Karin Aumayr

TL;DR: Three lncRNAs that induce parental-specific silencing show hallmarks indicating that their transcription is more important than their product, indicating a gene silencing mechanism that may be widespread in the mammalian genome, given the abundance of lncRNA transcripts.

TL;DR: CD14 interacts with and is essential for the functions of endosomal TLR7 and TLR9 in mice and acts as a “spatially aggregating force” to spruce up the immune response to chemotherapy.

TL;DR: This work identifies a previously unreported and potentially widespread class of PRE/TREs that switch function by switching the direction of noncoding RNA transcription, allowing regulated inhibition of local PRC2 activity.

TL;DR: The QUAREP-LiMi initiative as mentioned in this paper aims to improve the overall quality and reproducibility of light microscope image data by introducing broadly accepted standard practices and accurately captured image data metrics.

TL;DR: It is demonstrated that secreted ILEI requires site-specific proteolytic maturation into its short form for its tumor-promoting function, which is executed by serine proteases, most efficiently by plasmin.