Citations
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Impact of synchrotron radiation on macromolecular crystallography: a personal view
TL;DR: The early history of the application of synchrotron radiation to structural biology, and particularly protein crystallography, is reviewed to show the tremendous impact that this experimental innovation has had on these disciplines.
Journal ArticleDOI
Structure of a Bacillus halmapalus family 13 α-amylase, BHA, in complex with an acarbose-derived nonasaccharide at 2.1 Å resolution
Gideon J. Davies,Andrzej M. Brzozowski,Zbigniew Dauter,Rasmussen,Torben Vedel Borchert,Keith S. Wilson +5 more
TL;DR: Careful inspection of electron density suggests that the bound ligand could not have been formed through successive transglycosylations of acarbose and must also have featured maltose or maltooligosaccharides as an acceptor.
Journal ArticleDOI
Raw diffraction data preservation and reuse: overview, update on practicalities and metadata requirements
TL;DR: There are rapid developments in storage options for the preservation and reuse of raw data within the scientific domain of the IUCr and its Commissions, each of which operates within a great diversity of instrumentation.
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In cellulo structure determination of a novel cypovirus polyhedrin
TL;DR: The crystal structure of a previously unsolved type of cypovirus polyhedrin has been determined from data collected directly from frozen live insect cells.
Journal ArticleDOI
Structure of LdtMt2, an l,d-transpeptidase from Mycobacterium tuberculosis
Dominic Böth,Eva Maria Steiner,Daniela Stadler,Ylva Lindqvist,Robert Schnell,Gunter Schneider +5 more
TL;DR: The crystal structures of two fragments of the l,d-transpeptidase from M. tuberculosis have been determined at 1.45 and 1.86 Å resolution.
References
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The Protein Data Bank
Helen M. Berman,John D. Westbrook,Zukang Feng,Gary L. Gilliland,Talapady N. Bhat,Helge Weissig,Ilya N. Shindyalov,Philip E. Bourne +7 more
TL;DR: The goals of the PDB are described, the systems in place for data deposition and access, how to obtain further information and plans for the future development of the resource are described.
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Crystal structure refinement with SHELXL
TL;DR: New features added to the refinement program SHELXL since 2008 are described and explained.
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Coot: model-building tools for molecular graphics.
Paul Emsley,Kevin Cowtan +1 more
TL;DR: CCP4mg is a project that aims to provide a general-purpose tool for structural biologists, providing tools for X-ray structure solution, structure comparison and analysis, and publication-quality graphics.
Journal ArticleDOI
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams,Paul D. Adams,Pavel V. Afonine,Gábor Bunkóczi,Vincent B. Chen,Ian W. Davis,Nathaniel Echols,Jeffrey J. Headd,Li-Wei Hung,Gary J. Kapral,Ralf W. Grosse-Kunstleve,Airlie J. McCoy,Nigel W. Moriarty,Robert D. Oeffner,Randy J. Read,David S. Richardson,Jane S. Richardson,Thomas C. Terwilliger,Peter H. Zwart +18 more
TL;DR: The PHENIX software for macromolecular structure determination is described and its uses and benefits are described.
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Phaser crystallographic software
Airlie J. McCoy,Ralf W. Grosse-Kunstleve,Paul D. Adams,Martyn Winn,Laurent C. Storoni,Randy J. Read +5 more
TL;DR: A description is given of Phaser-2.1: software for phasing macromolecular crystal structures by molecular replacement and single-wavelength anomalous dispersion phasing.