G
Giovanni B. Frisoni
Researcher at University of Geneva
Publications - 956
Citations - 55940
Giovanni B. Frisoni is an academic researcher from University of Geneva. The author has contributed to research in topics: Dementia & Medicine. The author has an hindex of 101, co-authored 871 publications receiving 46199 citations. Previous affiliations of Giovanni B. Frisoni include Geneva College & University of Rome Tor Vergata.
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White matter lesions in the elderly: Pathophysiological hypothesis on the effect on brain plasticity and reserve
TL;DR: Recent data suggesting that WMLs might affect brain function through impairment of brain plasticity and reserve are reviewed, suggesting inability of the brain to respond to interventions such as psychotropic drug medications or rehabilitative interventions.
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Reactivity of Cortical Alpha Rhythms to Eye Opening in Mild Cognitive Impairment and Alzheimer's Disease: an EEG Study
Claudio Babiloni,Roberta Lizio,Fabrizio Vecchio,Giovanni B. Frisoni,Michela Pievani,Cristina Geroldi,Fracassi Claudia,Raffaele Ferri,Bartolo Lanuzza,Paolo Maria Rossini +9 more
TL;DR: The continuum across amnesic MCI and mild AD status is related to an impaired reactivity of cortical neuronal synchronization to eyes opening at alpha rhythms, reflecting another aspect of the impairment of cortical neural synchronization.
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Diagnostic accuracy of markers for prodromal Alzheimer’s disease in independent clinical series
Annapaola Prestia,Anna Caroli,Karl Herholz,Eric M. Reiman,Kewei Chen,William J. Jagust,Giovanni B. Frisoni +6 more
TL;DR: To capitalize on data from different clinical series to compare sensitivity and specificity of individual biomarkers for predicting mild cognitive impairment (MCI) progression to Alzheimer's disease (AD).
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Prevention trials in Alzheimer's disease: an EU-US task force report.
Bruno Vellas,Paul S. Aisen,Cristina Sampaio,Maria C. Carrillo,Philip Scheltens,Bruno Scherrer,Giovanni B. Frisoni,Michael W. Weiner,Lon S. Schneider,Serge Gauthier,Christine C Gispen de Wied,Suzanne Hendrix,Howard Feldman,Howard Feldman,Jesse M. Cedarbaum,Ronald C. Petersen,Eric Siemers,Sandrine Andrieu,David Prvulovic,Jacques Touchon,Harald Hampel +20 more
TL;DR: This position paper thoroughly analyzes prerequisites for successful preventative trials inAD and concludes with concrete recommendations on biomarkers, statistical tools and other variables important for improved study designs suitable for preventative as well as for early therapeutic interventional trials in AD.
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Cortical sources of resting state EEG rhythms are sensitive to the progression of early stage Alzheimer's disease
Claudio Babiloni,Roberta Lizio,Claudio Del Percio,Nicola Marzano,Andrea Soricelli,Elena Salvatore,Raffaele Ferri,Filomena I.I. Cosentino,Gioacchino Tedeschi,Patrizia Montella,Silvia Marino,Simona De Salvo,Guido Rodriguez,Flavio Nobili,Fabrizio Vernieri,Francesca Ursini,Ciro Mundi,Jill C. Richardson,Giovanni B. Frisoni,Paolo Maria Rossini +19 more
TL;DR: The results suggest that the resting state EEG sources were sensitive, at least at group level, to the cognitive decline occurring in the mild AD group over a one-year period, and might represent cost-effective and non-invasive markers with which to enrich cohorts of AD patients that decline faster for clinical studies.