J
Jasper J. Koehorst
Researcher at Wageningen University and Research Centre
Publications - 49
Citations - 1940
Jasper J. Koehorst is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 16, co-authored 42 publications receiving 1418 citations. Previous affiliations of Jasper J. Koehorst include University of Queensland.
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Journal ArticleDOI
RNA Targeting by the Type III-A CRISPR-Cas Csm Complex of Thermus thermophilus
Raymond H.J. Staals,Yifan Zhu,David W. Taylor,Jack E. Kornfeld,Kundan Sharma,Arjan Barendregt,Jasper J. Koehorst,Marnix Vlot,Nirajan Neupane,Koen Varossieau,Keiko Sakamoto,Takehiro Suzuki,Naoshi Dohmae,Shigeyuki Yokoyama,Peter J. Schaap,Henning Urlaub,Albert J. R. Heck,Eva Nogales,Eva Nogales,Eva Nogales,Jennifer A. Doudna,Jennifer A. Doudna,Jennifer A. Doudna,Akeo Shinkai,John van der Oost +24 more
TL;DR: The structure and function of the effector complex of the Type III-A CRISPR-Cas system of Thermus thermophilus: the Csm complex is reported, showing that, like TtCmr, TTCsm cleaves complementary target RNAs at multiple sites.
Journal ArticleDOI
MEMOTE for standardized genome-scale metabolic model testing
Christian Lieven,Moritz Emanuel Beber,Brett G. Olivier,Frank Bergmann,Meriç Ataman,Parizad Babaei,Jennifer A. Bartell,Lars M. Blank,Siddharth Chauhan,Kevin Correia,Christian Diener,Christian Diener,Andreas Dräger,Birgitta E. Ebert,Birgitta E. Ebert,Janaka N. Edirisinghe,José P. Faria,Adam M. Feist,Adam M. Feist,Georgios Fengos,Ronan M. T. Fleming,Beatriz García-Jiménez,Beatriz García-Jiménez,Vassily Hatzimanikatis,Wout van Helvoirt,Wout van Helvoirt,Christopher S. Henry,Henning Hermjakob,Markus J. Herrgård,Ali Kaafarani,Hyun Uk Kim,Zachary A. King,Steffen Klamt,Edda Klipp,Jasper J. Koehorst,Matthias König,Meiyappan Lakshmanan,Dong-Yup Lee,Dong-Yup Lee,Sang Yup Lee,Sang Yup Lee,Sunjae Lee,Sunjae Lee,Nathan E. Lewis,Filipe Liu,Hongwu Ma,Daniel Machado,Radhakrishnan Mahadevan,Paulo Maia,Adil Mardinoglu,Adil Mardinoglu,Gregory L. Medlock,Jonathan M. Monk,Jens Nielsen,Jens Nielsen,Lars K. Nielsen,Lars K. Nielsen,Juan Nogales,Intawat Nookaew,Intawat Nookaew,Bernhard O. Palsson,Bernhard O. Palsson,Jason A. Papin,Kiran Raosaheb Patil,Mark G. Poolman,Nathan D. Price,Osbaldo Resendis-Antonio,Anne Richelle,Isabel Rocha,Isabel Rocha,Benjamin Sanchez,Benjamin Sanchez,Peter J. Schaap,Rahuman S. Malik Sheriff,Saeed Shoaie,Saeed Shoaie,Nikolaus Sonnenschein,Bas Teusink,Paulo Vilaça,Jon Olav Vik,Judith A. H. Wodke,Joana C. Xavier,Qianqian Yuan,Maksim Zakhartsev,Cheng Zhang +84 more
TL;DR: A community effort to develop a test suite named MEMOTE (for metabolic model tests) to assess GEM quality, and advocate adoption of the latest version of the Systems Biology Markup Language level 3 flux balance constraints (SBML3FBC) package as the primary description and exchange format.
Journal ArticleDOI
Reverse Methanogenesis and Respiration in Methanotrophic Archaea.
Peer H. A. Timmers,Cornelia U. Welte,Jasper J. Koehorst,Caroline M. Plugge,Mike S. M. Jetten,Alfons J. M. Stams +5 more
TL;DR: In this review, the reversibility of the methanogenesis pathway and essential differences between ANME and methanogens are described by combining published information with domain based (meta)genome comparison of archaeal methanotrophs and selected archaea.
Journal ArticleDOI
Structure and Activity of the RNA-Targeting Type III-B CRISPR-Cas Complex of Thermus thermophilus
Raymond H.J. Staals,Yoshihiro Agari,Saori Maki-Yonekura,Yifan Zhu,David W. Taylor,David W. Taylor,Esther van Duijn,Arjan Barendregt,Marnix Vlot,Jasper J. Koehorst,Keiko Sakamoto,Akiko Masuda,Naoshi Dohmae,Peter J. Schaap,Jennifer A. Doudna,Jennifer A. Doudna,Jennifer A. Doudna,Albert J. R. Heck,Koji Yonekura,John van der Oost,Akeo Shinkai +20 more
TL;DR: Electron microscopy revealed that the structure of TtCmr resembles a "sea worm" and is composed of a Cmr2-3 heterodimer "tail," a helical backbone of Cmr4 subunits capped by Cmr5 subunits, and a curled "head" containing Cmr1 and Cmr6.
Journal ArticleDOI
A genomic view on syntrophic versus non-syntrophic lifestyle in anaerobic fatty acid degrading communities.
Petra Worm,Jasper J. Koehorst,Michael Visser,Vicente T. Sedano-Núñez,Peter J. Schaap,Caroline M. Plugge,Diana Z. Sousa,Alfons J. M. Stams +7 more
TL;DR: In this article, the authors study from a genome perspective why some micro-organisms are able to grow in syntrophy with methanogens and others are not, and identify two domains with a currently unknown function seem to be associated with the ability of syntrophic growth.