G
Gordon H. Guyatt
Researcher at McMaster University
Publications - 1749
Citations - 262329
Gordon H. Guyatt is an academic researcher from McMaster University. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 231, co-authored 1620 publications receiving 228631 citations. Previous affiliations of Gordon H. Guyatt include Memorial Sloan Kettering Cancer Center & Cayetano Heredia University.
Papers
More filters
Journal ArticleDOI
Deep venous thrombosis in medical-surgical critically ill patients: prevalence, incidence, and risk factors.
Deborah J. Cook,Mark Crowther,Maureen O. Meade,Christian Rabbat,Lauren Griffith,David Schiff,William Geerts,Gordon H. Guyatt +7 more
TL;DR: Despite universal thromboprophylaxis, medical-surgical critically ill patients remain at risk for lower extremity deep venousThrombosis, and further research is needed to evaluate the risks and benefits of more intense venous thromboembolism prophylaxis.
Journal ArticleDOI
Validity of composite end points in clinical trials.
Victor M. Montori,Gaietà Permanyer-Miralda,Ignacio Ferreira-González,Jason W. Busse,Valeria Pacheco-Huergo,Dianne Bryant,Jordi Alonso,Elie A. Akl,Antònia Domingo-Salvany,Edward J Mills,Ping Wu,Holger J. Schünemann,Roman Jaeschke,Gordon H. Guyatt +13 more
TL;DR: In this article, a strategy to interpret the results of clinical trials when investigators measure the effect of treatment on an aggregate of end points of varying importance is provided.
Journal ArticleDOI
Predicting Success in Weaning From Mechanical Ventilation
Maureen O. Meade,Gordon H. Guyatt,Deborah J. Cook,Lauren Griffith,Tasnim Sinuff,Carmen Kergl,Jordi Mancebo,Andrés Esteban,Scott K. Epstein +8 more
TL;DR: In this article, the authors identified 65 observational studies of weaning predictors that had been reported in 70 publications, and grouped predictors with similar names but different thresholds, and the following predictors met their relevance criteria: heterogeneous populations, 51; COPD patients, 21; and cardiovascular ICU patients, 45.
Journal ArticleDOI
Assessing the Minimal Important Difference in Symptoms: A Comparison of Two Techniques
TL;DR: Observations support the role of the Chronic Respiratory Questionnaire for measuring patient's symptoms, the validity of the approach for assessing the MID, and an estimate on the order of 0.5 as the threshold for this particular health status measure.
Journal ArticleDOI
Should Unpublished Data Be Included in Meta-analyses?: Current Convictions and Controversies
Deborah J. Cook,Gordon H. Guyatt,G. Ryan,J Clifton,Lisa Buckingham,Andrew R. Willan,William McIlroy,Andrew D Oxman +7 more
TL;DR: This paper conducted a literature review and a cross-sectional survey to identify the extent to which meta-analyses currently include unpublished data and whether editors, meta-analysts, and methodologists believe unpublished material should be included.