G
Giovanni B. Frisoni
Researcher at University of Geneva
Publications - 956
Citations - 55940
Giovanni B. Frisoni is an academic researcher from University of Geneva. The author has contributed to research in topics: Dementia & Medicine. The author has an hindex of 101, co-authored 871 publications receiving 46199 citations. Previous affiliations of Giovanni B. Frisoni include Geneva College & University of Rome Tor Vergata.
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Journal ArticleDOI
Coalition Against Major Diseases/European Medicines Agency biomarker qualification of hippocampal volume for enrichment of clinical trials in predementia stages of Alzheimer's disease
Derek L. G. Hill,Adam J. Schwarz,Maria Isaac,Luca Pani,Spiros Vamvakas,Robert Hemmings,Maria C. Carrillo,Peng Yu,Jia Sun,Jia Sun,Laurel A. Beckett,Marina Boccardi,James B. Brewer,Martha Brumfield,Marc Cantillon,Patricia E. Cole,Nick C. Fox,Giovanni B. Frisoni,Clifford R. Jack,Thomas Kelleher,Feng Luo,Gerald Novak,Paul Maguire,Richard Meibach,Patricia Patterson,Lisa J. Bain,Cristina Sampaio,David Raunig,Holly Soares,Joyce Suhy,Huanli Wang,Robin Wolz,Diane Stephenson +32 more
TL;DR: Regulatory qualification of a biomarker for a defined context of use provides scientifically robust assurances to sponsors and regulators that accelerate appropriate adoption of biomarkers into drug development.
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Prediction of AD dementia by biomarkers following the NIA-AA and IWG diagnostic criteria in MCI patients from three European memory clinics
Annapaola Prestia,Anna Caroli,Sara Wade,Sara Wade,Wiesjie M. van der Flier,Rik Ossenkoppele,Bart N.M. van Berckel,Frederik Barkhof,Charlotte E. Teunissen,Anders Wall,Stephen F. Carter,Michael Schöll,Il Han Choo,Il Han Choo,Agneta Nordberg,Agneta Nordberg,Philip Scheltens,Giovanni B. Frisoni +17 more
TL;DR: This work aims to compare the accuracy of these biomarkers, individually and in combination, in predicting AD among mild cognitive impairment (MCI) patients.
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Abnormal hippocampal shape in offenders with psychopathy.
Marina Boccardi,Rossana Ganzola,Roberta Rossi,Francesca Sabattoli,Mikko P. Laakso,Eila Repo-Tiihonen,Olli Vaurio,Mervi Könönen,Hannu J. Aronen,Paul M. Thompson,Giovanni B. Frisoni,Jari Tiihonen +11 more
TL;DR: The results indicate that habitually violent offenders exhibit a specific abnormal hippocampal morphology, in the absence of total gray matter volume changes, that may relate to different autonomic modulation and abnormal fear‐conditioning.
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Microstructural Diffusion Changes are Independent of Macrostructural Volume Loss in Moderate to Severe Alzheimer's Disease
Elisa Canu,Donald G. McLaren,Michele E. Fitzgerald,Barbara B. Bendlin,Giada Zoccatelli,Franco Alessandrini,Francesca B. Pizzini,Giuseppe Ricciardi,Alberto Beltramello,Sterling C. Johnson,Giovanni B. Frisoni +10 more
TL;DR: Stochastic measures of microstructure provide unique information not obtainable with volumetric mapping in regions known to be pivotal in AD and in those thought to be spared, and provides great understanding of the topography of pathological changes in AD that can be captured with imaging.
Journal ArticleDOI
Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum.
Isabelle Bos,Stephanie J.B. Vos,Frans R.J. Verhey,Philip Scheltens,Charlotte E. Teunissen,Sebastiaan Engelborghs,Kristel Sleegers,Giovanni B. Frisoni,Olivier Blin,Jill C. Richardson,Régis Bordet,Magda Tsolaki,Julius Popp,Julius Popp,Gwendoline Peyratout,Pablo Martinez-Lage,Mikel Tainta,Alberto Lleó,Peter Johannsen,Yvonne Freund-Levi,Yvonne Freund-Levi,Lutz Frölich,Rik Vandenberghe,Sarah Westwood,Valerija Dobricic,Frederik Barkhof,Frederik Barkhof,Cristina Legido-Quigley,Cristina Legido-Quigley,Lars Bertram,Lars Bertram,Lars Bertram,Simon Lovestone,Johannes Streffer,Ulf Andreasson,Ulf Andreasson,Kaj Blennow,Kaj Blennow,Henrik Zetterberg,Pieter Jelle Visser,Pieter Jelle Visser +40 more
TL;DR: This work investigated relations between amyloid‐β status, apolipoprotein E (APOE) ε4, and cognition, with cerebrospinal fluid markers of neurogranin (Ng), neurofilament light (NFL), YKL‐40, and total tau (T‐tau).