Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study
Van-Mai Cao-Lormeau,Alexandre Blake,Sandrine Mons,Stéphane Lastère,Claudine Roche,Jessica Vanhomwegen,Timothée Dub,Laure Baudouin,Anita Teissier,P. Larre,Anne-Laure Vial,Christophe Decam,Valérie Choumet,Susan K. Halstead,Hugh J. Willison,Lucile Musset,Jean-Claude Manuguerra,Philippe Desprès,Emmanuel Fournier,Henri-Pierre Mallet,Didier Musso,Arnaud Fontanet,Arnaud Fontanet,Jean Neil,Frédéric Ghawché +24 more
TLDR
This is the first study providing evidence for Zika virus infection causing Guillain-Barré syndrome, and because Zika virus is spreading rapidly across the Americas, at risk countries need to prepare for adequate intensive care beds capacity to manage patients with Guillay-B Barré syndrome.About:
This article is published in The Lancet.The article was published on 2016-04-09 and is currently open access. It has received 1925 citations till now. The article focuses on the topics: Zika virus & Zika virus disease.read more
Citations
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Therapeutic Approaches for Zika Virus Infection of the Nervous System
TL;DR: An exhaustive review and compare each of the classes of drugs discovered, the methods used for drug discovery, and their potential use in humans for the prevention or treatment of neurological complications of Zika virus infection.
Journal ArticleDOI
Anticipating the Challenges of Zika Virus and the Incidence of Guillain-Barré Syndrome
Carl A. Gold,S. Andrew Josephson +1 more
TL;DR: A case-control study of patients who developed GBS during a Zika outbreak in French Polynesia provides evidence that Zika infection is the culprit and seeks to anticipate challenges that could face the health care system if the incidence of GBS were to sharply rise with the arrival of Zika.
Journal ArticleDOI
Dynamics of Zika Virus Model with Nonlinear Incidence and Optimal Control Strategies
TL;DR: The analysis based on the idea of optimal control theory made popular by Pontryagin’s principle is carried out, and the resulting optimality is quantitatively simulated to investigate the impact of the controls on the dynamics of Zika virus.
Journal ArticleDOI
Cell surface α2,3-linked sialic acid facilitates Zika virus internalization
Chee Wah Tan,Catherine Hong Huan Hor,Swee Sen Kwek,Han Kang Tee,I-Ching Sam,Eyleen L. K. Goh,Eng Eong Ooi,Yoke Fun Chan,Lin-Fa Wang +8 more
TL;DR: It is reported that cell surface sialic acid plays an important role in ZIKV infection and identification of α2,3-linked sialIC acid as an important host factor for ZikV internalization provides new insight into ZIKv infection and pathogenesis.
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Expression of a Zika virus antigen in microalgae: Towards mucosal vaccine development.
TL;DR: The algae-made ZK vaccine represents a promising candidate to formulate attractive vaccines against ZIKV and elicited significant humoral responses at a higher magnitude to those induced upon subcutaneous immunization.
References
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Journal ArticleDOI
Zika virus outbreak on Yap Island, Federated States of Micronesia.
Mark R. Duffy,Tai-Ho Chen,W. Thane Hancock,Ann M. Powers,Jacob L. Kool,Robert S. Lanciotti,Moses Pretrick,Maria Marfel,Stacey Holzbauer,Christine Dubray,Laurent Guillaumot,Anne Griggs,Martin Bel,Amy J. Lambert,Janeen Laven,Olga I. Kosoy,Amanda J. Panella,Brad J. Biggerstaff,Marc Fischer,Edward B. Hayes +19 more
TL;DR: This outbreak of Zika virus illness in Micronesia represents transmission of Zikairus outside Africa and Asia and clinicians and public health officials should be aware of the risk of further expansion of Zika viruses transmission.
Journal ArticleDOI
Zika Virus (I). Isolations and serological specificity
TL;DR: Cross neutralization tests indicate that Zika virus is not related to yellow fever, Hawaii dengue nor to the FA and GD VII strains of Theiler's mouse encephalomyelitis virus.
Journal ArticleDOI
Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007
Robert S. Lanciotti,Olga Kosoy,Janeen Laven,Jason O. Velez,Amy J. Lambert,Alison J. Johnson,Stephanie M. Stanfield,Mark R. Duffy +7 more
TL;DR: The full coding region nucleic acid sequence and serologic properties of the virus were identified and the virus was identified as Crimean-Congo-Wales coronavirus.
Journal Article
[Guillain-Barré syndrome].
TL;DR: High-dose of intravenous immunoglobulin (0.4 g/kg daily for 5 days) and PE are equally effective in intermediate and severe forms and the choice between the two treatments depends on their respective contra-indications and local availability.
Journal ArticleDOI
First report of autochthonous transmission of Zika virus in Brazil
Camila Zanluca,Vanessa Campos Andrade de Melo,Ana Luiza Pamplona Mosimann,Glauco Igor Viana dos Santos,Claudia Nunes Duarte dos Santos,Kleber Giovanni Luz +5 more
TL;DR: Phylogenetic analysis suggests that the ZikV identified belongs to the Asian clade, the first report of ZIKV infection in Brazil, and the result was confirmed by DNA sequencing.
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