scispace - formally typeset
Open AccessJournal ArticleDOI

Medicinal mushroom: boon for therapeutic applications

TLDR
The present review focuses on the comprehensive account of the medicinal properties of various medicinal mushrooms, which will further help the researchers to understand the metabolites and find other metabolites from the mushrooms which can be used for the potential development of the drugs to treat various life-threatening diseases.
Abstract
Medicinal mushrooms are higher fungi with additional nutraceutical attributes having low fat content and a trans-isomer of unsaturated fatty acids along with high fibre content, triterpenes, phenolic compounds, sterols, eritadenine and chitosan. They are considered as the unmatched source of healthy foods and drugs. They have outstanding attractive taste, aroma and nutritional value, so are considered as functional food, which means they are beneficial to the body not only in terms of nutrition but also for improved health. Medicinal mushrooms and their extract have a large number of bioactive components called secondary metabolites. The presence of polysaccharide β-glucans or polysaccharide–protein complexes content in mushroom extract have great therapeutic applications in human health as they possess many properties such as anti-diabetic, anti-cancerous, anti-obesity, immunomodulatory, hypocholesteremia, hepatoprotective nature along with anti-aging. The present review focuses on the comprehensive account of the medicinal properties of various medicinal mushrooms. This will further help the researchers to understand the metabolites and find other metabolites as well from the mushrooms which can be used for the potential development of the drugs to treat various life-threatening diseases.

read more

Content maybe subject to copyright    Report

Citations
More filters
Journal ArticleDOI

The biology of ergothioneine, an antioxidant nutraceutical.

TL;DR: Mushroom or ERG consumption seems to provide significant prevention against oxidative stress in a large variety of systems, and it may have value as a nutraceutical and antioxidant more generally.
Journal ArticleDOI

Current Prospects of Nutraceuticals: A Review.

TL;DR: An overview of various bioactive ingredients which act as nutraceuticals (carbohydrates, lipids, edible flowers, alkaloids, medicinal plants, etc.) and their role in health benefits has been discussed and further application of nutr pharmaceuticals in various diseases prevention has been also discussed.
Journal ArticleDOI

Molecular mechanistic insight of hepatitis B virus mediated hepatocellular carcinoma.

TL;DR: The molecular mechanisms that come from other than HBV endemic places which can be innovative approaches to treat HCC are outlined.
Journal ArticleDOI

Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products.

TL;DR: The current status of clinical studies on immunomodulatory activities of mushrooms and mushroom products are reviewed and the approaches that have been used in the development and application of bioactive compounds extracted from mushrooms are described.
Journal ArticleDOI

Edible Mushrooms as Functional Ingredients for Development of Healthier and More Sustainable Muscle Foods: A Flexitarian Approach.

TL;DR: In this article, the effects of functional ingredients of mushrooms in improving the quality and sensory attributes of nutritionally superior and next-generation healthier muscle food products are also highlighted in this paper.
References
More filters
Journal ArticleDOI

Dietary components may prevent mutation-related diseases in humans

TL;DR: Information is provided about the antimutagenic and anticarcinogenic potentials of some dietary constituents and foods widely consumed in Brazil to reinforce diet as a key factor in determining genomic stability and preventing human diseases.
Journal ArticleDOI

Anti-genotoxic effect of aqueous extracts of sun mushroom (Agaricus blazei Murill lineage 99/26) in mammalian cells in vitro.

TL;DR: The results obtained in the MN test showed that the three forms of extracts used had protective activity, suggesting that the compound or active ingredients of A. blazei are always present in these extracts, and suggests that the extracts have an antimutagenic action of the desmutagenic type.
Journal ArticleDOI

Selective induction of apoptosis in murine skin carcinoma cells (CH72) by an ethanol extract of Lentinula edodes.

TL;DR: In this article, the effects of ethanol extracts from four species of mushroom fruiting bodies, mushroom spores and mushroom cultured broth, were assessed for modulation of cell proliferation and apoptosis in murine skin carcinoma cells (CH72) and non-tumorigenic epidermal cells (C50).
Journal ArticleDOI

Extract of Pleurotus pulmonarius Suppresses Liver Cancer Development and Progression through Inhibition of VEGF-Induced PI3K/AKT Signaling Pathway

TL;DR: The results demonstrated that PP suppressed the proliferation, invasion, and drug-resistance of liver cancer cells in vitro and in vivo, mediated by the inhibition of autocrine VEGF-induced PI3K/AKT signaling pathway.
Journal ArticleDOI

Antioxidant and anti-aging activities of the polysaccharide TLH-3 from Tricholoma lobayense

TL;DR: It is suggested that polysaccharide TLH-3 possessed apparent antioxidant and anti-aging activities and could be exploited as a potent dietary supplement to attenuate aging and prevent age-related diseases in humans.
Related Papers (5)