Estefanía Rodríguez

TL;DR: The findings of a World Health Organization expert working group that is developing animal models to test vaccines and therapeutic agents for the treatment of COVID-19, and their relevance for preclinical testing, are reviewed.

TL;DR: Both MAPK pathways are essential for cell survival under these circumstances because mutant strains deficient in different components of both pathways are hypersensitive to zymolyase.

TL;DR: Using the biostatistical model, it is predicted that 50% and 90% of male survivors clear Ebola virus RNA from seminal fluid at 115 days (90% prediction interval 72-160) and 294 days (212-399) after disease onset, respectively, and the number of men positive for Ebola virusRNA in affected countries would decrease from about 50 in January 2016, to fewer than 1 person by July, 2016.

TL;DR: It is shown that increased expression of KLF6-SV1 is associated with decreased survival in patients with lung adenocarcinoma, and targeted reduction of KLFsV1 using siRNA induces apoptosis both alone and in combination with the chemotherapeutic drug cisplatin.

TL;DR: An international community‐driven resource called “Minimal Information for Standardization of Humanized Mice” (MISHUM) has been created for the purpose of enhancing rigor and reproducibility of studies in the field.