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Open AccessJournal ArticleDOI

Medicinal mushroom: boon for therapeutic applications

TLDR
The present review focuses on the comprehensive account of the medicinal properties of various medicinal mushrooms, which will further help the researchers to understand the metabolites and find other metabolites from the mushrooms which can be used for the potential development of the drugs to treat various life-threatening diseases.
Abstract
Medicinal mushrooms are higher fungi with additional nutraceutical attributes having low fat content and a trans-isomer of unsaturated fatty acids along with high fibre content, triterpenes, phenolic compounds, sterols, eritadenine and chitosan. They are considered as the unmatched source of healthy foods and drugs. They have outstanding attractive taste, aroma and nutritional value, so are considered as functional food, which means they are beneficial to the body not only in terms of nutrition but also for improved health. Medicinal mushrooms and their extract have a large number of bioactive components called secondary metabolites. The presence of polysaccharide β-glucans or polysaccharide–protein complexes content in mushroom extract have great therapeutic applications in human health as they possess many properties such as anti-diabetic, anti-cancerous, anti-obesity, immunomodulatory, hypocholesteremia, hepatoprotective nature along with anti-aging. The present review focuses on the comprehensive account of the medicinal properties of various medicinal mushrooms. This will further help the researchers to understand the metabolites and find other metabolites as well from the mushrooms which can be used for the potential development of the drugs to treat various life-threatening diseases.

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Journal ArticleDOI

The biology of ergothioneine, an antioxidant nutraceutical.

TL;DR: Mushroom or ERG consumption seems to provide significant prevention against oxidative stress in a large variety of systems, and it may have value as a nutraceutical and antioxidant more generally.
Journal ArticleDOI

Current Prospects of Nutraceuticals: A Review.

TL;DR: An overview of various bioactive ingredients which act as nutraceuticals (carbohydrates, lipids, edible flowers, alkaloids, medicinal plants, etc.) and their role in health benefits has been discussed and further application of nutr pharmaceuticals in various diseases prevention has been also discussed.
Journal ArticleDOI

Molecular mechanistic insight of hepatitis B virus mediated hepatocellular carcinoma.

TL;DR: The molecular mechanisms that come from other than HBV endemic places which can be innovative approaches to treat HCC are outlined.
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Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products.

TL;DR: The current status of clinical studies on immunomodulatory activities of mushrooms and mushroom products are reviewed and the approaches that have been used in the development and application of bioactive compounds extracted from mushrooms are described.
Journal ArticleDOI

Edible Mushrooms as Functional Ingredients for Development of Healthier and More Sustainable Muscle Foods: A Flexitarian Approach.

TL;DR: In this article, the effects of functional ingredients of mushrooms in improving the quality and sensory attributes of nutritionally superior and next-generation healthier muscle food products are also highlighted in this paper.
References
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Journal ArticleDOI

A novel lectin with potent antitumor, mitogenic and HIV-1 reverse transcriptase inhibitory activities from the edible mushroom Pleurotus citrinopileatus.

TL;DR: The lectin exerted potent antitumor activity in mice bearing sarcoma 180, and caused approximately 80% inhibition of tumor growth when administered intraperitonealy at 5 mg/kg daily for 20 days and was devoid of antifungal activity.
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Fungi—an unusual source for cosmetics

TL;DR: This paper provides a review of the fungi presently used in cosmeceuticals and nutricosmetics with some examples of cosmetic types and products.
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Anti-diabetic activity present in the fruit body of Grifola frondosa (Maitake). I.

TL;DR: The fruit body of Grifola frondosa (maitake), Basidiomycetes was confirmed to contain substances with anti-diabetic activity and results suggest that the anti-Diabetic activity was present not only in the ES-fraction consisting of lipid but also in the X-fractions of peptidoglycan.
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Cyclooxygenase Inhibitory and Antioxidant Compounds from the Mycelia of the Edible Mushroom Grifola frondosa

TL;DR: The bioassay-guided isolation and purification of the hexane extract of the cultured mycelia of Grifola frondosa led to the characterization of a fatty acid fraction and three compounds, ergosterol, which were established by spectroscopic methods and showed cyclooxygenase (COX) enzyme inhibitory and antioxidant activities.
Journal ArticleDOI

Ganoderma lucidum extracts inhibit growth and induce actin polymerization in bladder cancer cells in vitro

TL;DR: Ethanol and water extracts of fruiting bodies and spores of the G. lucidum were used to examine growth inhibition, actin polymerization status, and impact of actin remodeling on cell migration and adhesion, and results showed that ethanol extracts had a stronger growth inhibition effect than water extracts.
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