K
Kaixian Chen
Researcher at Chinese Academy of Sciences
Publications - 403
Citations - 11476
Kaixian Chen is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Virtual screening & Chemistry. The author has an hindex of 47, co-authored 380 publications receiving 9209 citations. Previous affiliations of Kaixian Chen include Shanghai University & East China University of Science and Technology.
Papers
More filters
Journal ArticleDOI
Microstructure evolution, mechanical properties, and corrosion behavior of novel (50Zr–50Ti)-xNi ternary alloys
TL;DR: In this paper , a series of (50Zr-50Ti)-xNi alloys were prepared by employing the vacuum arc melting method within a furnace, and the phase composition and microstructure of these alloys are analyzed by performing TEM, XRD measurements and other microscopic analysis methods.
Patent
Substituted flavonoids and preparation method, application and pharmaceutical composition thereof
Hong Liu,Hualiang Jiang,Weiliang Zhu,Mingfang Zheng,Mingyue Zheng,Xiaomin Luo,Jianhua Shen,Kaixian Chen +7 more
TL;DR: In this paper, a substituted flavonoid in formula (I), and pharmaceutically acceptable salt, solvate and hydrate thereof, wherein the definitions of R1-R10, X and Y are described in specification.
Journal ArticleDOI
High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases.
Senhao Xiao,Senhao Xiao,Siqi Guo,Siqi Guo,Jie Han,Yanli Sun,Yanli Sun,Mingchen Wang,Mingchen Wang,Yantao Chen,Xueyu Fang,Xueyu Fang,Feng Yang,Yajuan Mu,Liang Zhang,Yiluan Ding,Naixia Zhang,Hualiang Jiang,Hualiang Jiang,Kaixian Chen,Kaixian Chen,Kehao Zhao,Cheng Luo,Shijie Chen +23 more
TL;DR: In this article, a fluorescence polarization-based "High-Throughput Methyl Reading" (HTMR) assay was developed to implement large-scale compound screening for DNA/RNA methyltransferases and demethylases-DNMTs, TETs, ALKBH5 and METTL3/METTL14.
Journal ArticleDOI
Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancer
Jie Yi Chang,Ruirui Yang,Lifan Claire Chen,Zi-sheng Fan,Jing Zhou,Hao Guo,Yinghui Zhang,Yadan Liu,Guizhen Zhou,Keke Zhang,Kaixian Chen,Hualiang Jiang,Mingyue Zheng,Sulin Zhang +13 more
TL;DR: In this article , the authors propose a method to improve the quality of the images. ǫ 1.1.1 ǒ 2 ǩ 2 Ãǫ
Journal ArticleDOI
Synthesis of 4-Aryl-2(5H)-furanones by Gold(I)-Catalyzed Intramolecular Annulation
TL;DR: In this paper, a novel method that involves intramolecular annulation and a new type of rearrangement has been developed for the synthesis of 4-aryl-2(5H)-furanones.