M
Matthias W. Beckmann
Researcher at University of Erlangen-Nuremberg
Publications - 913
Citations - 40161
Matthias W. Beckmann is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 83, co-authored 836 publications receiving 33443 citations. Previous affiliations of Matthias W. Beckmann include National Institutes of Health & University of Chicago.
Papers
More filters
Journal ArticleDOI
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46 450 cases and 42 461 controls from the breast cancer association consortium
Roger L. Milne,Jesús Herranz,Kyriaki Michailidou,Joe Dennis,Jonathan Tyrer,Pilar Zamora,José Ignacio Arias-Perez,Anna González-Neira,Guillermo Pita,M. Rosario Alonso,Qin Wang,Manjeet K. Bolla,Kamila Czene,Mikael Eriksson,Keith Humphreys,Hatef Darabi,Jingmei Li,Hoda Anton-Culver,Susan L. Neuhausen,Argyrios Ziogas,Christina A. Clarke,John L. Hopper,Gillian S. Dite,Carmel Apicella,Melissa C. Southey,Georgia Chenevix-Trench,kConFab Investigators,Anthony J. Swerdlow,Anthony J. Swerdlow,Alan Ashworth,Alan Ashworth,Nick Orr,Minouk J. Schoemaker,Anna Jakubowska,Jan Lubinski,Katarzyna Jaworska-Bieniek,Katarzyna Durda,Irene L. Andrulis,Julia A. Knight,Julia A. Knight,Gord Glendon,Anna Marie Mulligan,Anna Marie Mulligan,Stig E. Bojesen,Børge G. Nordestgaard,Henrik Flyger,Heli Nevanlinna,Taru A. Muranen,Kristiina Aittomäki,Carl Blomqvist,Jenny Chang-Claude,Anja Rudolph,Petra Seibold,Dieter Flesch-Janys,Xianshu Wang,Janet E. Olson,Celine M. Vachon,Kristen S. Purrington,Robert Winqvist,Katri Pylkäs,Arja Jukkola-Vuorinen,Mervi Grip,Alison M. Dunning,Mitul Shah,Pascal Guénel,Thérèse Truong,Marie Sanchez,Claire Mulot,Hermann Brenner,Aida Karina Dieffenbach,Volker Arndt,Christa Stegmaier,Annika Lindblom,Sara Margolin,Maartje J. Hooning,Antoinette Hollestelle,J. Margriet Collée,Agnes Jager,Angela Cox,Ian W. Brock,Malcolm W.R. Reed,Peter Devilee,Robert A.E.M. Tollenaar,Caroline Seynaeve,Christopher A. Haiman,Brian E. Henderson,Fredrick R. Schumacher,Loic Le Marchand,Jacques Simard,Martine Dumont,Penny Soucy,Thilo Dörk,Natalia Bogdanova,Ute Hamann,Asta Försti,Thomas Rüdiger,Hans Ulrich Ulmer,Peter A. Fasching,Peter A. Fasching,Lothar Häberle,Arif B. Ekici,Matthias W. Beckmann,Olivia Fletcher,Nichola Johnson,Isabel dos Santos Silva,Julian Peto,Paolo Radice,Paolo Peterlongo,Bernard Peissel,Paolo Mariani,Graham G. Giles,Gianluca Severi,Laura Baglietto,Elinor J. Sawyer,Ian Tomlinson,Ian Tomlinson,Michael J. Kerin,Nicola Miller,Federik Marme,Barbara Burwinkel,Arto Mannermaa,Vesa Kataja,Veli-Matti Kosma,Jaana M. Hartikainen,Diether Lambrechts,Betül T. Yesilyurt,Giuseppe Floris,Karin Leunen,Grethe I. Grenaker Alnæs,Vessela N. Kristensen,Anne Lise Børresen-Dale,Montserrat Garcia-Closas,Stephen J. Chanock,Jolanta Lissowska,Jonine D. Figueroa,Marjanka K. Schmidt,Annegien Broeks,Senno Verhoef,Emiel J. Th. Rutgers,Hiltrud Brauch,Hiltrud Brauch,Thomas Brüning,Yon-Dschun Ko,Fergus J. Couch,Amanda E. Toland,Drakoulis Yannoukakos,Paul D.P. Pharoah,Per Hall,Javier Benitez,Núria Malats,Douglas F. Easton +150 more
TL;DR: Little evidence of two-way SNP interactions in breast cancer susceptibility is observed, despite the large number of SNPs with potential marginal effects considered and the very large sample size, which may have important implications for risk prediction.
Journal ArticleDOI
Xenotransplantation of cryopreserved ovarian tissue from patients with ovarian tumors into SCID mice—no evidence of malignant cell contamination
Laura Lotz,Markus Montag,Hans van der Ven,Michael von Wolff,Andreas Mueller,Inge Hoffmann,David L. Wachter,Matthias W. Beckmann,Ralf Dittrich +8 more
TL;DR: This study examined the possible presence of malignant cells in ovarian cortex from patients with ovarian tumors after xenografting of the ovarian tissue into severe combined immunodeficiency mice.
Journal ArticleDOI
Expression of neuroendocrine markers in different molecular subtypes of breast carcinoma
David L. Wachter,Arndt Hartmann,Matthias W. Beckmann,Peter A. Fasching,Alexander Hein,Christian M. Bayer,Abbas Agaimy +6 more
TL;DR: It is concluded that neuroendocrine differentiation is more common than assumed in poorly differentiated luminal B-like carcinomas, and use of specific neuro endocrine markers is encouraged in this subtype to enhance detection of neuroendsocrine differentiation.
Journal ArticleDOI
Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer
Jiajun Shi,Yanfeng Zhang,Wei Zheng,Kyriaki Michailidou,Maya Ghoussaini,Manjeet K. Bolla,Qin Wang,Joe Dennis,Michael Lush,Roger L. Milne,Roger L. Milne,Xiao-Ou Shu,Jonathan Beesley,Siddhartha Kar,Irene L. Andrulis,Irene L. Andrulis,Hoda Anton-Culver,Volker Arndt,Matthias W. Beckmann,Zhiguo Zhao,Xingyi Guo,Javier Benitez,Alicia Beeghly-Fadiel,William J. Blot,Natalia Bogdanova,Stig E. Bojesen,Stig E. Bojesen,Stig E. Bojesen,Hiltrud Brauch,Hiltrud Brauch,Hiltrud Brauch,Hermann Brenner,Louise A. Brinton,Annegien Broeks,Thomas Brüning,Barbara Burwinkel,Hui Cai,Sander Canisius,Jenny Chang-Claude,Ji Yeob Choi,Fergus J. Couch,Angela Cox,Simon S. Cross,Kamila Czene,Hatef Darabi,Peter Devilee,Arnaud Droit,Thilo Dörk,Peter A. Fasching,Peter A. Fasching,Olivia Fletcher,Henrik Flyger,Florentia Fostira,Valerie Gaborieau,Montserrat Garcia-Closas,Montserrat Garcia-Closas,Graham G. Giles,Graham G. Giles,Mervi Grip,Pascal Guénel,Christopher A. Haiman,Ute Hamann,Mikael Hartman,Mikael Hartman,Hui Miao,Antoinette Hollestelle,John L. Hopper,Chia-Ni Hsiung,kConFab Investigators,Hidemi Ito,Anna Jakubowska,Nichola Johnson,Diana Torres,Diana Torres,Maria Kabisch,Daehee Kang,Sofia Khan,Julia A. Knight,Julia A. Knight,Veli-Matti Kosma,Diether Lambrechts,Jingmei Li,Annika Lindblom,Artitaya Lophatananon,Jan Lubinski,Arto Mannermaa,Siranoush Manoukian,Loic Le Marchand,Sara Margolin,Frederik Marmé,Keitaro Matsuo,Catriona McLean,Alfons Meindl,Kenneth Muir,Kenneth Muir,Susan L. Neuhausen,Heli Nevanlinna,Silje Nord,Silje Nord,Anne Lise Børresen-Dale,Anne Lise Børresen-Dale,Janet E. Olson,Nick Orr,Ans M.W. van den Ouweland,Paolo Peterlongo,Thomas C. Putti,Anja Rudolph,Suleeporn Sangrajrang,Elinor J. Sawyer,Marjanka K. Schmidt,Rita K. Schmutzler,Chen-Yang Shen,Chen-Yang Shen,Ming-Feng Hou,Matha J. Shrubsole,Melissa C. Southey,Anthony J. Swerdlow,Soo-Hwang Teo,Bernard Thienpont,Amanda E. Toland,Robert A.E.M. Tollenaar,Ian Tomlinson,Thérèse Truong,Chiu-Chen Tseng,Wanqing Wen,Robert Winqvist,Anna H. Wu,Cheng Har Yip,Pilar Zamora,Ying Zheng,Giuseppe Floris,Ching-Yu Cheng,Maartje J. Hooning,John W.M. Martens,Caroline Seynaeve,Vessela N. Kristensen,Per Hall,Paul D.P. Pharoah,Jacques Simard,Georgia Chenevix-Trench,Georgia Chenevix-Trench,Alison M. Dunning,Antonis C. Antoniou,Douglas F. Easton,Qiuyin Cai,Jirong Long +145 more
TL;DR: The results highlighted multiple 8q24 variants associated with breast cancer susceptibility in women of European ancestry and suggested SNPs rs7815245 in Signal 3, and rs1121948 in Signal 5, were putatively functional variants for two of the five independent association signals.
Shared genetics underlying epidemiological association between endometriosis and ovarian cancer
Yi Lu,Gabriel Cuellar-Partida,Jodie N. Painter,Dale R. Nyholt,Andrew P. Morris,Peter A. Fasching,Alexander Hein,S Burghaus,Matthias W. Beckmann,Diether Lambrechts,E Van Nieuwenhuysen,Ignace Vergote,Adriaan Vanderstichele,Jennifer A. Doherty,Rossing,Kristine G. Wicklund,Jenny Chang-Claude,Ursula Eilber,Anja Rudolph,Shan Wang-Gohrke,Marc T. Goodman,Natalia Bogdanova,Thilo Dörk,Matthias Dürst,Peter Hillemanns,Ingo B. Runnebaum,Natalia Antonenkova,Ralf Bützow,Arto Leminen,Heli Nevanlinna,Liisa M. Pelttari,Robert P. Edwards,Joseph L. Kelley,Francesmary Modugno,Kirsten B. Moysich,Roberta B. Ness,Rikki Cannioto,Estrid Høgdall,Allan Jensen,Graham G. Giles,Fiona Bruinsma,Susanne K. Kjaer,Michelle A.T. Hildebrandt,Dong Liang,Karen Lu,Xifeng Wu,Maria Bisogna,Fanny Dao,Douglas A. Levine,Daniel W. Cramer,Kathryn L. Terry,Shelley S. Tworoger,Stacey A. Missmer,Line Bjørge,Helga B. Salvesen,Reidun K. Kopperud,Katharina Bischof,Katja K.H. Aben,Lambertus A. Kiemeney,L.F.A.G. Massuger,Angela Brooks-Wilson,Sara H. Olson,Valerie McGuire,Joseph H. Rothstein,Weiva Sieh,Alice S. Whittemore,Linda S. Cook,Nhu D. Le,C. BlakeGilks,Jacek Gronwald,Anna Jakubowska,Jan Lubinski,Jan Gawełko,Honglin Song,Jonathan Tyrer,Nicolas Wentzensen,Louise A. Brinton,Britton Trabert,Jolanta Lissowska,John R. McLaughlin,Steven A. Narod,Catherine M. Phelan,Hoda Anton-Culver,Argyrios Ziogas,Diana Eccles,Simon A. Gayther,Aleksandra Gentry-Maharaj,Usha Menon,Susan J. Ramus,Anna H. Wu,Agnieszka Dansonka-Mieszkowska,Jolanta Kupryjanczyk,Agnieszka Timorek,Lukasz Szafron,Julie M. Cunningham,Brooke L. Fridley,Stacey J. Winham,Elisa V. Bandera,Elizabeth M. Poole,Terry K. Morgan,Harvey A. Risch,Ellen L. Goode,Joellen M. Schildkraut,Penelope M. Webb,Celeste Leigh Pearce,Andrew Berchuck,Paul D.P. Pharoah,Grant W. Montgomery,Krina T. Zondervan,Georgia Chenevix-Trench,Stuart MacGregor +110 more
TL;DR: In this article, the authors found evidence for shared genetic risks between endometriosis and all histotypes of ovarian cancer, except for the intestinal mucinous type, using the customized Illumina Infinium iSelect (iCOGS) arrays.