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Medicinal mushroom: boon for therapeutic applications

TLDR
The present review focuses on the comprehensive account of the medicinal properties of various medicinal mushrooms, which will further help the researchers to understand the metabolites and find other metabolites from the mushrooms which can be used for the potential development of the drugs to treat various life-threatening diseases.
Abstract
Medicinal mushrooms are higher fungi with additional nutraceutical attributes having low fat content and a trans-isomer of unsaturated fatty acids along with high fibre content, triterpenes, phenolic compounds, sterols, eritadenine and chitosan. They are considered as the unmatched source of healthy foods and drugs. They have outstanding attractive taste, aroma and nutritional value, so are considered as functional food, which means they are beneficial to the body not only in terms of nutrition but also for improved health. Medicinal mushrooms and their extract have a large number of bioactive components called secondary metabolites. The presence of polysaccharide β-glucans or polysaccharide–protein complexes content in mushroom extract have great therapeutic applications in human health as they possess many properties such as anti-diabetic, anti-cancerous, anti-obesity, immunomodulatory, hypocholesteremia, hepatoprotective nature along with anti-aging. The present review focuses on the comprehensive account of the medicinal properties of various medicinal mushrooms. This will further help the researchers to understand the metabolites and find other metabolites as well from the mushrooms which can be used for the potential development of the drugs to treat various life-threatening diseases.

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Journal ArticleDOI

The biology of ergothioneine, an antioxidant nutraceutical.

TL;DR: Mushroom or ERG consumption seems to provide significant prevention against oxidative stress in a large variety of systems, and it may have value as a nutraceutical and antioxidant more generally.
Journal ArticleDOI

Current Prospects of Nutraceuticals: A Review.

TL;DR: An overview of various bioactive ingredients which act as nutraceuticals (carbohydrates, lipids, edible flowers, alkaloids, medicinal plants, etc.) and their role in health benefits has been discussed and further application of nutr pharmaceuticals in various diseases prevention has been also discussed.
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Molecular mechanistic insight of hepatitis B virus mediated hepatocellular carcinoma.

TL;DR: The molecular mechanisms that come from other than HBV endemic places which can be innovative approaches to treat HCC are outlined.
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Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products.

TL;DR: The current status of clinical studies on immunomodulatory activities of mushrooms and mushroom products are reviewed and the approaches that have been used in the development and application of bioactive compounds extracted from mushrooms are described.
Journal ArticleDOI

Edible Mushrooms as Functional Ingredients for Development of Healthier and More Sustainable Muscle Foods: A Flexitarian Approach.

TL;DR: In this article, the effects of functional ingredients of mushrooms in improving the quality and sensory attributes of nutritionally superior and next-generation healthier muscle food products are also highlighted in this paper.
References
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Journal ArticleDOI

Regulation of osteoclastogenesis by ganoderic acid DM isolated from Ganoderma lucidum.

TL;DR: The preventative effects of the ethanol extracts of Ganoderma lucidum against the ovariectomized (Ovx)-induced deterioration of bone density in 11-week-old female Sprague Dawley (SD) rats were investigated and the results showed that the G. lucidum-treated Ovx rats showed improved bone density compared with the Ovx Rats.
Journal ArticleDOI

Variation of the antimutagenicity effects of water extracts of Agaricus blazei Murrill in vitro.

TL;DR: This work evaluated the mutagenic and antimutagenic potential from aqueous extracts prepared in different temperatures from the lineage AB 97/29 in two basidiocarp phases (young and sporulated) and from A. blazei commercialized in Londrina-PR- Brazil, named here as AB PR, and in Piedade-SP-Brazil, named as AB SP.
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