Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.
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TLDR
In 1992, Piette and colleagues suggested that the ACR revised criteria be reevaluated in light of the above discoveries, and the presence and clinical associations or antiphospholipid antibodies in patients with SLE was suggested.Abstract:
In 1982, the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology (ACR)published revised criteria for the classification of systemiclupus erythematosus (SLE) (1). During the ensuing decade several investigators, including Drs. Graham Hughes and Donato Alarcon-Segovia, among others, have described the presence and clinical associations or antiphospholipid antibodies in patients with SLE, as well as the occurrence of theprimary antiphospholipid syndrome (2-5). In 1992, Piette and colleagues suggested that the ACR revised criteria be reevaluated in light of the above discoveries (6).read more
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Randomized, Controlled Trial of Prednisone, Cyclophosphamide, and Cyclosporine in Lupus Membranous Nephropathy
TL;DR: Patients with lupus membranous nephropathy are at substantial long-term risk for morbidity and mortality associated with protracted nephrotic syndrome, including ESRD and regimens containing CsA or IVCY are each more effective than prednisone alone in inducing remission of proteinuria among patients with LMN.
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Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases
Shinji Fukaya,Shinsuke Yasuda,Toko Hashimoto,Kenji Oku,Hiroshi Kataoka,Tetsuya Horita,Tatsuya Atsumi,Takao Koike +7 more
TL;DR: The prevalence of HPS among in-hospital patients with systemic autoimmunity is not ignorable, and administration of immunosuppressants was effective in cases with autoimmune-associated HPS, whereas prognosis was poor in infection- associated HPS.
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Epidemiology of the rheumatic diseases in Mexico. A study of 5 regions based on the COPCORD methodology.
Ingris Peláez-Ballestas,Luz Helena Sanin,José Moreno-Montoya,José Alvarez-Nemegyei,Ruben Burgos-Vargas,Mario Alberto Garza-Elizondo,Jacqueline Rodriguez-Amado,M. V. Goycochea-Robles,Marco A. Madariaga,Jorge A. Zamudio,Natalia Santana,Mario H. Cardiel +11 more
TL;DR: Geographic variations in the prevalence of MSK pain and specific diagnoses suggested a role for geographic factors in thePrevalence of rheumatic diseases in 5 regions of México.
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Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus
Richard Furie,William Stohl,Ellen M. Ginzler,Michael Becker,Nilamadhab Mishra,W. Winn Chatham,Joan T. Merrill,Arthur Weinstein,W. Joseph McCune,John Zhong,Wendy Cai,William W. Freimuth +11 more
TL;DR: Belimumab was well tolerated and reduced peripheral B-cell levels in SLE patients and these data support further studies of belimumab in autoimmune disorders.
Journal ArticleDOI
Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus
Nan Shen,Qiong Fu,Qiong Fu,Yun Deng,Yun Deng,Xiaoxia Qian,Zhao Jian,Kenneth M. Kaufman,Yee Ling Wu,C. Yung Yu,Yuanjia Tang,Ji Yih Chen,Wanling Yang,Maida Wong,Aya Kawasaki,Naoyuki Tsuchiya,Takayuki Sumida,Yasushi Kawaguchi,Hwee Siew Howe,Mo Yin Mok,So Young Bang,Fei Lan Liu,Deh Ming Chang,Yoshinari Takasaki,Hiroshi Hashimoto,John B. Harley,Joel M. Guthridge,Jennifer M. Grossman,Rita M. Cantor,Yeong Wook Song,Sang Cheol Bae,Shunle Chen,Bevra H. Hahn,Yu-Lung Lau,Betty P. Tsao +34 more
TL;DR: A functional polymorphism in type I IFN pathway gene TLR7 predisposing to SLE is established, especially in Chinese and Japanese male subjects, with a stronger effect in male than female subjects.
References
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Journal ArticleDOI
The 1982 revised criteria for the classification of systemic lupus erythematosus
Eng M. Tan,Alan S. Cohen,James F. Fries,Alfonse T. Masi,Dennis J. McShane,Naomi F. Rothfield,Jane G. Schaller,Norman Talal,Robert Winchester +8 more
TL;DR: The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification and showed gains in sensitivity and specificity.
Journal ArticleDOI
Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus
E. N. Harris,Boey Ml,C G Mackworth-Young,A. E. Gharavi,B. M. Patel,S. Loizou,Graham R. V. Hughes +6 more
TL;DR: A new solid-phase radioimmunoassay for the detection of anticardiolipin antibodies is 200-400 times more sensitive than the precipitation method used in the Venereal Disease Reference Laboratory test and appears to have predictive value for thrombosis in SLE and related disorders.
Journal ArticleDOI
Criteria for the diagnosis of lupus anticoagulants: an update. On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the ISTH.
Journal ArticleDOI
The "primary" antiphospholipid syndrome: major clinical and serological features.
Ronald A. Asherson,Munther A. Khamashta,José Ordi-Ros,Ronald H. W. M. Derksen,S J Machin,Jordi Barquinero,H H Outt,E. N. Harris,M Vilardell-Torres,Graham R. V. Hughes +9 more
TL;DR: The group of patients presented appears to be closely related, but distinctly separate from SLE, with a history of deep vein thromboses and a family history of SLE or a familial clotting tendency in a minority.
Journal Article
Evaluation of the anti-cardiolipin antibody test: report of an international workshop held 4 April 1986.
TL;DR: This study shows that properly performed ELISA or SRIA assays can be used to provide an accurate, reproducible, and quantitative measure of IgG and IgM aCL concentration in serum samples.
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