Enrique Carrillo-de-Santa-Pau

TL;DR: A genome-wide association analysis in the UK Biobank and INTERVAL studies is performed, providing evidence of shared genetic pathways linking blood cell indices with complex pathologies, including autoimmune diseases, schizophrenia, and coronary heart disease and evidence suggesting previously reported population associations betweenBlood cell indices and cardiovascular disease may be non-causal.

TL;DR: It is indicated that STAG2 is a new UBC tumor suppressor acting through mechanisms that are different from its role in preventing aneuploidy, and its loss was associated with improved outcome.

TL;DR: The results demonstrate a tight connection between somatic mutation, DNA methylation and transcriptional control in key B cell pathways deregulated differentially in Burkitt lymphoma and other germinal center B cell lymphomas.

TL;DR: An epithelial-cell-autonomous basal pre-inflammatory state in the pancreas of Nr5a2+/− mice is described that is reminiscent of the early stages of pancreatitis-induced inflammation and is conserved in histologically normal human pancreases with reduced expression of NR5A2 mRNA.

TL;DR: A cell line classification that establishes their relatedness to the major molecularly-defined bladder tumor subtypes is provided and should help to select cell lines appropriate for the functional analysis of bladder cancer genes, for example those being identified through massive parallel sequencing.