G
Gaylor Boulay
Researcher at Harvard University
Publications - 34
Citations - 1567
Gaylor Boulay is an academic researcher from Harvard University. The author has contributed to research in topics: Chromatin & Tumor suppressor gene. The author has an hindex of 17, co-authored 30 publications receiving 1169 citations. Previous affiliations of Gaylor Boulay include Lille University of Science and Technology & Pasteur Institute.
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Journal ArticleDOI
Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain.
Gaylor Boulay,Gabriel J. Sandoval,Nicolo Riggi,Sowmya Iyer,Rémi Buisson,Beverly Naigles,Mary E. Awad,Shruthi Rengarajan,Angela Volorio,Matthew J. McBride,Matthew J. McBride,Liliane C. Broye,Lee Zou,Ivan Stamenkovic,Cigall Kadoch,Cigall Kadoch,Miguel Rivera,Miguel Rivera +17 more
TL;DR: It is demonstrated that the physical properties of prion-like domains can retarget critical chromatin regulatory complexes to establish and maintain oncogenic gene expression programs in cancer.
Journal ArticleDOI
EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma
Nicolo Riggi,Nicolo Riggi,Birgit Knoechel,Shawn M. Gillespie,Shawn M. Gillespie,Shawn M. Gillespie,Esther Rheinbay,Esther Rheinbay,Gaylor Boulay,Gaylor Boulay,Mario L. Suvà,Mario L. Suvà,Nikki E. Rossetti,Wannaporn E. Boonseng,Ozgur Oksuz,Edward B. Cook,Aurélie Formey,Anoop P. Patel,Anoop P. Patel,Melissa Gymrek,Melissa Gymrek,Vishal Thapar,Vikram Deshpande,David T. Ting,Francis J. Hornicek,G. Petur Nielsen,Ivan Stamenkovic,Martin J. Aryee,Martin J. Aryee,Bradley E. Bernstein,Bradley E. Bernstein,Bradley E. Bernstein,Miguel Rivera,Miguel Rivera +33 more
TL;DR: Divergent chromatin-remodeling patterns repress tumor suppressors and mesenchymal lineage regulators while activating oncogenes and potential therapeutic targets, such as the kinase VRK1.
Journal ArticleDOI
The Transcription Factor Encyclopedia
Dimas Yusuf,Stefanie L. Butland,Magdalena I. Swanson,Eugene Bolotin,Amy Ticoll,Warren A. Cheung,Xiao Yu Cindy Zhang,Christopher Td Dickman,Debra L. Fulton,Jonathan Lim,Jake Schnabl,Oscar H. P. Ramos,Mireille Vasseur-Cognet,Charles N. de Leeuw,Elizabeth M. Simpson,Gerhart U. Ryffel,Eric Lam,Ralf Kist,Miranda Sc Wilson,Raquel Marco-Ferreres,Jan J. Brosens,Leonardo Beccari,Paola Bovolenta,Bérénice A. Benayoun,Lara J. Monteiro,Helma Dc Schwenen,Lars Grøntved,Elizabeth D. Wederell,Susanne Mandrup,Reiner A. Veitia,Harini Chakravarthy,Pamela A. Hoodless,M. Michela Mancarelli,Bruce E. Torbett,Alison H. Banham,Sekhar P. Reddy,Rebecca L. Cullum,Michaela Liedtke,Mario P. Tschan,Michelle Vaz,Angie Rizzino,Mariastella Zannini,Seth Frietze,Peggy J. Farnham,Astrid Eijkelenboom,Philip J. Brown,David Laperrière,Dominique Leprince,Tiziana de Cristofaro,Kelly L. Prince,Marrit Putker,Luis del Peso,Gieri Camenisch,Roland H. Wenger,Michal Mikula,Marieke Rozendaal,Sylvie Mader,Jerzy Ostrowski,Simon J. Rhodes,Capucine Van Rechem,Gaylor Boulay,Sam W. Z. Olechnowicz,Mary B. Breslin,Michael S. Lan,Kyster K. Nanan,Michael Wegner,Juan Hou,Rachel D. Mullen,Stephanie C. Colvin,Peter J. Noy,Carol F. Webb,Matthew E. Witek,Scott Ferrell,Juliet M. Daniel,Jason Y. Park,Scott A. Waldman,Daniel J. Peet,Michael J. Taggart,Padma-Sheela Jayaraman,Julien J. Karrich,Bianca Blom,Farhad Vesuna,Henriette O'Geen,Yunfu Sun,Richard M. Gronostajski,Mark W. Woodcroft,Margaret R. Hough,Edwin Chen,Nicholas Europe-Finner,Magdalena Karolczak-Bayatti,Jarrod Bailey,Oliver Hankinson,Venu Raman,David P. LeBrun,Shyam Biswal,Christopher J. Harvey,Jason P. DeBruyne,John B. Hogenesch,Robert F. Hevner,Christophe Héligon,Xin M. Luo,Marissa Cathleen Blank,Kathleen J. Millen,David S. Sharlin,Douglas Forrest,Karin Dahlman-Wright,Chunyan Zhao,Yuriko Mishima,Satrajit Sinha,Rumela Chakrabarti,Elodie Portales-Casamar,Frances M. Sladek,Philip Bradley,Wyeth W. Wasserman +113 more
TL;DR: The Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and collaboration, is presented.
Journal ArticleDOI
Differential Regulation of HIC1 Target Genes by CtBP and NuRD, via an Acetylation/SUMOylation Switch, in Quiescent versus Proliferating Cells
Capucine Van Rechem,Gaylor Boulay,Sébastien Pinte,Nicolas Stankovic-Valentin,Cateline Guérardel,Dominique Leprince +5 more
TL;DR: It is demonstrated that HIC1/MTA1 complexes bind on two new target genes, Cyclin D1 and p57KIP2 in quiescent but not in growing WI38 cells, suggesting growth control.
Journal ArticleDOI
HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors.
Capucine Fleuriel,Majid Touka,Gaylor Boulay,Cateline Guérardel,Brian R. Rood,Dominique Leprince +5 more
TL;DR: This review will discuss how this epigenetic inactivation of HIC1 might "addict" cancer cells to altered survival and signaling pathways or to lineage-specific transcription factors during the early stages of tumorigenesis.