Selenium for preventing cancer
Gabriele Dennert,Marcel Zwahlen,Maree Brinkman,Marco Vinceti,Maurice P. Zeegers,Markus Horneber +5 more
TLDR
Findings have limitations due to study design, quality and heterogeneity that complicate interpretation of the summary statistics, and some studies suggested that genetic factors may modify the relation between selenium and cancer risk-a hypothesis that deserves further investigation.Abstract:
Background
This review is an update of the first Cochrane publication on selenium for preventing cancer (Dennert 2011).
Selenium is a metalloid with both nutritional and toxicological properties. Higher selenium exposure and selenium supplements have been suggested to protect against several types of cancers.read more
Citations
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American Cancer Society guidelines on nutrition and physical activity for cancer prevention
Lawrence H. Kushi,Colleen Doyle,Marji McCullough,Cheryl L. Rock,Wendy Demark-Wahnefried,Elisa V. Bandera,Susan M. Gapstur,Alpa V. Patel,Kimberly S. Andrews,Ted Gansler +9 more
TL;DR: Recommendations for community action to accompany the 4 recommendations for individual choices to reduce cancer risk recognize that a supportive social and physical environment is indispensable if individuals at all levels of society are to have genuine opportunities to choose healthy behaviors.
Journal ArticleDOI
Selenium: an element for life
TL;DR: The evidence is at present conflicting as to whether Se supplementation is of benefit in patients with HT, though there are indications that it is advantageous in cases of mild/moderate Graves’ Orbitopathy and the role of Se in type 2 diabetes mellitus is ambiguous.
Journal ArticleDOI
A 10-Year Systematic Review of HIV/AIDS Mass Communication Campaigns: Have We Made Progress?
TL;DR: A 10-year systematic review of HIV/AIDS mass communication campaigns focused on sexual behavior, HIV testing, or both and to compare the results with the last comprehensive review of such campaigns, conducted by Myhre and Flora (2000), indicated that campaigns increasingly have employed the following strategies.
Journal ArticleDOI
Stigma, HIV and health : A qualitative synthesis
Lori A. Chambers,Sergio Rueda,Sergio Rueda,D. Nico Baker,Michael G. Wilson,Rachel Deutsch,Elmira Raeifar,Sean B. Rourke,Sean B. Rourke +8 more
TL;DR: Qualitative evidence indicates that HIV-related stigma within health contexts is a broad social phenomenon that manifests within multiple social spheres, including health care environments and that future stigma research should consider the social structures and societal practices that perpetuate and reinforce stigma and discrimination towards people with HIV.
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Oxidative stress mitigation by antioxidants - An overview on their chemistry and influences on health status.
Aurelia Magdalena Pisoschi,Aneta Pop,Florin Iordache,Loredana Stanca,Gabriel Predoi,Andreea Iren Serban +5 more
TL;DR: The present review paper focuses on the chemistry of oxidative stress mitigation by antioxidants, and the specific mechanism of a series of endogenous and exogenous antioxidants in particular aspects of oxidative Stress, is detailed.
References
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P T Higgins,Douglas G. Altman,Peter C Gøtzsche,Peter Jüni,David Moher,Andrew D Oxman,Jelena Savović,Kenneth F. Schulz,Laura Weeks,Jonathan A C Sterne +9 more
TL;DR: The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.
The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-Analyses
TL;DR: The Newcastle-Ottawa Scale (NOS) as discussed by the authors was developed to assess the quality of nonrandomised studies with its design, content and ease of use directed to the task of incorporating the quality assessments in the interpretation of meta-analytic results.
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