G
Gordon H. Guyatt
Researcher at McMaster University
Publications - 1749
Citations - 262329
Gordon H. Guyatt is an academic researcher from McMaster University. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 231, co-authored 1620 publications receiving 228631 citations. Previous affiliations of Gordon H. Guyatt include Memorial Sloan Kettering Cancer Center & Cayetano Heredia University.
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Journal ArticleDOI
Diagnosis of ventilator-associated pneumonia in critically ill adult patients-a systematic review and meta-analysis.
Shannon M. Fernando,Alexandre Tran,Wei Cheng,Michael Klompas,Michael Klompas,Kwadwo Kyeremanteng,Kwadwo Kyeremanteng,Sangeeta Mehta,Shane W. English,Shane W. English,John Muscedere,Deborah J. Cook,Antoni Torres,Otavio T. Ranzani,Alison Fox-Robichaud,Waleed Alhazzani,Laveena Munshi,Gordon H. Guyatt,Bram Rochwerg +18 more
TL;DR: Classic clinical indicators had poor accuracy for diagnosis of VAP and reliance upon these indicators in isolation may result in misdiagnosis and potentially unnecessary antimicrobial use.
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Application of minimal important differences in degenerative knee disease outcomes: a systematic review and case study to inform BMJ Rapid Recommendations
Tahira Devji,Gordon H. Guyatt,Lyubov Lytvyn,Romina Brignardello-Petersen,Romina Brignardello-Petersen,Farid Foroutan,Farid Foroutan,Behnam Sadeghirad,Behnam Sadeghirad,Rachelle Buchbinder,Rudolf W. Poolman,Ian A. Harris,Alonso Carrasco-Labra,Alonso Carrasco-Labra,Reed A C Siemieniuk,Reed A C Siemieniuk,Per Olav Vandvik +16 more
TL;DR: The most credible anchor-based minimal important differences (MIDs) for patient important outcomes in patients with degenerative knee disease are identified to inform BMJ Rapid Recommendations for arthroscopic surgery versus conservative management Design Systematic review.
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Education, ethics, and end-of-life decisions in the intensive care unit
Lesley Stevens,Deborah J. Cook,Gordon H. Guyatt,Lauren Griffith,Steven Walter,Joseph McMullin +5 more
TL;DR: Experiential, case-based, patient-centered curricula are associated with resident confidence in withdrawal of life support decisions in the intensive care unit.
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Patient-reported outcomes in meta-analyses – Part 1: assessing risk of bias and combining outcomes
Bradley C. Johnston,Donald L. Patrick,Jason W. Busse,Holger J. Schünemann,Arnav Agarwal,Gordon H. Guyatt +5 more
TL;DR: The objectives of this paper are to describe PROs and why they are important for health care decision-making, illustrate the key risk of bias issues that systematic reviewers should consider and provide guidance for combining outcomes.
Journal ArticleDOI
Severity of Hypoxemia and Effect of High-Frequency Oscillatory Ventilation in Acute Respiratory Distress Syndrome
Maureen O. Meade,Duncan Young,Steven E. Hanna,Qi Zhou,Thomas E. Bachman,Casper W. Bollen,Arthur S. Slutsky,Sarah E Lamb,Neill K. J. Adhikari,Spyros D. Mentzelopoulos,Deborah J. Cook,Sachin Sud,Roy G. Brower,B. Taylor Thompson,Sanjoy Shah,Alex Stenzler,Gordon H. Guyatt,Niall D. Ferguson +17 more
TL;DR: HFOV increases mortality for most patients with ARDS but may improve survival among patients with severe hypoxemia on conventional mechanical ventilation, and the possibility of decreased mortality in patients with very severe ARDS.