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Gordon H. Guyatt

Researcher at McMaster University

Publications -  1749
Citations -  262329

Gordon H. Guyatt is an academic researcher from McMaster University. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 231, co-authored 1620 publications receiving 228631 citations. Previous affiliations of Gordon H. Guyatt include Memorial Sloan Kettering Cancer Center & Cayetano Heredia University.

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Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial

Flávia Kessler Borges, +504 more
- 29 Feb 2020 - 
TL;DR: Among patients with a hip fracture, accelerated surgery did not significantly lower the risk of mortality or a composite of major complications compared with standard care.
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Methodologic discussions for using and interpreting composite endpoints are limited, but still identify major concerns.

TL;DR: In this article, the authors investigated the rationale, potential problems and solutions of using composite endpoints (CEPs) for the assessment of intervention effects and concluded that the risk of misinterpretation when heterogeneity among components with respect to either patient importance or magnitude of treatment effects was the most salient disadvantage.
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Assessing Clinical Significance in Measuring Oncology Patient Quality of Life: Introduction to the Symposium, Content Overview, and Definition of Terms

TL;DR: It is hoped that this series of articles will serve as a resource for individuals conducting cancer QOL research and for clinicians considering incorporation of QOL assessment in the treatment of patients with neoplastic diseases.
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A meta-analysis of nocturnal noninvasive positive pressure ventilation in patients with stable COPD

TL;DR: This meta-analysis of 3 months of NIPPV in patients with stable COPD showed that ventilatory support did not improve lung function, gas exchange, or sleep efficiency; the high upper limit of the confidence interval for the 6MWD suggested that some people do improve their walking distance.