G
Gonçalo R. Abecasis
Researcher at University of Michigan
Publications - 629
Citations - 271012
Gonçalo R. Abecasis is an academic researcher from University of Michigan. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 179, co-authored 595 publications receiving 230323 citations. Previous affiliations of Gonçalo R. Abecasis include Johns Hopkins University School of Medicine & Wellcome Trust Centre for Human Genetics.
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Journal ArticleDOI
A Sardinian founder mutation in glycoprotein Ib platelet subunit beta (GP1BB) that impacts thrombocytopenia.
Fabio Busonero,Maristella Steri,Valeria Orrù,Gabriella Sole,Stefania Olla,Michele Marongiu,Andrea Maschio,Carlo Sidore,Sandra Lai,Antonella Mulas,Magdalena Zoledziewska,Matteo Floris,Mauro Pala,Paola Forabosco,Isadora Asunis,Maristella Pitzalis,Francesca Deidda,Marco Masala,Cristian Antonio Caria,Susanna Barella,Gonçalo R. Abecasis,David Schlessinger,Serena Sanna,Edoardo Fiorillo,Francesco Cucca +24 more
TL;DR: A risk-stratified comparison of survival and outcomes data among disease subgroups among Mayo clinic patients with myeloproliferative neoplasms and hypomethylating agents in combination with venetoclax for acute myeloid leukemia is presented.
Journal Article
Genome-wide association scans identify novel loci that influence lipid levels and risk of coronary artery disease
Samer S. Najjar,Cristen J. Willer,Serena Sanna,Anne U. Jackson,Angelo Scuteri,Robert Clarke,Pilar Galan,Pierre Meneton,Diana Zelenika,Jouko Sundvall,R M Watanabe,A. R. Shuldiner,Rory Collins,Richard N. Bergman,Manuela Uda,J. Tuomilehto,F. S. Collins,G M Lathrop,Boehnke M,David Schlessinger,Gonçalo R. Abecasis,Antonio Cao,Karen L. Mohlke,Edward G. Lakatta +23 more
Journal ArticleDOI
358 Large scale meta-analysis characterizes genetic architecture for common psoriasis-associated variants
Lam C. Tsoi,Philip E. Stuart,Chao Tian,Johann E. Gudjonsson,E. al,David A. Hinds,Raji R. Nair,Gonçalo R. Abecasis,James T. Elder +8 more
Journal ArticleDOI
Sparse Allele Vectors and the Savvy Software Suite.
TL;DR: The sparse allele vectors (SAV) file format as mentioned in this paper is an efficient storage format for large-scale DNA variation data and is designed for high throughput association analysis by leveraging techniques for fast deserialization of data into computer memory.
Posted ContentDOI
A scalable Bayesian method for integrating functional information in genome-wide association studies
TL;DR: A novel Bayesian hierarchical model to account for linkage disequilibrium (LD) and multiple functional annotations in GWAS is proposed, paired with an expectation-maximization Markov chain Monte Carlo (EM-MCMC) computational algorithm to jointly analyze genome-wide variants.