J
Jaring Schreuder
Researcher at Walter and Eliza Hall Institute of Medical Research
Publications - 13
Citations - 1172
Jaring Schreuder is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Haematopoiesis & Progenitor cell. The author has an hindex of 7, co-authored 12 publications receiving 841 citations. Previous affiliations of Jaring Schreuder include University of Queensland & University of Melbourne.
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Journal ArticleDOI
Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow
Andreas Schlitzer,V. Sivakamasundari,Jinmiao Chen,Hermi Sumatoh,Jaring Schreuder,Josephine Lum,Benoit Malleret,Sanqian Zhang,Anis Larbi,Francesca Zolezzi,Laurent Rénia,Michael Poidinger,Shalin H. Naik,Evan W. Newell,Paul Robson,Florent Ginhoux +15 more
TL;DR: This work found that transcriptional signatures of the cDC1 and cDC2 lineages became evident at the single-cell level from the CDP stage, and identified Siglec-H and Ly6C as lineage markers that distinguished pre-DC subpopulations committed to the c DC1 lineage (SigleC-H−Ly6C− pre- DCs) or c DC2 lineage (CDC2 lineage).
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Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
TL;DR: As shown using clonal assays, the mouse HSC population undergoes quantitative as well as qualitative changes with age, including lineage differentiation, HSC pool size, marrow-homing efficiency, and self-renewal.
Journal ArticleDOI
Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer.
Delphine Merino,Tom S. Weber,Tom S. Weber,Antonin Serrano,Antonin Serrano,François Vaillant,François Vaillant,Kevin H. Liu,Kevin H. Liu,Bhupinder Pal,Bhupinder Pal,L Di Stefano,Jaring Schreuder,Jaring Schreuder,Dawn S. Lin,Dawn S. Lin,Yunshun Chen,Yunshun Chen,Marie Liesse Asselin-Labat,Marie Liesse Asselin-Labat,Ton N. Schumacher,Daniel L Cameron,Gordon K. Smyth,Gordon K. Smyth,Anthony T. Papenfuss,Geoffrey J. Lindeman,Jane E. Visvader,Jane E. Visvader,Shalin H. Naik,Shalin H. Naik +29 more
TL;DR: In this article, cellular barcoding of two treatment-naive TNBC patient-derived xenografts (PDXs) was used to track the spatio-temporal fate of thousands of barcoded clones in primary tumors, and their metastases.
Journal ArticleDOI
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
Nicolas Jacquelot,Nicolas Jacquelot,Nicolas Jacquelot,Cyril Seillet,Cyril Seillet,Minyu Wang,Minyu Wang,Angela Pizzolla,Angela Pizzolla,Yang Liao,Soroor Hediyeh-Zadeh,Soroor Hediyeh-Zadeh,Sharon Grisaru-Tal,Cynthia Louis,Cynthia Louis,Qiutong Huang,Qiutong Huang,Qiutong Huang,Jaring Schreuder,Fernando Souza-Fonseca-Guimaraes,Carolyn A. de Graaf,Carolyn A. de Graaf,Kevin Y. T. Thia,Sean Macdonald,Mary J Camilleri,Mary J Camilleri,Kylie Luong,Kylie Luong,Shengbo Zhang,Shengbo Zhang,Michael Chopin,Michael Chopin,Tristan Molden-Hauer,Stephen L. Nutt,Stephen L. Nutt,Viktor Umansky,Viktor Umansky,Bogoljub Ciric,Joanna R Groom,Joanna R Groom,Paul S. Foster,Philip M. Hansbro,Philip M. Hansbro,Philip M. Hansbro,Andrew N. J. McKenzie,Daniel H.D. Gray,Daniel H.D. Gray,Andreas Behren,Andreas Behren,Jonathan Cebon,Eric Vivier,Ian P. Wicks,Ian P. Wicks,Ian P. Wicks,Joseph A. Trapani,Joseph A. Trapani,Ariel Munitz,Melissa J. Davis,Melissa J. Davis,Wei Shi,Paul J Neeson,Paul J Neeson,Gabrielle T. Belz,Gabrielle T. Belz,Gabrielle T. Belz +64 more
TL;DR: This paper found that high ILC2 infiltration in human melanoma was associated with a good clinical prognosis and revealed a potential synergistic approach to harness group 2 innate lymphoid cells for antitumor immunotherapies.
Journal ArticleDOI
MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells.
Bilal N. Sheikh,Bilal N. Sheikh,Yuqing Yang,Yuqing Yang,Jaring Schreuder,Jaring Schreuder,Susan K. Nilsson,Susan K. Nilsson,Rebecca A. Bilardi,Rebecca A. Bilardi,Sebastian Carotta,Sebastian Carotta,Helen M. McRae,Helen M. McRae,Donald Metcalf,Anne K. Voss,Anne K. Voss,Tim Thomas,Tim Thomas +18 more
TL;DR: It is established that there are essential differences in HSC requirement for steady-state blood cell production compared with the artificial situation of reconstitution after transplantation into a hemoablated host.