G
Gad Getz
Researcher at Broad Institute
Publications - 627
Citations - 309042
Gad Getz is an academic researcher from Broad Institute. The author has contributed to research in topics: Cancer & Biology. The author has an hindex of 189, co-authored 520 publications receiving 247560 citations. Previous affiliations of Gad Getz include University of Colorado Denver & University of California, San Diego.
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Journal ArticleDOI
Integrative pathway enrichment analysis of multivariate omics data
Marta Paczkowska,Jonathan Barenboim,N Sintupisut,Natalie S. Fox,Helen He Zhu,Diala Abd-Rabbo,Miles W Mee,Paul C. Boutros,Federico Abascal,Samirkumar B. Amin,Gary D. Bader,Rameen Beroukhim,Johanna Bertl,Keith A. Boroevich,Søren Brunak,Peter J. Campbell,Joana Carlevaro-Fita,Dimple Chakravarty,Calvin Wing Yiu Chan,Ken Chen,Jung Kyoon Choi,Jordi Deu-Pons,Priyanka Dhingra,Klev Diamanti,Lars Feuerbach,J Fink,Nuno A. Fonseca,Joan Frigola,C Gambacorti Passerini,Dale W. Garsed,Mark Gerstein,Gad Getz,Abel Gonzalez-Perez,Qianyun Guo,Ivo Gut,David Haan,Mark P. Hamilton,Nicholas J. Haradhvala,Arif Harmanci,Mohamed Helmy,Carl Herrmann,Julian M. Hess,Asger Hobolth,Ermin Hodzic,Chen Hong,Henrik Hornshøj,Keren Isaev,Jose M. G. Izarzugaza,Rory Johnson,Toby Johnson,Malene Juul,Randi Istrup Juul,André Kahles,Abdullah Kahraman,Manolis Kellis,Ekta Khurana,Jong Kyoung Kim,Young-Wook Kim,Jan Komorowski,Jan O. Korbel,Swathi Ashok Kumar,Andrés Lanzós,Mitchell G. Lawrence,Darlene Lee,Kjong-Van Lehmann,Shantao Li,Xiaotong Li,Z Lin,Eric Minwei Liu,Lucas Lochovsky,Shaoke Lou,Tobias Madsen,Kathleen Marchal,Inigo Martincorena,Alexander Martinez-Fundichely,Yosef E. Maruvka,Patrick McGillivray,William Meyerson,Ferran Muiños,Loris Mularoni,Hidewaki Nakagawa,Morten Nielsen,Kiejung Park,Jakob Skou Pedersen,Oriol Pich,Tirso Pons,Sergio Pulido-Tamayo,Benjamin J. Raphael,I Reyes-Salazar,Matthew A. Reyna,Ester Rheinbay,Mark A. Rubin,Carlota Rubio-Perez,Radhakrishnan Sabarinathan,Suleyman Cenk Sahinalp,Gordon Saksena,Leonidas Salichos,Cindy Sander,Steve Schumacher,Mark Shackleton,Ofer Shapira,Ciyue Shen,Raunak Shrestha,Shimin Shuai,Nikos Sidiropoulos,Lina Sieverling,Nicholas A Sinnott-Armstrong,Lincoln Stein,Joshua M. Stuart,David Tamborero,Grace Tiao,Tatsuhiko Tsunoda,Husen M. Umer,Liis Uusküla-Reimand,Alfonso Valencia,Miguel Vazquez,Lieven Verbeke,Claes Wadelius,Lina Wadi,Jian Wang,Jonathan Warrell,Sebastian M. Waszak,Joachim Weischenfeldt,D Wheeler,Guanming Wu,Jun Yu,Jiashan Zhang,Xiuqing Zhang,Yan Zhang,Zhongming Zhao,Lihua Zou,C. Von Mering,Jüri Reimand +132 more
TL;DR: The authors develop ActivePathways method, which uses data fusion techniques for integrative pathway analysis of multi-omics data and candidate gene discovery that discovers significantly enriched pathways across multiple datasets using statistical data fusion.
Journal ArticleDOI
Data analysis: Create a cloud commons
TL;DR: Major funding agencies should ensure that large biological data sets are stored in cloud services to enable easy access and fast analysis, say Lincoln D. Stein and colleagues.
Journal ArticleDOI
Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer
David Liu,David Liu,Philip Abbosh,Daniel Keliher,Daniel Keliher,Brendan Reardon,Brendan Reardon,Diana Miao,Diana Miao,Kent W. Mouw,Amaro Weiner-Taylor,Stephanie A. Wankowicz,Stephanie A. Wankowicz,Garam Han,Garam Han,Min Yuen Teo,Catharine Kline Cipolla,Jaegil Kim,Gopa Iyer,Hikmat Al-Ahmadie,Essel Dulaimi,David Y.T. Chen,R. Katherine Alpaugh,Jean H. Hoffman-Censits,Levi A. Garraway,Levi A. Garraway,Gad Getz,Scott L. Carter,Scott L. Carter,Joaquim Bellmunt,Joaquim Bellmunt,Elizabeth R. Plimack,Jonathan E. Rosenberg,Eliezer M. Van Allen,Eliezer M. Van Allen +34 more
TL;DR: It is found that post- treatment tumor heterogeneity predicts worse overall survival, and alterations in cell-cycle and immune checkpoint regulation genes in post-treatment tumors are observed, highlighting the impact of intratumor heterogeneity on survival.
Journal ArticleDOI
CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours
Rebecca C. Larson,Michael Kann,Stefanie R. Bailey,Nicholas J. Haradhvala,Paula Montero Llopis,Amanda A. Bouffard,Irene Scarfò,Mark B. Leick,Korneel Grauwet,Trisha R. Berger,Kai Stewart,Praju Anekal,Max Jan,J. Keith Joung,Andrea Schmidts,Tamara Ouspenskaia,Travis Law,Aviv Regev,Gad Getz,Marcela V. Maus +19 more
TL;DR: It is found that liquid and solid tumours differ in their interactions with CAR T cells and this work suggests that enhancing binding interactions between T cell and tumour cells may yield improved responses inSolid tumours.
Journal ArticleDOI
Erratum: The somatic genomic landscape of glioblastoma (Cell (2013) 155 (462-477))
Cameron Brennan,Roel G.W. Verhaak,Aaron McKenna,Benito Campos,Houtan Noushmehr,Sofie R. Salama,Siyuan Zheng,Debyani Chakravarty,J. Zachary Sanborn,Samuel H. Berman,Rameen Beroukhim,Brady Bernard,Chang-Jiun Wu,Giannicola Genovese,Ilya Shmulevich,Jill S. Barnholtz-Sloan,Lihua Zou,Rahulsimham Vegesna,Sachet A. Shukla,Giovanni Ciriello,W. K. Yung,Wei Zhang,Carrie Sougnez,Tom Mikkelsen,Kenneth Aldape,Darell D. Bigner,Erwin G. Van Meir,Michael D. Prados,Andrew E. Sloan,Keith L. Black,Jennifer M. Eschbacher,Gaetano Finocchiaro,William A. Friedman,David W. Andrews,Abhijit Guha,Mary Iacocca,Brian P. O'Neill,Greg Foltz,Jerome Myers,Daniel J. Weisenberger,Robert Penny,Raju Kucherlapati,Charles M. Perou,D. Neil Hayes,Richard A. Gibbs,Marco A. Marra,Gordon B. Mills,Eric S. Lander,Paul T. Spellman,Rick K. Wilson,Chris Sander,John N. Weinstein,Matthew Meyerson,Stacey Gabriel,Peter W. Laird,David Haussler,Gad Getz,Lynda Chin +57 more