K
Koert J. Stittelaar
Researcher at Erasmus University Rotterdam
Publications - 78
Citations - 3469
Koert J. Stittelaar is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Virus & Vaccination. The author has an hindex of 29, co-authored 74 publications receiving 2783 citations. Previous affiliations of Koert J. Stittelaar include Centre for Health Protection.
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Journal ArticleDOI
Animal models for COVID-19.
César Muñoz-Fontela,William E. Dowling,Simon G. P. Funnell,Pierre Stéphane Gsell,A. Ximena Riveros-Balta,Randy A. Albrecht,Hanne Leth Andersen,Ralph S. Baric,Miles W. Carroll,Marco Cavaleri,Chuan Qin,Ian Crozier,Kai Dallmeier,Leon de Waal,Emmie de Wit,Leen Delang,Erik D. Dohm,W. Paul Duprex,Darryl Falzarano,Courtney L. Finch,Matthew B. Frieman,Barney S. Graham,Lisa E. Gralinski,Kate Guilfoyle,Bart L. Haagmans,Geraldine A. Hamilton,Amy L. Hartman,Sander Herfst,Suzanne J.F. Kaptein,William B. Klimstra,Ivana Knezevic,Philip R. Krause,Jens H. Kuhn,Roger Le Grand,Mark G. Lewis,Wen-Chun Liu,Pauline Maisonnasse,Anita K. McElroy,Vincent J. Munster,Nadia Oreshkova,Angela L. Rasmussen,Joana Rocha-Pereira,Barry Rockx,Estefanía Rodríguez,Thomas F. Rogers,Francisco J. Salguero,Michael Schotsaert,Koert J. Stittelaar,Hendrik Jan Thibaut,Chien Te K. Tseng,Júlia Vergara-Alert,Martin Beer,Trevor Brasel,Jasper Fuk-Woo Chan,Adolfo García-Sastre,Johan Neyts,Stanley Perlman,Douglas S. Reed,Juergen A. Richt,Chad J. Roy,Joaquim Segalés,Seshadri S. Vasan,Seshadri S. Vasan,Ana Maria Henao-Restrepo,Dan H. Barouch +64 more
TL;DR: The findings of a World Health Organization expert working group that is developing animal models to test vaccines and therapeutic agents for the treatment of COVID-19, and their relevance for preclinical testing, are reviewed.
Journal ArticleDOI
Modified Vaccinia Virus Ankara Protects Macaques against Respiratory Challenge with Monkeypox Virus
Koert J. Stittelaar,Geert van Amerongen,Ivanela Kondova,Thijs Kuiken,Rob van Lavieren,Frank H. M. Pistoor,Hubert G. M. Niesters,Gerard J. J. van Doornum,Ben A. M. van der Zeijst,Luis Mateo,Paul Chaplin,Albert D. M. E. Osterhaus +11 more
TL;DR: The MVA-based smallpox vaccine protected macaques against a lethal respiratory challenge with monkeypox virus and is therefore an important candidate for the protection of humans against smallpox.
Journal ArticleDOI
Safety of modified vaccinia virus Ankara (MVA) in immune-suppressed macaques
Koert J. Stittelaar,Thijs Kuiken,Rik L. de Swart,Geert van Amerongen,Helma W. Vos,Hubert G. M. Niesters,Pim van Schalkwijk,Theo H. van der Kwast,Linda S. Wyatt,Bernard Moss,Albert D. M. E. Osterhaus +10 more
TL;DR: The data suggest that MVA can safely be used as a basis for recombinant human vaccines, and that it is also safe for use in immunocompromised individuals.
Journal ArticleDOI
Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection
Koert J. Stittelaar,Johan Neyts,Lieve Naesens,Geert van Amerongen,Rob van Lavieren,Antonín Holý,Erik De Clercq,Hubert G. M. Niesters,Edwin Fries,Chantal Maas,Paul G.H. Mulder,Ben A. M. van der Zeijst,Albert D. M. E. Osterhaus +12 more
TL;DR: Comparing the effectiveness of post-exposure smallpox vaccination and antiviral treatment after lethal intratracheal infection of cynomolgus monkeys with monkeypox virus shows that adequate preparedness for a biological threat involving smallpox should include the possibility of treating exposed individuals with antiviral compounds such as cidofovir or other selective anti-poxvirus drugs.
Journal ArticleDOI
Cross-protection against lethal H5N1 challenge in ferrets with an adjuvanted pandemic influenza vaccine.
Benoît Baras,Koert J. Stittelaar,James H. Simon,Robert J. M. M. Thoolen,Sally Mossman,Frank H. M. Pistoor,Geert van Amerongen,Martine Wettendorff,Emmanuel Hanon,Albert D. M. E. Osterhaus +9 more
TL;DR: Protection data in a stringent challenge model in association with an excellent clinical profile highlight the potential of this adjuvanted H5N1 candidate vaccine as an effective tool in pandemic preparedness.