L
Lindsay P. Cameron
Researcher at University of California, Davis
Publications - 15
Citations - 1053
Lindsay P. Cameron is an academic researcher from University of California, Davis. The author has contributed to research in topics: Hallucinogen & Serotonin transporter. The author has an hindex of 9, co-authored 13 publications receiving 457 citations.
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Journal ArticleDOI
Psychedelics Promote Structural and Functional Neural Plasticity
Calvin Ly,Alexandra C. Greb,Lindsay P. Cameron,Jonathan M. Wong,Eden V. Barragan,Paige C. Wilson,Kyle F. Burbach,Sina Soltanzadeh Zarandi,Alexander Sood,Michael R. Paddy,Whitney C. Duim,Megan Y. Dennis,A. Kimberley McAllister,Kassandra M. Ori-McKenney,John A. Gray,David E. Olson +15 more
TL;DR: It is reported that, like ketamine, serotonergic psychedelics are capable of robustly increasing neuritogenesis and/or spinogenesis both in vitro and in vivo.
Journal ArticleDOI
A non-hallucinogenic psychedelic analogue with therapeutic potential
Lindsay P. Cameron,Robert J. Tombari,Ju Lu,Alexander J. Pell,Zefan Q. Hurley,Yann Ehinger,Maxemiliano V. Vargas,Matthew N. McCarroll,Jack C. Taylor,Douglas Myers-Turnbull,Taohui Liu,Bianca Yaghoobi,Lauren J. Laskowski,Emilie I. Anderson,Guoliang Zhang,Jayashri Viswanathan,Brandon M. Brown,Michelle Tjia,Lee E. Dunlap,Zachary Rabow,Oliver Fiehn,Heike Wulff,John D. McCorvy,Pamela J. Lein,David Kokel,Dorit Ron,Jamie Peters,Yi Zuo,David E. Olson +28 more
TL;DR: This work demonstrates that, through careful chemical design, it is possible to modify a psychedelic compound to produce a safer, non-hallucinogenic variant that has therapeutic potential.
Journal ArticleDOI
Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.
Elizabeth K. Unger,Jacob P. Keller,Michael Altermatt,Ruqiang Liang,Aya Matsui,Chunyang Dong,Olivia J Hon,Zi Yao,Junqing Sun,Samba Banala,Meghan E. Flanigan,David A. Jaffe,Samantha Hartanto,Jane Carlen,Grace O. Mizuno,Phillip M. Borden,Amol V. Shivange,Lindsay P. Cameron,Steffen Sinning,Suzanne M. Underhill,David E. Olson,Susan G. Amara,Duncan Temple Lang,Gary Rudnick,Jonathan S. Marvin,Luke D. Lavis,Henry A. Lester,Veronica A. Alvarez,Andrew J. Fisher,Jennifer A. Prescher,Thomas L. Kash,Vladimir Yarov-Yarovoy,Viviana Gradinaru,Loren L. Looger,Lin Tian +34 more
TL;DR: iSeroSnFR can be used to detect serotonin release in freely behaving mice during fear conditioning, social interaction, and sleep/wake transitions, and it is expected that both machine-learning-guided binding-pocket redesign and iSero SnFR will have broad utility for the development of other sensors and in vitro and in-vivo serotonin detection, respectively.
Journal ArticleDOI
Effects of N, N-Dimethyltryptamine on Rat Behaviors Relevant to Anxiety and Depression.
TL;DR: It is found that while DMT elicits initial anxiogenic responses in several of these paradigms, its long-lasting effects tend to reduce anxiety by facilitating the extinction of cued fear memory, and DMT reduces immobility in the forced swim test, which is a characteristic behavioral response induced by many antidepressants.
Journal ArticleDOI
Chronic, Intermittent Microdoses of the Psychedelic N,N-Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents
Lindsay P. Cameron,Charlie J Benson,Brian C. DeFelice,Oliver Fiehn,Oliver Fiehn,David E. Olson +5 more
TL;DR: It is found that chronic, intermittent, low doses of DMT produced an antidepressant-like phenotype and enhanced fear extinction learning without impacting working memory or social interaction.