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Hayes McDonald

Researcher at Vanderbilt University

Publications -  6
Citations -  1452

Hayes McDonald is an academic researcher from Vanderbilt University. The author has contributed to research in topics: MALDI imaging & Histone H1. The author has an hindex of 5, co-authored 6 publications receiving 1316 citations. Previous affiliations of Hayes McDonald include Vanderbilt University Medical Center.

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Journal ArticleDOI

Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans.

Brian J. Haas, +102 more
- 17 Sep 2009 - 
TL;DR: The sequence of the P. infestans genome is reported, which at ∼240 megabases (Mb) is by far the largest and most complex genome sequenced so far in the chromalveolates and probably plays a crucial part in the rapid adaptability of the pathogen to host plants and underpins its evolutionary potential.
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Dedifferentiation of patient‐derived glioblastoma multiforme cell lines results in a cancer stem cell‐like state with mitogen‐independent growth

TL;DR: The results indicate that iGSCs may help to understand CSC physiology and lead to development of potential therapeutic interventions aimed at differentiating tumour cells to render them more sensitive to chemotherapy or other standard agents.
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Short Forms of Ste20-related Proline/Alanine-rich Kinase (SPAK) in the Kidney Are Created by Aspartyl Aminopeptidase (Dnpep)-mediated Proteolytic Cleavage

TL;DR: It is demonstrated that kidney lysate possesses proteolytic cleavage activity toward SPAK, and the presence of the protease was verified in the active fractions, and recombinant aspartyl aminopeptidase recapitulated the cleavage pattern observed with kidneyLysate.
Journal ArticleDOI

Altered Expression of Nuclear and Cytoplasmic Histone H1 in Pulmonary Artery and Pulmonary Artery Smooth Muscle Cells in Patients with IPAH

TL;DR: In this article, the authors used histology-based Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS) to identify proteins that may be associated with the structural changes in the pulmonary arterial walls of patients with idiopathic pulmonary hypertension.