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B. Brett Finlay
Researcher at University of British Columbia
Publications - 609
Citations - 69318
B. Brett Finlay is an academic researcher from University of British Columbia. The author has contributed to research in topics: Virulence & Effector. The author has an hindex of 135, co-authored 588 publications receiving 61894 citations. Previous affiliations of B. Brett Finlay include Vaccine and Infectious Disease Organization & Canadian Institute for Advanced Research.
Papers
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Journal ArticleDOI
Secretory IgA: Linking microbes, maternal health, and infant health through human milk.
TL;DR: In this paper , the authors highlight these new findings in the context of the critical early-life window and propose outstanding areas of study that will be key to harnessing the benefits of SIgA to support healthy immune development during infancy.
Journal ArticleDOI
Long-term survival of Salmonella enterica serovar Typhimurium reveals an infectious state that is underrepresented on laboratory media containing bile salts.
TL;DR: Cells in desiccated Salmonella enterica serovar Typhimurium rdar (red, dry, and rough) morphotype colonies were examined for culturability and infectivity after 30 months and were mildly attenuated compared to the infectivity of freshly grown cells.
Patent
Effectors of innate immunity determination
Robert E. W. Hancock,B. Brett Finlay,Monisha G. Scott,Dawn M. E. Bowdish,Carrie M. Rosenberger,Jon-Paul S. Powers +5 more
TL;DR: In this paper, a method of identifying a polynucleotide or pattern of polyn nucleotides regulated by one or more sepsis or inflammatory inducing agents and inhibited by a peptide is described.
Posted ContentDOI
Accurate identification and quantification of commensal microbiota bound by host immunoglobulins
Matthew A. Jackson,Claire Pearson,Nicholas E. Ilott,Kelsey E. Huus,Ahmed N. Hegazy,Ahmed N. Hegazy,Jonathan Webber,B. Brett Finlay,Andrew J. Macpherson,Fiona Powrie,Lilian H. Lam +10 more
TL;DR: A detailed IgA-Seq protocol to accurately isolate IgA -bound taxa from intestinal samples is provided and novel probability-based scores that adjust for the compositional nature of relative abundance data to accurately quantify taxon-level IgA binding are demonstrated.
Journal ArticleDOI
Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition.
Kelsey E. Huus,T. T. Hoang,A. Creus-Cuadros,Mihai Cirstea,S. L. Vogt,K. Knuff-Janzen,Philippe J. Sansonetti,Pascale Vonaesch,Pascale Vonaesch,B. Brett Finlay,B. Brett Finlay +10 more
TL;DR: In this paper, the authors show that Bacteroidaceae and Enterobacteriaceae are capable of multi-species symbiotic cross-feeding, resulting in synergistic growth of a mixed community in vitro.