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B. Brett Finlay
Researcher at University of British Columbia
Publications - 609
Citations - 69318
B. Brett Finlay is an academic researcher from University of British Columbia. The author has contributed to research in topics: Virulence & Effector. The author has an hindex of 135, co-authored 588 publications receiving 61894 citations. Previous affiliations of B. Brett Finlay include Vaccine and Infectious Disease Organization & Canadian Institute for Advanced Research.
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Journal ArticleDOI
The impact of the intestinal microbiome on human immune development and atopic disease
Leah T Thomas,Marie-Claire Arrieta,Pedro A. Dimitriu,Lisa Thorson,William W. Mohn,B. Brett Finlay,Stuart E. Turvey +6 more
TL;DR: This study will translate findings from murine studies supporting the hypothesis that the administration of probiotics or antibiotics during post-natal life alters the gut microbiome and ultimately the asthmatic symptoms of these mice into humans using stool samples obtained from the CHILD study.
Posted ContentDOI
MIND diet associated with later onset of Parkinson’s disease
A Metcalfe-Roach,AC Yu,E Golz,K Sundvick,Cirstea,D Kliger,LH Foulger,M Mackenzie,B. Brett Finlay,S Appel-Cresswell +9 more
TL;DR: Preliminary data suggest that the MIND diet may be an effective PD-delaying intervention, especially in women, and effect sizes exceeded those previously reported for the Mediterranean diet.
ComponentDOI
Crystal structure of enteropathogenic E.coli (EPEC) type III secretion system protein EscJ
C.K. Yip,T.G. Kimbrough,H.B. Felise,M. Vuckovic,N.A. Thomas,Richard A. Pfuetzner,Elizabeth A. Frey,B. Brett Finlay,S.I. Miller,Natalie C. J. Strynadka +9 more
Book ChapterDOI
Genome Plasticity in Salmonella enterica and Its Relevance to Host-Pathogen Interactions
TL;DR: Understanding the phenomenon of genome plasticity in this species is important to characterize the relationship between genetic variation and host adaptation, as well as the ability to cause a relatively minor gastrointestinal disease or a potentially life-threatening systemic fever.
Journal ArticleDOI
Salmonella and Enteropathogenic Escherichia coli Interactions with Host Cells: Signaling Pathways.
TL;DR: This review focuses on recent advances in understanding of the signaling events stemming from the host-pathogen interactions specific to Salmonella and EPEC.