G
Gordon H. Guyatt
Researcher at McMaster University
Publications - 1749
Citations - 262329
Gordon H. Guyatt is an academic researcher from McMaster University. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 231, co-authored 1620 publications receiving 228631 citations. Previous affiliations of Gordon H. Guyatt include Memorial Sloan Kettering Cancer Center & Cayetano Heredia University.
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Randomized trials in oncology stopped early for benefit.
TL;DR: Had this trial been stopped early and its results used to justify an additional course of consolidation chemotherapy, subsequent patients with acute myeloid leukemia would have been exposed to a costly, potentially toxic and ineffective therapy.
Journal ArticleDOI
The Impact of Nocturia on Falls and Fractures: A Systematic Review and Meta-Analysis
Jori S. Pesonen,Robin W.M. Vernooij,Rufus Cartwright,Rufus Cartwright,Yoshitaka Aoki,Arnav Agarwal,Altaf Mangera,Alayne D. Markland,Alayne D. Markland,Johnson F. Tsui,Henrikki Santti,Tomas L. Griebling,Alexey E. Pryalukhin,Jarno Riikonen,Riikka M. Tähtinen,Camille P. Vaughan,Camille P. Vaughan,Theodore M. Johnson,Theodore M. Johnson,Diane Heels-Ansdell,Gordon H. Guyatt,Kari A.O. Tikkinen +21 more
TL;DR: A systematic review and meta-analysis to evaluate the association between nocturia with falls and fractures, both as a prognostic and causal risk factor and rated the quality of evidence as moderate for falls and low for fractures, and as very low as a cause of falls/fractures.
Journal ArticleDOI
Secondary versus primary closure techniques for the prevention of postoperative complications following removal of impacted mandibular third molars: a systematic review and meta-analysis of randomized controlled trials.
Alonso Carrasco-Labra,Romina Brignardello-Petersen,Nicolás Yanine,Ignacio Araya,Gordon H. Guyatt +4 more
TL;DR: Differences between primary and secondary closure techniques after impacted mandibular third molar extraction are likely to be small and available evidence provides only low confidence in the effect estimates.
Journal ArticleDOI
A systematic review of contemporary trials of anticoagulants in orthopaedic thromboprophylaxis: suggestions for a radical reappraisal.
Noel C. Chan,Deborah M. Siegal,Mandy N. Lauw,Jeffrey S. Ginsberg,John W. Eikelboom,John W. Eikelboom,Gordon H. Guyatt,Jack Hirsh +7 more
TL;DR: It is proposed that approaches that minimize bleeding without substantially reducing efficacy merit investigation, particularly if improvement in surgical and perioperative care have also resulted in falling baseline patient important VTE rates independent of anticoagulant use.
Journal ArticleDOI
Delays in hospital admissions in patients with fractures across 18 low-income and middle-income countries (INORMUS): a prospective observational study.
Panthea Pouramin,Chuan Silvia Li,Jason W. Busse,Sheila Sprague,Philip J. Devereaux,Philip J. Devereaux,Jagnoor Jagnoor,Rebecca Ivers,Rebecca Ivers,Mohit Bhandari,Gordon H. Guyatt,Brad Petrisor,Lehana Thabane,Respicious L. Boniface,Bruce D. Browner,Fernando de la Huerta,Rebecca Ivers,Theodore Miclau,Paul J Moroz,Andrew N. Pollak,Gerard P. Slobogean,Parag Sancheti,Emil H. Schemitsch,Junlin Zhou,Paula McKay,Raman Mundi,Nathan N O'Hara,Diane Heels-Ansdell,Lisa Buckingham,Nicole Simunovic,Robyn Norton,Jing Zhang,Maoyi Tian,Soumyadeep Bhaumik,Samina Parveen,Saam Morshed,Madeline C MacKechnie,Yang Liu,Yanrui Zhao,Junfei Li,Haoran Zhang,Zhentao Zhang,Wei Zhang,Tao Guo,Guang Chen,Zichao Jia,Jianzhong Yang,Lixing Kang,Peng Zhang,Haoqing Ma,Donghai Liu,Yinghua Ma,Yanguo Qin,Jincheng Wang,He Liu,Xinlong Ma,Jianxiong Ma,Haobo Jia,Shuangshuang Cui,Zhihu Zhao,Lin Fu,Hongqiang Jiang,Jianwei Lv,Sanbao Hu,Yongwei Wang,Mingyao Sun,Shuqing Tao,Baochang Qi,Ming Gao,Bo Wu,Chunsheng Zhi,Ben Xing,Jun Yang,Wenjie Dai,Duo Lu,Shisheng He,Xinyu Cai,Gejun Liu,Gang Rui,Baoshan Hu,Pingfang Shi,Hua Chen,Te Wang,Qingqing Wang,Linzhen Xie,Huanguang Xie,Tony Mutanda,Juliet Ntuulo,Flavia Lubega,Gayita Teddy Tracy,Kayondo Zaitun,Sylvester Ndayisaba,Titus Amone,Samuel Remmy Odong,Mark Lutomia,Caesar Okatch,Thomas Bitok,Alexander Kiambuthi,Fred Mathew Toboso Otsyeno,PG Jani,Vincent Muoki Mutiso,John Eo Ating'a,Peter Kavoo Kilonzo,James Muoki,Makena Mbogori,Joan Wambui Wambugu,Dorothy Torutt,Christopher Odok,Elisha Ngetich,Dean Otsyeno,Juma Wakhayanga,Desmond Nzioka,Deogracia Owende,Ruth Lucinde,Brian Ngure Kariuki,Dennis Kinyua,Maureen Kamau,Maureen Mwancha,Mellany Murgor,Marilyn Nyabuti,Rita Njoki,Patricia Wanza,Abraham Odongo,Paul Marealle,Athman Wanini,Marwa Elisha,Damas Zumbulu,Pariyo Bonane Godfrey,Benjamin Mukulu Ndeleva,Murila Johnson,Moses Kimani,Kinuthia Gichui,Rogers Joachin Temu,Angela Neofitus Mselle,Ancelimu Rafael Kimario,Mmampapatla Thomas Ramokgopa,Gregory Bodley Firth,Anna Grisillo Biscardi,Machuene Ananias Poopedi,Johan Moolman,Brenda Milner,Matimba Lenny Maluleke,Maxwell Jingo,Susan van Deventer,Timothy Pikor,Ravi Bhaga,Michael Mara,Geoffrey Chege Mwangi,Anthony Muchiri Maina,David Wamae Gicheru,Carol Mwangi,Isaac Kingori Wangai,Peter Watson Maina,Ezra Mitei Kiptoo,Olufemi Olukemi Temiloluwa,Adeyeye Adeolu Ikechukwu,Ige Oluwole Olugbenga,Ojodu Ishaq Bamidele,Oladimeji Oladipupo Akanbi,Panchu Subramanian,Olivia L Mosweu,Samuel Hailu,Geletaw Tessema,Bahiru Bezabih,Birhanu Ayana,Hiwot Hailu,Betelhem Zewdneh,Hana Tesfaye,Sosena Tadesse,Dominic Konadu-Yeboah,Vincent Ativor,Peter Konadu,Dominic Awariyah,Raphael Quartey,Raphael Kumah-Ametepey,Osman Saani,Robert Ekow Quansah,Paa Kwesi Baidoo,Peter Trafton,David Anyitey-Korkor,Michael Leat,Johnny Sobotie,Godwin Opuni,Kwasi Kusi,Twimasi Baah,Paul Okyere,Bernice Mensah,Doris Akuoko Sarpong,Felicia Agbenorwu,Phyllis Osei-Donkor,Priscilla Opoku,Michael Segbefia,Gerald Chukwuemeka Oguzie,Emmanuel Chino Iyidobi,Cajetan Uwatoronye Nwadinigwe,Sharon Amarachi Uloma Oguzie,Emina Bami Kesiena,Henry Ndasi,Nietiayurk Aminake Ghislain,Mala Irine Shey,Ikose John Nanje,Ashok Shyam,Madhav Pandurang Borate,Sampat Dumbre Patil,Sachin Karkamakar,Shailesh Patil,Abhijeet Ranaware,Shadab Tamboli,Manish Gandhalikar,Rohini Tupe,Vishal Chaudhari,Avanti Joshi,Sanjay Patil,Mohit Madhukar Dalwekar,Tejas Gandhi,Chintamani Latkar,Gopal Pundkare,Sandeep Shrivastava,Pradeep K Singh,Sanjay Deshpande,Sumit Baheti,Ravi Mittal,Vijay Sharma,Vinoo Mathew Cherian,Thilak S. Jepegnanam,V.T.K. Titus,Manasseh Nithyananth,P. R. J. V. C. Boopalan,Viju Daniel Varghese,Justin Arockiaraj,Anupam Mahajan,Bobby John,Ritesh Arvind Pandey,Jeewan S Prakash,Valsamma Abraham,Arti Rajkumar,Harvinder Singh Chhabra,Rajesh Sharawat,Ritabh Kumar,Pushkar Chawla,Rashmi Yadav,Rajagopalan N Iyer,Naveen V. Nair,Rajkumar S Amaravathi,Srinivasalu Santhanagopa,Anoop Pilar,Keith Behram Tamboowala,Mandeep S Dhillon,Sarvdeep Singh Dhatt,Asolie Chase,Neel M Bhavsar,Rameez Musa,Darshan Shah,Sunil Chodavadiyah,Pankaj G Patel,Raja Irfan Qadir,Syed Imran Bukhari,Khushnood Ali Baz,Subin Byanjankar,Ruban Raj Joshi,Rajeev Dwivedi,Jay Raj Sharma,La Ngoc Quang,Nguyen Duc Chinh,Vu Bao Hong,Paphon Sa-ngasoongsong,Noratep Kulachote,Norachart Sirisreetreerux,Wanjak Pongsamakthai,Irewin Alagar Tabu,Paula Veronica Reyes,Iardinne Caiquep,Joni Mitchell Robles Bituin,Jenna González,Mohammadreza Golbakhsh,Mashyaneh Haddadi,Soheil Saadat,Mohammadreza Zafarghandi,Clotilde Fuentes Orozco,José de Jesús Martínez Ruíz,Gustavo Armando Tafoya Arreguin,César Eduardo Pinedo Flores,Irydia Guadalupe Pellegrini Verduzco,Miguel Oscar Hernandez Camacho,Diego Abraham Estrada Téllez,Rodrigo Salcedo López,Ileana Guadalupe Canales Navarro,Mizael Dennis Pérez,Daniel de Jesús Enciso Carrillo,Paola Alejandra Álvarez López,Adán Cervantes Gómez,Fátima Nohemí Franco Bravo,Eugenia de los Ángeles Reyes Arias,Igor A. Escalante Elguezabal,Ennio Antonio Rizzo,Jean Michel Hovsepian,Victor Rodriguez,Manuel Malaret Baldo,Andres Serrano,Carlos G. Sanchez Valenciano,Edgar Efren Mercado Salcedo,Fryda Medina,Fernando Bidolegui,Sebastian Pereira,Gerardo Aguilar,Jorge Rubio-Avila,William Dias Belangero,José Ricardo Lenzi Mariolani,Bruno Livani,André Lugnani,Felipe Rossi,Angela Katayama,Fernando Baldy,Vinícius Ynoe de Moraes,Fabricio Fogagnolo,Kodi Edson Kojima,Jorge dos Santos Silva,Marco Kawamura Demange,Fernando Brandão de Andrade-Silva,Adriana Carvalho Gomes da Silva,Nelson Elias,Dino Aguilar Martinez,Fernando Contreras,Mario Garuz,Jose Eduardo Quintero,Gavino Merchan,Christian M. Lozano Lurita,Aturo D. Torres Manrique,Jorge Hurtado Fernandez,Sergio Iriarte Vincenti,Alfredo Pozzo Bobarin,Dalton Salinas Sanchez,Julio Segovia Altieri,Diego Almada,Derlis Bogado,Carlos Coronel,Cristian Boveda,Victor del Valle,Carlos Montiel,Nelson Marin,Antonio Barquet,Daniel Rienzi,Carlos Amanquez,Georges Beauvoir,Iván J Salce Cutipa,José Eduardo Grandi Ribeiro,José María Jiménez Ávila,Luis Padilla,Hernando Cuevas Ochoa,Hernando Cuevas Cano,Adriana Vaca González,Nubia Itzel Gonzalez Gutierrez,Victor Espinola +352 more
TL;DR: In low-income and middle-income countries, timely hospital admission remains largely inaccessible, especially among patients with open fractures, and reducing hospital-based delays in receiving care is a priority.