M
Myvizhi Esai Selvan
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 23
Citations - 1949
Myvizhi Esai Selvan is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 8, co-authored 20 publications receiving 1187 citations. Previous affiliations of Myvizhi Esai Selvan include Schrödinger.
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Journal ArticleDOI
Immunology of COVID-19: Current State of the Science.
Nicolas Vabret,Graham J. Britton,Conor Gruber,Samarth Hegde,Joel Kim,Maria Kuksin,Rachel Levantovsky,Louise Malle,Alvaro Moreira,Matthew D. Park,Luisanna Pia,Emma Risson,Miriam Saffern,Bérengère Salomé,Myvizhi Esai Selvan,Matthew P. Spindler,Jessica Tan,Verena van der Heide,Jill Gregory,Konstantina Alexandropoulos,Nina Bhardwaj,Brian D. Brown,Benjamin Greenbaum,Zeynep H. Gümüş,Dirk Homann,Amir Horowitz,Alice O. Kamphorst,Maria A. Curotto de Lafaille,Saurabh Mehandru,Miriam Merad,Robert M. Samstein,Manasi Agrawal,Mark Aleynick,Meriem Belabed,Matthew Brown,Maria Casanova-Acebes,Jovani Catalan,Monica Centa,Andrew Charap,Andrew K Chan,Steven T. Chen,Jonathan Chung,Cansu Cimen Bozkus,Evan Cody,Francesca Cossarini,Erica Dalla,Nicolas F. Fernandez,John A. Grout,Dan Fu Ruan,Pauline Hamon,Etienne Humblin,Divya Jha,Julia Kodysh,Andrew Leader,Matthew Lin,Katherine E. Lindblad,Daniel Lozano-Ojalvo,Gabrielle Lubitz,Assaf Magen,Zafar Mahmood,Gustavo Martinez-Delgado,Jaime Mateus-Tique,Elliot Meritt,Chang Moon,Justine Noel,Timothy O'Donnell,Miyo Ota,Tamar Plitt,Venu Pothula,Jamie Redes,Ivan Reyes Torres,Mark P. Roberto,Alfonso R. Sanchez-Paulete,Joan Shang,Alessandra Soares Schanoski,Maria Suprun,Michelle Tran,Natalie Vaninov,C. Matthias Wilk,Julio A. Aguirre-Ghiso,Dusan Bogunovic,Judy H. Cho,Jeremiah J. Faith,Emilie K. Grasset,Peter S. Heeger,Ephraim Kenigsberg,Florian Krammer,Uri Laserson +87 more
TL;DR: The current state of knowledge of innate and adaptive immune responses elicited by SARS-CoV-2 infection and the immunological pathways that likely contribute to disease severity and death are summarized.
Journal ArticleDOI
Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma
Michael A. Gillette,Michael A. Gillette,Shankha Satpathy,Song Cao,Saravana M. Dhanasekaran,Suhas Vasaikar,Karsten Krug,Francesca Petralia,Yize Li,Wen-Wei Liang,Boris Reva,Azra Krek,Jiayi Ji,Xiaoyu Song,Wenke Liu,Runyu Hong,Lijun Yao,Lili Blumenberg,Sara R. Savage,Michael C. Wendl,Bo Wen,Kai Li,Lauren C. Tang,Lauren C. Tang,Melanie A. MacMullan,Melanie A. MacMullan,Shayan C. Avanessian,M. Harry Kane,Chelsea J. Newton,MacIntosh Cornwell,Ramani B. Kothadia,Weiping Ma,Seungyeul Yoo,Rahul Mannan,Pankaj Vats,Chandan Kumar-Sinha,Emily Kawaler,Tatiana Omelchenko,Antonio Colaprico,Yifat Geffen,Yosef E. Maruvka,Felipe da Veiga Leprevost,Maciej Wiznerowicz,Maciej Wiznerowicz,Zeynep H. Gümüş,Rajwanth R. Veluswamy,Galen Hostetter,David I. Heiman,Matthew A. Wyczalkowski,Tara Hiltke,Mehdi Mesri,Christopher R. Kinsinger,Emily S. Boja,Gilbert S. Omenn,Arul M. Chinnaiyan,Henry Rodriguez,Qing Kay Li,Scott D. Jewell,Mathangi Thiagarajan,Gad Getz,Bing Zhang,David Fenyö,Kelly V. Ruggles,Marcin Cieslik,Ana I. Robles,Karl R. Clauser,Ramaswamy Govindan,Pei Wang,Alexey I. Nesvizhskii,Li Ding,D. R. Mani,Steven A. Carr,Alex Webster,Alicia Francis,Alyssa Charamut,Amanda G. Paulovich,Amy M. Perou,Andrew K. Godwin,Andrii Karnuta,Annette Marrero-Oliveras,Barbara Hindenach,Barbara Pruetz,Bartosz Kubisa,Brian J. Druker,Chet Birger,Corbin D. Jones,Dana R. Valley,Daniel C. Rohrer,Daniel Cui Zhou,Daniel W. Chan,David Chesla,David J. Clark,Dmitry Rykunov,Donghui Tan,Elena V. Ponomareva,Elizabeth R. Duffy,Eric J. Burks,Eric E. Schadt,Erik J. Bergstrom,Eugene S. Fedorov,Ewa P. Malc,George D. Wilson,Hai-Quan Chen,Halina M. Krzystek,Hongwei Liu,Houston Culpepper,Hua Sun,Hui Zhang,Jacob J. Day,James Suh,Jeffrey R. Whiteaker,Jennifer M. Eschbacher,John McGee,Karen A. Ketchum,Karin D. Rodland,Karna Robinson,Katherine A. Hoadley,Kei Suzuki,Ki Sung Um,Kim Elburn,Liang-Bo Wang,Lijun Chen,Linda Hannick,Liqun Qi,Lori J. Sokoll,Małgorzata Wojtyś,Marcin J. Domagalski,Marina A. Gritsenko,Mary Beth Beasley,Matthew E. Monroe,Matthew J. Ellis,Maureen Dyer,Meghan C. Burke,Melissa Borucki,Meng-Hong Sun,Michael H.A. Roehrl,Michael J. Birrer,Michael S. Noble,Michael Schnaubelt,Michael Vernon,Michelle Chaikin,Mikhail Krotevich,Munziba Khan,Myvizhi Esai Selvan,Nancy Roche,Nathan Edwards,Negin Vatanian,Olga Potapova,Pamela Grady,Peter B. McGarvey,Piotr A. Mieczkowski,Pushpa Hariharan,Rashna Madan,Ratna R. Thangudu,Richard D. Smith,Robert J. Welsh,Robert Zelt,Rohit Mehra,Ronald Matteotti,Sailaja Mareedu,Samuel H. Payne,Sandra Cottingham,Sanford P. Markey,Seema Chugh,Shaleigh Smith,Shirley Tsang,Shuang Cai,Simina M. Boca,Sonya Carter,Stacey Gabriel,Stephanie De Young,Stephen E. Stein,Sunita Shankar,Tanya Krubit,Tao Liu,Tara Skelly,Thomas L. Bauer,Uma Velvulou,Umut Ozbek,Vladislav A. Petyuk,Volodymyr Sovenko,William Bocik,William W. Maggio,Xi Chen,Yan Shi,Yige Wu,Yingwei Hu,Yuxing Liao,Zhen Zhang,Zhiao Shi +189 more
TL;DR: Comprehensive proteogenomic characterization of 110 tumors and 101 matched normal adjacent tissues (NATs) incorporating genomics, epigenomics, deep-scale proteomics, phosphoproteomics, and acetylproteomics identified therapeutic vulnerabilities associated with driver events involving KRAS, EGFR, and ALK.
Journal ArticleDOI
A proteogenomic portrait of lung squamous cell carcinoma
Shankha Satpathy,Karsten Krug,Pierre M. Jean Beltran,Sara R. Savage,Francesca Petralia,Chandan Kumar-Sinha,Yongchao Dou,Boris Reva,M. Harry Kane,Shayan C. Avanessian,Suhas Vasaikar,Azra Krek,Jonathan T. Lei,Eric J. Jaehnig,Tatiana Omelchenko,Yifat Geffen,Erik J. Bergstrom,Vasileios Stathias,Karen E. Christianson,David I. Heiman,Marcin Cieslik,Song Cao,Xiaoyu Song,Jiayi Ji,Wenke Liu,Kai Li,Bo Wen,Yize Li,Zeynep H. Gümüş,Myvizhi Esai Selvan,Rama Soundararajan,Tanvi H. Visal,Maria Gabriela Raso,Edwin R. Parra,Özgün Babur,Pankaj Vats,Shankara Anand,Tobias Schraink,MacIntosh Cornwell,Fernanda Martins Rodrigues,Houxiang Zhu,Chia-Kuei Mo,Yuping Zhang,Felipe da Veiga Leprevost,Chen Huang,Arul M. Chinnaiyan,Matthew A. Wyczalkowski,Gilbert S. Omenn,Chelsea J. Newton,Stephan C. Schürer,Kelly V. Ruggles,David Fenyö,Scott D. Jewell,Mathangi Thiagarajan,Mehdi Mesri,Henry Rodriguez,Sendurai A. Mani,Namrata D. Udeshi,Gad Getz,James Suh,Qing Kay Li,Galen Hostetter,Paul K. Paik,Saravana M. Dhanasekaran,Ramaswamy Govindan,Li Ding,Ana I. Robles,Karl R. Clauser,Alexey I. Nesvizhskii,Pei Wang,Steven A. Carr,Bing Zhang,D. R. Mani,Michael A. Gillette,Michael A. Gillette,Alexander A. Green,Alfredo Molinolo,Alicia Francis,Amanda G. Paulovich,Andrii Karnuta,Antonio Colaprico,Barbara Hindenach,Barbara Pruetz,Bartosz Kubisa,Brian J. Druker,Carissa Huynh,Charles A. Goldthwaite,Chet Birger,Christopher R. Kinsinger,Corbin D. Jones,Daniel C. Rohrer,Dana R. Valley,Daniel W. Chan,David Chesla,Donna E. Hansel,Elena V. Ponomareva,Elizabeth R. Duffy,Eric J. Burks,Eric E. Schadt,Eugene S. Fedorov,Eunkyung An,Fei Ding,George D. Wilson,Harsh Batra,Hui Zhang,Jennifer E. Maas,Jennifer M. Eschbacher,Karen A. Ketchum,Karin D. Rodland,Katherine A. Hoadley,Kei Suzuki,Ki Sung Um,Liqun Qi,Lori Bernard,Maciej Wiznerowicz,Małgorzata Wojtyś,Marcin J. Domagalski,Matthew J. Ellis,Maureen Dyer,Melissa Borucki,Meenakshi Anurag,Michael J. Birrer,Midie Xu,Mikhail Krotevich,Nancy Roche,Nathan Edwards,Negin Vatanian,Neil R. Mucci,Nicollette Maunganidze,Nikolay Gabrovski,Olga Potapova,Oluwole Fadare,Pamela Grady,Peter B. McGarvey,Pushpa Hariharan,Ratna R. Thangudu,Rebecca I. Montgomery,Renganayaki Pandurengan,Richard D. Smith,Robert J. Welsh,Sailaja Mareedu,Samuel H. Payne,Sandra Cottingham,Shilpi Singh,Shirley Tsang,Shuang Cai,Stacey Gabriel,Tao Liu,Tara Hiltke,Tanmayi Vashist,Thomas L. Bauer,Volodymyr Sovenko,Warren G. Tourtellotte,Weiping Ma,William Bocik,Wohaib Hasan,Xiaojun Jing,Ximing Tang,Yuxing Liao,Yvonne,Shutack,Zhen Zhang,Ziad Hanhan +162 more
TL;DR: In this article, the authors characterized the proteogenomic landscape of LSCC and provided a deeper exposition of the LSCC biology with potential therapeutic implications, identifying NSD3 as an alternative driver in FGFR1-amplified tumors and low-p63 tumors overexpressing the therapeutic target survivin.
Journal ArticleDOI
Risk factors for death from COVID-19.
TL;DR: This study provides evidence for a direct pathway through which brain activity can tune immune system functioning, adding to the growing understanding of brain–body interconnectivity.
Journal ArticleDOI
Identification of SERPINE1 as a Regulator of Glioblastoma Cell Dispersal with Transcriptome Profiling
Fidan Seker,Ahmet Cingoz,Ilknur Sur-Erdem,Nazli Erguder,Alp Erkent,Fırat Uyulur,Myvizhi Esai Selvan,Zeynep H. Gümüş,Mehmet Gönen,Halil Bayraktar,Hiroaki Wakimoto,Tugba Bagci-Onder +11 more
TL;DR: In this paper, the authors analyzed transcriptome of motile (dispersive) and non-motile (core) GBM cells using an in vitro spheroid dispersal model and identified SERPINE1 as a modulator of GBM cell dispersal.