Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.
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In 1992, Piette and colleagues suggested that the ACR revised criteria be reevaluated in light of the above discoveries, and the presence and clinical associations or antiphospholipid antibodies in patients with SLE was suggested.Abstract:
In 1982, the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology (ACR)published revised criteria for the classification of systemiclupus erythematosus (SLE) (1). During the ensuing decade several investigators, including Drs. Graham Hughes and Donato Alarcon-Segovia, among others, have described the presence and clinical associations or antiphospholipid antibodies in patients with SLE, as well as the occurrence of theprimary antiphospholipid syndrome (2-5). In 1992, Piette and colleagues suggested that the ACR revised criteria be reevaluated in light of the above discoveries (6).read more
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The impact of obesity in systemic lupus erythematosus on disease parameters, quality of life, functional capacity and the risk of atherosclerosis.
TL;DR: To study the effect of obesity on the quality of life, functional capacity and the risk of carotid atherosclerotic plaque formation in systemic lupus erythematosus patients and to correlate the findings with disease parameters, activity and damage.
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Effectively measuring adherence to medications for systemic lupus erythematosus in a clinical setting.
Sri Koneru,Michael Shishov,Avis E. Ware,Yolanda Farhey,Mongey Ab,T. Brent Graham,Murray H. Passo,J. Lawrence Houk,Gloria C. Higgins,Hermine I. Brunner +9 more
TL;DR: The MASRI appears to be a useful screening tool for nonadherence in patients with SLE that could be suitable for clinical practice and when combined with the MD scale, the measure has concurrent and predictive validity.
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Epigenetic Reprogramming in Naive CD4+ T Cells Favoring T Cell Activation and Non-Th1 Effector T Cell Immune Response as an Early Event in Lupus Flares
Patrick Coit,Mikhail G. Dozmorov,Joan T. Merrill,W. Joseph McCune,Kathleen Maksimowicz-McKinnon,Jonathan D. Wren,Amr H. Sawalha +6 more
TL;DR: Examination of DNA methylation in naive CD4+ T cells from lupus patients was undertaken to determine if epigenetic remodeling in CD4- T cells is an early event in l upus flares.
Journal ArticleDOI
Antinuclear antibody detection by automated multiplex immunoassay in untreated patients at the time of diagnosis.
Katrijn Op De Beeck,Pieter Vermeersch,Patrick Verschueren,Rene Westhovens,Godelieve Mariën,Daniel Engelbert Blockmans,Xavier Bossuyt,Xavier Bossuyt +7 more
TL;DR: Test result specific likelihood ratios and the presence of multiple autoantibodies help with the interpretation of data generated by multiplex immunoassays.
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Cutaneous Manifestations of Systemic Lupus Erythematosus
TL;DR: The SLE-specific cutaneous changes: malar rash, discoid rash, photosensitivity, and oral mucosal lesions as well as SLE nonspecific skin manifestations, their pathophysiology, and management are covered.
References
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Journal ArticleDOI
The 1982 revised criteria for the classification of systemic lupus erythematosus
Eng M. Tan,Alan S. Cohen,James F. Fries,Alfonse T. Masi,Dennis J. McShane,Naomi F. Rothfield,Jane G. Schaller,Norman Talal,Robert Winchester +8 more
TL;DR: The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification and showed gains in sensitivity and specificity.
Journal ArticleDOI
Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus
E. N. Harris,Boey Ml,C G Mackworth-Young,A. E. Gharavi,B. M. Patel,S. Loizou,Graham R. V. Hughes +6 more
TL;DR: A new solid-phase radioimmunoassay for the detection of anticardiolipin antibodies is 200-400 times more sensitive than the precipitation method used in the Venereal Disease Reference Laboratory test and appears to have predictive value for thrombosis in SLE and related disorders.
Journal ArticleDOI
Criteria for the diagnosis of lupus anticoagulants: an update. On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the ISTH.
Journal ArticleDOI
The "primary" antiphospholipid syndrome: major clinical and serological features.
Ronald A. Asherson,Munther A. Khamashta,José Ordi-Ros,Ronald H. W. M. Derksen,S J Machin,Jordi Barquinero,H H Outt,E. N. Harris,M Vilardell-Torres,Graham R. V. Hughes +9 more
TL;DR: The group of patients presented appears to be closely related, but distinctly separate from SLE, with a history of deep vein thromboses and a family history of SLE or a familial clotting tendency in a minority.
Journal Article
Evaluation of the anti-cardiolipin antibody test: report of an international workshop held 4 April 1986.
TL;DR: This study shows that properly performed ELISA or SRIA assays can be used to provide an accurate, reproducible, and quantitative measure of IgG and IgM aCL concentration in serum samples.
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