L
Laure Plantard
Researcher at Friedrich Miescher Institute for Biomedical Research
Publications - 10
Citations - 509
Laure Plantard is an academic researcher from Friedrich Miescher Institute for Biomedical Research. The author has contributed to research in topics: Connexin & Gene. The author has an hindex of 6, co-authored 9 publications receiving 461 citations. Previous affiliations of Laure Plantard include University Hospital of Lausanne & Karolinska Institutet.
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Journal ArticleDOI
Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda
Fabrice Chimienti,Ron C. Hogg,Laure Plantard,Caroline Lehmann,Noureddine Brakch,Judith Fischer,Marcel Huber,Daniel Bertrand,Daniel Hohl +8 more
TL;DR: It is found that SLURP-1 potentiates the human alpha 7 nicotinic acetylcholine receptors that are present in keratinocytes and is likely to be essential for both epidermal homeostasis and inhibition of TNF-alpha release by macrophages during wound healing.
Journal ArticleDOI
PtdIns(3,4,5)P3 is a regulator of myosin-X localization and filopodia formation
Laure Plantard,Antti Arjonen,Antti Arjonen,John G. Lock,Ghasem Nurani,Johanna Ivaska,Johanna Ivaska,Staffan Strömblad +7 more
TL;DR: The results indicate that PtdIns(3,4,5)P3 binding to the Myo10-PH2 domain is involved in Myosin-X trafficking and regulation of filopodia dynamics.
Journal ArticleDOI
SLURP1 Is a Late Marker of Epidermal Differentiation and Is Absent in Mal de Meleda
Bertrand Favre,Laure Plantard,Lorène Aeschbach,Noureddine Brakch,Stéphanie Christen-Zaech,Pierre A. de Viragh,Ann Sergeant,Marcel Huber,Daniel Hohl +8 more
TL;DR: SLURP1 was found to be a marker of late differentiation, predominantly expressed in the granular layer of skin, notably the acrosyringium, suggesting that a simple immunologic test could be used as a rapid screening procedure.
Journal ArticleDOI
Molecular interaction of connexin 30.3 and connexin 31 suggests a dominant-negative mechanism associated with erythrokeratodermia variabilis.
TL;DR: Inhibitor experiments revealed that this interaction begins in the endoplasmic reticulum, which allows a novel molecular explanation for the similarity of EKV phenotypes and provides new insights into epidermal connexin synthesis and polymerization.
Journal ArticleDOI
QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy
Glyn Nelson,Ulrike Boehm,Steve Bagley,Peter Bajcsy,Johanna Bischof,Claire M. Brown,Aurelien Dauphin,Ian M. Dobbie,John E Eriksson,Orestis Faklaris,Julia Fernandez-Rodriguez,Alexia Ferrand,Laurent Gelman,Ali Gheisari,Hella Hartmann,Christian Kukat,Alex Laude,Miso Mitkovski,Sebastian Munck,Alison J. North,Tobias M. Rasse,Ute Resch-Genger,Lucas C Schuetz,Arne Seitz,Caterina Strambio-De-Castillia,Jason R. Swedlow,Ioannis Alexopoulos,Karin Aumayr,Sergiy V. Avilov,Gert-Jan Bakker,Rodrigo R Bammann,Andrea Bassi,Hannes Beckert,Sebastian Beer,Yury Belyaev,Jakob Bierwagen,Konstantin A Birngruber,Manel Bosch,Juergen Breitlow,Lisa A. Cameron,Joe Chalfoun,James J. Chambers,Chieh-Li Chen,Eduardo Conde-Sousa,Alexander D. Corbett,Fabrice P. Cordelières,Elaine Del Nery,Ralf Dietzel,Frank Eismann,Elnaz Fazeli,Andreas Felscher,Hans-Ulrich Fried,Nathalie Gaudreault,Wah Ing Goh,Thomas Guilbert,Roland Hadleigh,Peter Hemmerich,Gerhard A Holst,Michelle S. Itano,Claudia B Jaffe,Helena Jambor,Stuart C Jarvis,Antje Keppler,David Kirchenbuechler,Marcel Kirchner,Norio Kobayashi,Gabriel Krens,Susanne Kunis,Judith Lacoste,Marco Marcello,Gabriel G. Martins,Daniel J Metcalf,Claire A. Mitchell,Joshua Moore,Tobias Mueller,Michael S. Nelson,Stephen Ogg,Shuichi Onami,Alexandra L Palmer,Perrine Paul-Gilloteaux,Jaime A. Pimentel,Laure Plantard,Santosh Podder,Elton Rexhepaj,Arnaud Royon,Markku Saari,Damien Schapman,Vincent Schoonderwoert,Britta Schroth-Diez,Stanley Schwartz,Michael Shaw,Martin Spitaler,Martin T Stoeckl,Damir Sudar,Jeremie Teillon,Stefan Terjung,Roland Thuenauer,Christian D Wilms,Graham D. Wright,Roland Nitschke +99 more
TL;DR: The QUAREP-LiMi initiative as mentioned in this paper aims to improve the overall quality and reproducibility of light microscope image data by introducing broadly accepted standard practices and accurately captured image data metrics.