zanluca,Vanessa Campos Andrade de Melo,Ana Luiza Pamplona Mosimann,Glauco Igor Viana dos Santos,Claudia Nunes Duarte dos Santos,Kleber Giovanni Luz +5 more
TL;DR: Phylogenetic analysis suggests that the ZikV identified belongs to the Asian clade, the first report of ZIKV infection in Brazil, and the result was confirmed by DNA sequencing.
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