Citations
More filters
Journal ArticleDOI
Structure and function study of the complex that synthesizes S-adenosylmethionine.
Ben Murray,Svetlana V. Antonyuk,Alberto Marina,Sebastiaan M. Van Liempd,Shelly C. Lu,José M. Mato,S. Samar Hasnain,Adriana L. Rojas +7 more
TL;DR: X-ray crystallography and solution X-ray scattering structures of the MAT2 complex show an unexpected stoichiometry, offering a unique mechanism of regulation and thus providing a gateway for structure-based drug design in anticancer therapies including liver disease.
Journal ArticleDOI
On high-resolution reciprocal-space mapping with a triple-crystal diffractometer for high-energy X-rays.
TL;DR: It is shown how the transverse and longitudinal resolution depend on the choice of the crystal reflection, and how the orientation of a reciprocal-lattice distortion in an investigated sample towards the resolution element of the instrument can play an important role.
Journal ArticleDOI
SnB version 2.2: an example of crystallographic multiprocessing
TL;DR: The computer program SnB implements a direct-methods algorithm, known as Shake-and-Bake, which optimizes trial structures consisting of randomly positioned atoms, which can be easily implemented in parallel in order to decrease the real time required to achieve a solution.
Journal ArticleDOI
TakeTwo: an indexing algorithm suited to still images with known crystal parameters
Helen M. Ginn,Philip Roedig,A. Kuo,Gwyndaf Evans,Nicholas K. Sauter,Oliver P. Ernst,Alke Meents,Henrike M. Mueller-Werkmeister,Henrike M. Mueller-Werkmeister,R.J.D. Miller,R.J.D. Miller,R.J.D. Miller,David I. Stuart +12 more
TL;DR: A novel indexing method is presented that is well suited to the minimal information on a still image diffraction pattern and can achieve indexing rates of over one lattice per image.
Journal ArticleDOI
UROX 2.0: an interactive tool for fitting atomic models into electron-microscopy reconstructions
Xavier Siebert,Jorge Navaza +1 more
TL;DR: UROX is software designed for the interactive fitting of atomic models into electron-microscopy reconstructions, and the main features of the software are presented.
References
More filters
Journal ArticleDOI
The Protein Data Bank
Helen M. Berman,John D. Westbrook,Zukang Feng,Gary L. Gilliland,Talapady N. Bhat,Helge Weissig,Ilya N. Shindyalov,Philip E. Bourne +7 more
TL;DR: The goals of the PDB are described, the systems in place for data deposition and access, how to obtain further information and plans for the future development of the resource are described.
Journal ArticleDOI
Crystal structure refinement with SHELXL
TL;DR: New features added to the refinement program SHELXL since 2008 are described and explained.
Journal ArticleDOI
Coot: model-building tools for molecular graphics.
Paul Emsley,Kevin Cowtan +1 more
TL;DR: CCP4mg is a project that aims to provide a general-purpose tool for structural biologists, providing tools for X-ray structure solution, structure comparison and analysis, and publication-quality graphics.
Journal ArticleDOI
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams,Paul D. Adams,Pavel V. Afonine,Gábor Bunkóczi,Vincent B. Chen,Ian W. Davis,Nathaniel Echols,Jeffrey J. Headd,Li-Wei Hung,Gary J. Kapral,Ralf W. Grosse-Kunstleve,Airlie J. McCoy,Nigel W. Moriarty,Robert D. Oeffner,Randy J. Read,David S. Richardson,Jane S. Richardson,Thomas C. Terwilliger,Peter H. Zwart +18 more
TL;DR: The PHENIX software for macromolecular structure determination is described and its uses and benefits are described.
Journal ArticleDOI
Phaser crystallographic software
Airlie J. McCoy,Ralf W. Grosse-Kunstleve,Paul D. Adams,Martyn Winn,Laurent C. Storoni,Randy J. Read +5 more
TL;DR: A description is given of Phaser-2.1: software for phasing macromolecular crystal structures by molecular replacement and single-wavelength anomalous dispersion phasing.