Journal ArticleDOI
Lipid changes of goat sperm plasma membrane during epididymal maturation
TLDR
The altered lipid profile of the mature sperm membrane leads to changes in its fluidity that play an important role in determining the structure and functions of the biomembrane.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1991-01-30. It has received 76 citations till now. The article focuses on the topics: Sperm plasma membrane & Membrane lipids.read more
Citations
More filters
Journal ArticleDOI
Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity
Jun-ichi Osuga,Shun Ishibashi,Teruaki Oka,Hiroaki Yagyu,Ryu-ichi Tozawa,Akihisa Fujimoto,Futoshi Shionoiri,Naoya Yahagi,Frederic B. Kraemer,Osamu Tsutsumi,Nobuhiro Yamada +10 more
TL;DR: It is shown that HSL is required for spermatogenesis but is not the only enzyme that mediates the hydrolysis of triacylglycerol stored in adipocytes, and that adipocytes were significantly enlarged and the size differences between cell and tissue suggests the heterogeneity of adipocytes.
Journal ArticleDOI
Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane
Frits M. Flesch,Jos F. Brouwers,Patricia F. E. M. Nievelstein,Arie J. Verkleij,Lambert M.G. van Golde,Ben Colenbrander,Barend M. Gadella +6 more
TL;DR: A model is proposed in which phospholipid scrambling induces the formation of an apical membrane raft in the sperm head surface that enables albumin mediated efflux of cholesterol.
Journal ArticleDOI
A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol.
Naomichi Okamura,Sachiko Kiuchi,Michiko Tamba,Takayuki Kashima,Shinsuke Hiramoto,Tadashi Baba,Françoise Dacheux,Jean-Louis Dacheux,Yoshiki Sugita,Yin-Zhe Jin +9 more
TL;DR: It was found that the He1 homolog is a major cholesterol-binding protein in the porcine epididymal fluid and the possibility that the HE1 homology is involved in the regulation of the lipid composition of the sperm membranes during the maturation in epidIDymis is discussed.
Journal ArticleDOI
The epididymis and sperm maturation: a perspective.
TL;DR: In common mammals, sperm leaving the testis are incapable of fertilizing a female gamete, and when assessing sperm maturation it is necessary to establish the proportion of sperm that has completed and retained all steps of maturation necessary to achieve fertilization of oocytes under the conditions imposed.
References
More filters
Journal ArticleDOI
Signal transduction via phosphatidylcholine cycles
Steven L. Pelech,Dennis E. Vance +1 more
TL;DR: Guanine nucleotide-binding proteins are implicated in the coupling of agonist receptors to the activation of phospholipases A 2, C and D, and stimulate the resynthesis of phosphatidylcholine via activation of CTP:phosphocholine cytidylyltransferase.
Journal ArticleDOI
A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.
TL;DR: It is demonstrated that TPA stimulates PC turnover in Madin-Darby canine kidney cells and provides evidence for a novel mechanism of diglyceride formation.
Journal ArticleDOI
Phosphatidylcholine breakdown in rat liver plasma membranes. Roles of guanine nucleotides and P2-purinergic agonists.
Helen Irving,J. H. Exton +1 more
TL;DR: Results indicate that a phosphatidylcholine phospholipase C is coupled to purinergic receptors in rat liver plasma membranes by a GTP-binding protein, which could contribute to hepatic diacylglycerol levels and thus influence protein kinase C activity.
Related Papers (5)
Development changes occurring in the lipids of ram epididymal spermatozoa plasma membrane.
John E. Parks,Roy H. Hammerstedt +1 more
Lipid composition and thermotropic phase behavior of boar, bull, stallion, and rooster sperm membranes.
John E. Parks,Daniel V. Lynch +1 more