S
Stephane C. Lefebvre
Researcher at J. Craig Venter Institute
Publications - 14
Citations - 1665
Stephane C. Lefebvre is an academic researcher from J. Craig Venter Institute. The author has contributed to research in topics: Emiliania huxleyi & Photosynthesis. The author has an hindex of 13, co-authored 14 publications receiving 1430 citations. Previous affiliations of Stephane C. Lefebvre include San Francisco State University & University of Essex.
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Journal ArticleDOI
Pan genome of the phytoplankton Emiliania underpins its global distribution
Betsy A. Read,Jessica Kegel,Mary J. Klute,Alan Kuo,Stephane C. Lefebvre,Florian Maumus,Christoph Mayer,John P. Miller,Adam Monier,Asaf Salamov,Jeremy R. Young,María Aguilar,Jean-Michel Claverie,Stephan Frickenhaus,Karina Gonzalez,Emily K. Herman,Yao-Cheng Lin,Johnathan A. Napier,Hiroyuki Ogata,Analissa F. Sarno,Jeremy Shmutz,Declan C. Schroeder,Colomban de Vargas,Frédéric Verret,Peter von Dassow,Klaus Valentin,Yves Van de Peer,Glen L. Wheeler,Joel B. Dacks,Charles F. Delwiche,Sonya T. Dyhrman,Sonya T. Dyhrman,Sonya T. Dyhrman,Gernot Glöckner,Uwe John,Thomas A. Richards,Alexandra Z. Worden,Xiaoyu Zhang,Igor V. Grigoriev,Andrew E. Allen,Kay D. Bidle,Kay D. Bidle,Mark Borodovsky,Chris Bowler,Colin Brownlee,Colin Brownlee,J. Mark Cock,Marek Eliáš,Vadim N. Gladyshev,Marco Groth,Chittibabu Guda,Ahmad R. Hadaegh,M. D. Iglesias-Rodriguez,Jerry Jenkins,Bethan M. Jones,Tracy Lawson,Florian Leese,Erika Lindquist,Alexei Lobanov,Alexandre Lomsadze,Shehre-Banoo Malik,Mary E. Marsh,Luke C. M. Mackinder,Thomas Mock,Bernd Mueller-Roeber,António Pagarete,Micaela S. Parker,Ian Probert,Hadi Quesneville,Christine A. Raines,Stefan A. Rensing,Stefan A. Rensing,Diego Mauricio Riaño-Pachón,Sophie Richier,Sophie Richier,Sebastian D. Rokitta,Yoshihiro Shiraiwa,Darren M. Soanes,Mark van der Giezen,Thomas M. Wahlund,Bryony A. P. Williams,Willie Wilson,Gordon Wolfe,Louie L. Wurch,Louie L. Wurch +84 more
TL;DR: Comparisons across strains demonstrate that E. huxleyi, which has long been considered a single species, harbours extensive genome variability reflected in different metabolic repertoires, and reveals a pan genome (core genes plus genes distributed variably between strains) probably supported by an atypical complement of repetitive sequence in the genome.
Journal ArticleDOI
Increased Sedoheptulose-1,7-Bisphosphatase Activity in Transgenic Tobacco Plants Stimulates Photosynthesis and Growth from an Early Stage in Development
TL;DR: It is shown that photosynthetic capacity per unit area and plant yield can be increased by overexpressing a single native plant enzyme, SBPase, and that this gives an advantage to the growth of these plants from an early phase of vegetative growth.
Journal ArticleDOI
Designer diatom episomes delivered by bacterial conjugation
Bogumil J. Karas,Rachel E. Diner,Rachel E. Diner,Stephane C. Lefebvre,Jeffrey B. McQuaid,Alex P.R. Phillips,Chari Noddings,John K. Brunson,Ruben E. Valas,Thomas J. Deerinck,Jelena Jablanovic,Jeroen Gillard,Karen Beeri,Mark H. Ellisman,John I. Glass,Clyde A. Hutchison,Hamilton O. Smith,J. Craig Venter,Andrew E. Allen,Andrew E. Allen,Christopher L. Dupont,Philip D. Weyman +21 more
TL;DR: A yeast-derived sequence is identified that enables stable episome replication in these diatoms even in the absence of antibiotic selection and it is shown that episomes are maintained as closed circles at copy number equivalent to native chromosomes.
Journal ArticleDOI
Inactivation of Phaeodactylum tricornutum urease gene using transcription activator-like effector nuclease-based targeted mutagenesis.
Philip D. Weyman,Karen Beeri,Stephane C. Lefebvre,Josefa Rivera,James K. McCarthy,Adam L. Heuberger,Graham Peers,Andrew E. Allen,Andrew E. Allen,Christopher L. Dupont +9 more
TL;DR: Improved the molecular toolkit for diatoms and clarifies the role of urease in the urea cycle is clarified, suggesting a disruption of the cycle despite urea production.
Journal ArticleDOI
The trade-off between the light-harvesting and photoprotective functions of fucoxanthin-chlorophyll proteins dominates light acclimation in Emiliania huxleyi (clone CCMP 1516).
Boyd A. McKew,Phillip A. Davey,Stewart J. Finch,Jason Hopkins,Stephane C. Lefebvre,Metodi V. Metodiev,Kevin Oxborough,Christine A. Raines,Tracy Lawson,Richard J. Geider +9 more
TL;DR: In this article, the authors tested the hypothesis that changes in the light dependencies of photosynthesis, nonphotochemical quenching and PSII photoinactivation arises from changes in chloroplast proteins in CCMP 1516 grown at 30 (Low Light; LL) and 1000 (High Light; HL) μmol photons m(-2) s(-1) photon flux densities.