M
Michael B. Sporn
Researcher at Dartmouth College
Publications - 561
Citations - 96644
Michael B. Sporn is an academic researcher from Dartmouth College. The author has contributed to research in topics: Transforming growth factor & Transforming growth factor beta. The author has an hindex of 157, co-authored 559 publications receiving 94605 citations. Previous affiliations of Michael B. Sporn include Cornell University & Reata Pharmaceuticals.
Papers
More filters
Journal ArticleDOI
Can dietary beta-carotene materially reduce human cancer rates?
TL;DR: If dietary β-carotene is truly protective—which could be tested by controlled trials—there are a number of theoretical mechanisms whereby it might act, some of which do not directly involve its ‘provitamin A’ activity.
Journal ArticleDOI
Autocrine growth factors and cancer.
TL;DR: The ability of cancer cells to produce and to respond to their own growth factors (autocrine secretion) has become a central concept linking oncogene and growth factor research.
Journal ArticleDOI
Autocrine Secretion and Malignant Transformation of Cells
TL;DR: The growth of normal cells is largely controlled by the interplay between several polypeptide hormones and hormone-like growth factors that are present in tissue fluids.
Book
The Retinoids : biology, chemistry, and medicine
TL;DR: Retinoids In Photosensitive Systems John C. Saari Introduction / Overview of the Visual Process / Chromophores of Visual Pigments /photoisomerisation / Wavelength Regulation The Visual Cycle /Cellular Uptake of Retinol.
Journal ArticleDOI
Some recent advances in the chemistry and biology of transforming growth factor-beta.
TL;DR: It is clear that there is no one principal action for TGF-beta; moreover, the almost universal cellular distribution of its receptor encompasses a very broad spectrum of target tissues.