G
Gordon H. Guyatt
Researcher at McMaster University
Publications - 1749
Citations - 262329
Gordon H. Guyatt is an academic researcher from McMaster University. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 231, co-authored 1620 publications receiving 228631 citations. Previous affiliations of Gordon H. Guyatt include Memorial Sloan Kettering Cancer Center & Cayetano Heredia University.
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Journal ArticleDOI
Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial.
Mark Crowther,Deborah J. Cook,Gordon H. Guyatt,Nicole Zytaruk,Ellen McDonald,David Williamson,Martin Albert,Peter Dodek,Simon Finfer,Shirley Vallance,Diane Heels-Ansdell,Lauralyn McIntyre,Sangeeta Mehta,Francois Lamontagne,John Muscedere,Michael J. Jacka,Olivier Lesur,Jim Kutsiogiannis,Jan O. Friedrich,James R. Klinger,Ismael Qushmaq,Lisa Burry,Kosar Khwaja,Jo-Ann I. Sheppard,Theodore E. Warkentin +24 more
TL;DR: The need for further research to improve the assessment of PTP scoring of HIT for critically ill patients is highlighted, as well as the need for more information on how to identify patients at low risk for HIT.
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Assessing disease activity in ulcerative colitis: patients or their physicians?
Dan Turner,Anne M. Griffiths,David R. Mack,Anthony R. Otley,Cynthia H Seow,A. Hillary Steinhart,Mark S. Silverberg,Jeffrey S. Hyams,Gordon H. Guyatt +8 more
TL;DR: For indirect measurement of biological activity on the basis of symptoms and signs, clinician assessments are superior to those of patients, and direct measurement of disease activity provide complementary information in clinical research.
Journal ArticleDOI
Incidence of Clinically Important Bleeding in Mechanically Ventilated Patients
TL;DR: The presence of a coagulopathy is a powerful independent risk factor for overt bleeding in this population of critically ill medical and surgical patients, and the risk of overt bleeding also increases with the number of days of positive occult bleeding.
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Risk Factors for 1-Year Graft Loss After Kidney Transplantation: Systematic Review and Meta-Analysis.
Farid Foroutan,Erik Loewen Friesen,Kathryn Elizabeth Clark,Shahrzad Motaghi,Roman E Zyla,Yung Lee,Rakhshan Kamran,Emir Ali,Mitch L. De Snoo,Ani Orchanian-Cheff,Christine Ribic,Darin Treleaven,Gordon H. Guyatt,Maureen O. Meade +13 more
TL;DR: Recipient age, donor age, standard versus extended criteria donor, living versus deceased donor, HLA mismatch, and delayed graft function all predicted 1-year graft survival and the effect of each risk factor is small.
Journal ArticleDOI
Completion and Publication Rates of Randomized Controlled Trials in Surgery: An Empirical Study.
Rachel Rosenthal,Benjamin Kasenda,Salome Dell-Kuster,Erik von Elm,John J. You,Anette Blümle,Yuki Tomonaga,Ramon Saccilotto,Alain Amstutz,Theresa Bengough,Joerg J Meerpohl,Mihaela Stegert,Kari A.O. Tikkinen,Ignacio Neumann,Ignacio Neumann,Alonso Carrasco-Labra,Alonso Carrasco-Labra,Markus Faulhaber,Markus Faulhaber,Sohail M. Mulla,Dominik Mertz,Elie A. Akl,Elie A. Akl,Dirk Bassler,Jason W. Busse,Jason W. Busse,Ignacio Ferreira-González,Francois Lamontagne,Alain J Nordmann,Viktoria Gloy,Kelechi K Olu,Heike Raatz,Lorenzo Moja,Shanil Ebrahim,Stefan Schandelmaier,Xin Sun,Xin Sun,Per Olav Vandvik,Bradley C. Johnston,Martin A. Walter,Martin A. Walter,Bernard Burnand,Matthias Schwenkglenks,Lars G. Hemkens,Heiner C. Bucher,Gordon H. Guyatt,Matthias Briel +46 more
TL;DR: Discontinuation and nonpublication rates were substantial in surgical RCTs and trial discontinuation was strongly associated with non publication, which needs to be taken into account when interpreting surgical literature.