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B. Brett Finlay
Researcher at University of British Columbia
Publications - 609
Citations - 69318
B. Brett Finlay is an academic researcher from University of British Columbia. The author has contributed to research in topics: Virulence & Effector. The author has an hindex of 135, co-authored 588 publications receiving 61894 citations. Previous affiliations of B. Brett Finlay include Vaccine and Infectious Disease Organization & Canadian Institute for Advanced Research.
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Src homology domain 2 adaptors affect adherence of Salmonella enterica serovar Typhimurium to non-phagocytic cells
TL;DR: The contribution of recruited Src homology 2 adaptor proteins to invasion was found that, while not involved in bacterial internalization itself, the adaptors Nck and ShcA influenced adherence of S. Typhimurium to non-phagocytic cells.
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Analysis of bacterial survival after exposure to reactive oxygen species or antibiotics.
Joris van der Heijden,Stefanie L. Vogt,Lisa A. Reynolds,Jorge Peña-Díaz,Audrey Tupin,Laurent Aussel,B. Brett Finlay +6 more
TL;DR: Supporting material is provided to further investigate the relationship between Salmonella typhimurium survival and oxidative stress and the percentage of surviving bacteria after exposure to hydrogen peroxide.
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A receptor for meningococcus: eliciting β-arrestin signaling for barrier breaching.
TL;DR: Type IV pili of Neisseria meningitidis-the causative bacterium of cerebrospinal meningitis-bind to the endothelial β2-adrenoceptor and elicit biased β-arrestin signaling resulting in microvilli formation and paracytotic bacterial migration.
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Modeling enteropathogenic and enterohemorrhagic E. coli infections and disease
TL;DR: Important agents of infectious diarrhea, these microbes cause the death of several hundred thousand children worldwide each year and recent advances in modeling these pathogens, as well as sequencing of the EHEC O157 genome have revolutionized understanding of how these microbes infect their hosts and cause disease.