scispace - formally typeset
D

David E. Riley

Researcher at Case Western Reserve University

Publications -  73
Citations -  5885

David E. Riley is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Tourette syndrome & Parkinson's disease. The author has an hindex of 31, co-authored 73 publications receiving 5266 citations. Previous affiliations of David E. Riley include University Hospitals of Cleveland & Veterans Health Administration.

Papers
More filters
Journal ArticleDOI

Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.

TL;DR: Initial treatment with pramipexole resulted in lower incidences of freezing, somnolence, and edema and provided for better symptomatic control, as measured by the Unified Parkinson's Disease Rating Scale, compared with initial treatment with levodopa, which resulted in similar quality of life.
Journal ArticleDOI

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

Günter U. Höglinger, +140 more
- 01 Jul 2011 - 
TL;DR: Two independent variants in MAPT affecting risk for PSP are confirmed, one of which influences MAPT brain expression and the genes implicated encode proteins for vesicle-membrane fusion at the Golgi-endosomal interface and for a myelin structural component.
Journal ArticleDOI

Cortical-basal ganglionic degeneration

TL;DR: This condition is more frequent than previously believed, and the diagnosis can be predicted during life on the basis of clinical findings, however, as with other "degenerative" diseases of the nervous system, a definitive diagnosis requires confirmation by autopsy.
Journal ArticleDOI

Prospective randomized double-blind trial of bilateral thalamic deep brain stimulation in adults with Tourette syndrome.

TL;DR: Bilateral thalamic DBS appears to reduce tic frequency and severity in some patients with TS who have exhausted other available means of treatment and are likely to be medically refractory.