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Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy

TLDR
This review covers recent advances in the development of SPions together with their possibilities and limitations from fabrication to application in drug delivery and the state-of-the-art synthetic routes and surface modification of desired SPIONs for drug delivery purposes.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2011-01-01. It has received 1557 citations till now. The article focuses on the topics: Drug delivery.

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To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

TL;DR: Delivery of conventional chemotherapeutic anti-cancer drugs is mainly discussed and exploitation and the understanding of these characteristics to design new drug delivery systems targeting the tumor are focused on.
Journal ArticleDOI

Use of iron oxide nanomaterials in wastewater treatment: a review.

TL;DR: This review outlined the latest applications of iron oxide nanomaterials in wastewater treatment, and gaps which limited their large-scale field applications, as well as the outlook for potential applications and further challenges.
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy

TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
References
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Journal ArticleDOI

Toxic Potential of Materials at the Nanolevel

TL;DR: The establishment of principles and test procedures to ensure safe manufacture and use of nanomaterials in the marketplace is urgently required and achievable.
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Nano-sized transition-metal oxides as negative-electrode materials for lithium-ion batteries

TL;DR: It is reported that electrodes made of nanoparticles of transition-metal oxides (MO), where M is Co, Ni, Cu or Fe, demonstrate electrochemical capacities of 700 mA h g-1, with 100% capacity retention for up to 100 cycles and high recharging rates.
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Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications

TL;DR: This review discusses the synthetic chemistry, fluid stabilization and surface modification of superparamagnetic iron oxide nanoparticles, as well as their use for above biomedical applications.
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Understanding biophysicochemical interactions at the nano–bio interface

TL;DR: Probing the various interfaces of nanoparticle/biological interfaces allows the development of predictive relationships between structure and activity that are determined by nanomaterial properties such as size, shape, surface chemistry, roughness and surface coatings.
Journal ArticleDOI

Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications

TL;DR: Practical Interests of Magnetic NuclearRelaxation for the Characterization of Superparamagnetic Colloid, and Use of Nanoparticles as Contrast Agents forMRI20825.
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