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Bruce R. Lawford

Researcher at Queensland University of Technology

Publications -  100
Citations -  4341

Bruce R. Lawford is an academic researcher from Queensland University of Technology. The author has contributed to research in topics: Alcohol dependence & Schizophrenia. The author has an hindex of 33, co-authored 98 publications receiving 3735 citations. Previous affiliations of Bruce R. Lawford include University of Queensland & Greenslopes Private Hospital.

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International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Caroline M. Nievergelt, +213 more
TL;DR: A GWAS from the Psychiatric Genomics Consortium is reported in which two risk loci in European ancestry and one locus in African ancestry individuals are identified and it is found that PTSD is genetically correlated with several other psychiatric traits.
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Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients

TL;DR: In this article, a post-mortem human brain tissue from 24 patients with schizophrenia and 24 unaffected controls was analyzed and DNA methylation was assessed at over 485,000 CpG sites using the Illumina Infinium HumanMethylation450 Bead Chip.
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Bromocriptine in the treatment of alcoholics with the D2 dopamine receptor A1 allele.

TL;DR: In a double-blind study, bromocriptine, a DRD2 agonist, or placebo was administered to alcoholics with either the A1 or A2 genotypes or only the A2 (A2/A2 genotype) allele of theDRD2 gene, and the greatest improvement in craving and anxiety occurred in the bromOCriptine-treated A1 alcoholics.
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The D2 dopamine receptor A1 allele and opioid dependence: Association with heroin use and response to methadone treatment

TL;DR: The results indicate that DRD2 variants are predictors of heroin use and subsequent methadone treatment outcome and suggest a pharmacogenetic approach to the treatment of opioid dependence.