G
Giovanni B. Frisoni
Researcher at University of Geneva
Publications - 956
Citations - 55940
Giovanni B. Frisoni is an academic researcher from University of Geneva. The author has contributed to research in topics: Dementia & Medicine. The author has an hindex of 101, co-authored 871 publications receiving 46199 citations. Previous affiliations of Giovanni B. Frisoni include Geneva College & University of Rome Tor Vergata.
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Association of chronic non-steroidal anti-inflammatory drugs use and cognitive decline in non-demented elderly patients admitted to a geriatric evaluation and rehabilitation unit.
TL;DR: A positive association between chronic NSAID use and cognitive function in non-demented elderly patients is supported and Randomized controlled trials will be needed to definitively prove this beneficial effect.
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The strategic biomarker roadmap for the validation of Alzheimer’s diagnostic biomarkers: methodological update
Marina Boccardi,Marina Boccardi,Alessandra Dodich,Alessandra Dodich,Emiliano Albanese,Angèle Gayet-Ageron,Cristina Festari,Nicholas J. Ashton,Gérard N. Bischof,Konstantinos Chiotis,Konstantinos Chiotis,Antoine Leuzy,Emma E. Wolters,Martin A. Walter,Gil D. Rabinovici,Maria C. Carrillo,Alexander Drzezga,Alexander Drzezga,Alexander Drzezga,Oskar Hansson,Agneta Nordberg,Agneta Nordberg,Rik Ossenkoppele,Rik Ossenkoppele,Victor L. Villemagne,Bengt Winblad,Bengt Winblad,Giovanni B. Frisoni,Valentina Garibotto +28 more
TL;DR: The 2017 Alzheimer's disease (AD) Strategic Biomarker Roadmap (SBR) as discussed by the authors structured the validation of AD diagnostic biomarkers into five phases, systematically assessing analytical validity (Phases 1-2), clinical validity (phases 3-4), and clinical utility (phase 5) through primary and secondary Aims.
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The CST3 B haplotype is associated with frontotemporal lobar degeneration
Luisa Benussi,Roberta Ghidoni,Daniela Galimberti,Marina Boccardi,Chiara Fenoglio,Elio Scarpini,Giovanni B. Frisoni,G. Binetti +7 more
TL;DR: This study determined whether the cystatin C gene (CST3) was genetically associated with FTLD, a common cause of early‐onset dementia.
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Psychic correlates of sleep symptoms in the elderly
Giovanni B. Frisoni,Diego De Leo,Renzo Rozzini,Maria Bernardini,Marirosa Dello Buono,Marco Trabucchi +5 more
TL;DR: Night sleep symptoms and their relationship to a number of psychic, somatic and social variables were investigated and waking up frequently in the night showed a correlation pattern with psychic, social and somatic variables different from the other sleep symptoms, suggesting a different cause.
Journal ArticleDOI
Analysis of brain atrophy and local gene expression in genetic frontotemporal dementia
Andre Altmann,David M. Cash,David M. Cash,Martina Bocchetta,Carolin Heller,Regina H. Reynolds,Katrina M. Moore,Rhian S Convery,David L. Thomas,John C. van Swieten,Fermin Moreno,Raquel Sánchez-Valle,Barbara Borroni,Robert Laforce,Mario Masellis,Maria Carmela Tartaglia,Caroline Graff,Caroline Graff,Daniela Galimberti,James B. Rowe,Elizabeth Finger,Matthis Synofzik,Matthis Synofzik,Rik Vandenberghe,Alexandre de Mendonça,Fabrizio Tagliavini,Isabel Santana,Simon Ducharme,Simon Ducharme,Christopher C Butler,Alexander Gerhard,Alexander Gerhard,Johannes Levin,Johannes Levin,Adrian Danek,Giovanni B. Frisoni,Roberta Ghidoni,Sandro Sorbi,Markus Otto,Mina Ryten,Jonathan D. Rohrer,Genfi Genetic Ftd Initiative +41 more
TL;DR: The analysis suggests that these cell types may play a more active role in the onset of neurodegeneration in frontotemporal dementia than previously assumed, and in the case of the positively associated cell marker genes, potentially through emergence of neurotoxic astrocytes and alteration in the blood–brain barrier, respectively.