Z
Zongli Xu
Researcher at National Institutes of Health
Publications - 94
Citations - 5526
Zongli Xu is an academic researcher from National Institutes of Health. The author has contributed to research in topics: DNA methylation & Cancer. The author has an hindex of 33, co-authored 85 publications receiving 4327 citations. Previous affiliations of Zongli Xu include Research Triangle Park & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies
Zongli Xu,Jack A. Taylor +1 more
TL;DR: A set of web-based SNP selection tools where investigators can specify genes or linkage regions and select SNPs based on GWAS results, linkage disequilibrium (LD), and predicted functional characteristics of both coding and non-coding SNPs is developed.
Journal ArticleDOI
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Bonnie R. Joubert,Janine F. Felix,Paul Yousefi,Kelly M. Bakulski,Allan C. Just,Carrie V. Breton,Sarah E. Reese,Christina A. Markunas,Christina A. Markunas,Rebecca C Richmond,Cheng-Jian Xu,Leanne K. Küpers,Sam S. Oh,Cathrine Hoyo,Olena Gruzieva,Cilla Söderhäll,Lucas A. Salas,Nour Baïz,Hongmei Zhang,Johanna Lepeule,Carlos Ruiz,Symen Ligthart,Tianyuan Wang,Jack A. Taylor,Liesbeth Duijts,Gemma C Sharp,Soesma A Jankipersadsing,Roy Miodini Nilsen,Ahmad Vaez,Ahmad Vaez,M. Daniele Fallin,Donglei Hu,Augusto A. Litonjua,Bernard F. Fuemmeler,Karen Huen,Juha Kere,Inger Kull,Monica Cheng Munthe-Kaas,Ulrike Gehring,Mariona Bustamante,Marie José Saurel-Coubizolles,Bilal M. Quraishi,Jie Ren,Jörg Tost,Juan R. González,Marjolein J. Peters,Siri E. Håberg,Zongli Xu,Joyce B. J. van Meurs,Tom R. Gaunt,Marjan Kerkhof,Eva Corpeleijn,Andrew P. Feinberg,Celeste Eng,Andrea A. Baccarelli,Sara E. Benjamin Neelon,Asa Bradman,Simon Kebede Merid,Anna Bergström,Zdenko Herceg,Hector Hernandez-Vargas,Bert Brunekreef,Mariona Pinart,Barbara Heude,Susan Ewart,Jin Yao,Nathanaël Lemonnier,Oscar H. Franco,Michael C. Wu,Albert Hofman,Albert Hofman,Wendy L. McArdle,Pieter van der Vlies,Fahimeh Falahi,Matthew W. Gillman,Lisa F. Barcellos,Ashok Kumar,Ashok Kumar,Ashok Kumar,Magnus Wickman,Magnus Wickman,Stefano Guerra,Marie-Aline Charles,John W. Holloway,Charles Auffray,Henning Tiemeier,George Davey Smith,Dirkje S. Postma,Marie-France Hivert,Brenda Eskenazi,Martine Vrijheid,Hasan Arshad,Josep M. Antó,Abbas Dehghan,Wilfried Karmaus,Isabella Annesi-Maesano,Jordi Sunyer,Akram Ghantous,Göran Pershagen,Nina Holland,Susan K. Murphy,Dawn L. DeMeo,Esteban G. Burchard,Christine Ladd-Acosta,Harold Snieder,Wenche Nystad,Gerard H. Koppelman,Caroline L Relton,Vincent W. V. Jaddoe,Allen J. Wilcox,Erik Melén,Erik Melén,Stephanie J. London +112 more
TL;DR: This large scale meta-analysis of methylation data identified numerous loci involved in response to maternal smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure.
Journal ArticleDOI
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
Nathaniel Rothman,Montserrat Garcia-Closas,Nilanjan Chatterjee,Núria Malats,Xifeng Wu,Jonine D. Figueroa,Francisco X. Real,David Van Den Berg,Giuseppe Matullo,Dalsu Baris,Michael J. Thun,Lambertus A. Kiemeney,Paolo Vineis,Immaculata De Vivo,Demetrius Albanes,Mark P. Purdue,Thorunn Rafnar,Michelle A.T. Hildebrandt,Anne E. Kiltie,Olivier Cussenot,Klaus Golka,Rajesh Kumar,Jack A. Taylor,Jose I. Mayordomo,Kevin B. Jacobs,Manolis Kogevinas,Amy Hutchinson,Zhaoming Wang,Yi-Ping Fu,Ludmila Prokunina-Olsson,Laurie Burdett,Meredith Yeager,William Wheeler,Adonina Tardón,Consol Serra,Alfredo Carrato,Reina García-Closas,Josep Lloreta,Alison Johnson,Molly Schwenn,Margaret R. Karagas,Alan R. Schned,Gerald L. Andriole,Robert L. Grubb,Amanda Black,Eric J. Jacobs,W. Ryan Diver,Susan M. Gapstur,Stephanie J. Weinstein,Jarmo Virtamo,Victoria K. Cortessis,Manuela Gago-Dominguez,Malcolm C. Pike,Malcolm C. Pike,Mariana C. Stern,Jian-Min Yuan,David J. Hunter,Monica McGrath,Colin P.N. Dinney,Bogdan Czerniak,Meng Chen,Hushan Yang,Sita H. Vermeulen,Katja K.H. Aben,J. Alfred Witjes,Remco R. R. Makkinje,Patrick Sulem,Søren Besenbacher,Kari Stefansson,Kari Stefansson,Elio Riboli,Paul Brennan,Salvatore Panico,Carmen Navarro,Naomi E. Allen,H. Bas Bueno-de-Mesquita,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Neil E. Caporaso,Maria Teresa Landi,Federico Canzian,Börje Ljungberg,Anne Tjønneland,Françoise Clavel-Chapelon,D T Bishop,Mark Teo,Margaret A. Knowles,Simonetta Guarrera,Silvia Polidoro,Fulvio Ricceri,Carlotta Sacerdote,Alessandra Allione,Geraldine Cancel-Tassin,Silvia Selinski,Jan G. Hengstler,Holger Dietrich,Tony Fletcher,Peter Rudnai,Eugen Gurzau,Kvetoslava Koppova,Sophia C.E. Bolick,Ashley C. Godfrey,Zongli Xu,José I Sanz-Velez,Maria D. Garcia-Prats,Manuel Sanchez,Gabriel Valdivia,Stefano Porru,Simone Benhamou,Simone Benhamou,Robert N. Hoover,Joseph F. Fraumeni,Debra T. Silverman,Stephen J. Chanock +113 more
TL;DR: Two new regions associated with bladder cancer on chromosomes 22q13.1, 19q12 and 2q37.1 are identified and previous candidate associations for the GSTM1 deletion and a tag SNP for NAT2 acetylation status are validated, and interactions with smoking in both regions are found.
Journal ArticleDOI
ENmix: a novel background correction method for Illumina HumanMethylation450 BeadChip.
TL;DR: A novel background correction method, ENmix, that uses a mixture of exponential and truncatednormal distributions to flexibly model signal intensity and uses a truncated normal distribution to model background noise is developed.
Journal ArticleDOI
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium
Gemma C Sharp,Gemma C Sharp,Lucas A. Salas,Lucas A. Salas,Claire Monnereau,Claire Monnereau,Catherine Allard,Paul Yousefi,Todd M. Everson,Jon Bohlin,Zongli Xu,Rae-Chi Huang,Sarah E. Reese,Cheng-Jian Xu,Nour Baïz,Cathrine Hoyo,Golareh Agha,Ritu Roy,Ritu Roy,John W. Holloway,Akram Ghantous,Simon Kebede Merid,Kelly M. Bakulski,Leanne K. Küpers,Hongmei Zhang,Rebecca C Richmond,Christian M. Page,Liesbeth Duijts,Liesbeth Duijts,Rolv T. Lie,Phillip E. Melton,Judith M. Vonk,Ellen A. Nohr,ClarLynda R. Williams-DeVane,Karen Huen,Sheryl L. Rifas-Shiman,Carlos Ruiz-Arenas,Semira Gonseth,Semira Gonseth,Faisal I. Rezwan,Zdenko Herceg,Sandra Ekström,Lisa A. Croen,Fahimeh Falahi,Patrice Perron,Margaret R. Karagas,Bilal M. Quraishi,Matthew Suderman,Maria C. Magnus,Maria C. Magnus,Vincent W. V. Jaddoe,Vincent W. V. Jaddoe,Jack A. Taylor,Jack A. Taylor,Denise Anderson,Shanshan Zhao,Henriette A. Smit,Michele J. Josey,Michele J. Josey,Asa Bradman,Andrea A. Baccarelli,Mariona Bustamante,Siri E. Håberg,Göran Pershagen,Göran Pershagen,Irva Hertz-Picciotto,Craig J. Newschaffer,Eva Corpeleijn,Luigi Bouchard,Debbie A Lawlor,Rachel L. Maguire,Lisa F. Barcellos,George Davey Smith,Brenda Eskenazi,Wilfried Karmaus,Carmen J. Marsit,Marie-France Hivert,Marie-France Hivert,Harold Snieder,M. Daniele Fallin,Erik Melén,Erik Melén,Erik Melén,Monica Cheng Munthe-Kaas,Monica Cheng Munthe-Kaas,S. Hasan Arshad,S. Hasan Arshad,Joseph L. Wiemels,Isabella Annesi-Maesano,Martine Vrijheid,Emily Oken,Nina Holland,Susan K. Murphy,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Gerard H. Koppelman,John P. Newnham,Allen J. Wilcox,Wenche Nystad,Stephanie J. London,Janine F. Felix,Janine F. Felix,Caroline L Relton +103 more
TL;DR: In this article, the association between pre-pregnancy maternal BMI and methylation at over 450,000 sites in newborn blood DNA, across 19 cohorts (9,340 mother-newborn pairs).