T
Tanya L. Leise
Researcher at Amherst College
Publications - 63
Citations - 2115
Tanya L. Leise is an academic researcher from Amherst College. The author has contributed to research in topics: Circadian rhythm & Suprachiasmatic nucleus. The author has an hindex of 22, co-authored 53 publications receiving 1753 citations.
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Journal ArticleDOI
The $25,000,000,000 Eigenvector: The Linear Algebra behind Google
Kurt Bryan,Tanya L. Leise +1 more
TL;DR: Analysis of the PageRank formula provides a wonderful applied topic for a linear algebra course and complements the discussion of Markov chains in matrix algebra.
Journal ArticleDOI
Guidelines for Genome-Scale Analysis of Biological Rhythms
Michael E. Hughes,Katherine C. Abruzzi,Ravi Allada,Ron C. Anafi,Alaaddin Bulak Arpat,Alaaddin Bulak Arpat,Gad Asher,Pierre Baldi,Charissa de Bekker,Deborah Bell-Pedersen,Justin Blau,Steve Brown,M. Fernanda Ceriani,Zheng Chen,Joanna C. Chiu,Juergen Cox,Alexander M. Crowell,Jason P. DeBruyne,Derk-Jan Dijk,Luciano DiTacchio,Francis J. Doyle,Giles E. Duffield,Jay C. Dunlap,Kristin Eckel-Mahan,Karyn A. Esser,Garret A. FitzGerald,Daniel B. Forger,Lauren J. Francey,Ying-Hui Fu,Frédéric Gachon,David Gatfield,Paul de Goede,Susan S. Golden,Carla B. Green,John Harer,Stacey L. Harmer,Jeff Haspel,Michael H. Hastings,Hanspeter Herzel,Erik D. Herzog,Christy Hoffmann,Christian I. Hong,Jacob J. Hughey,Jennifer M. Hurley,Horacio O. de la Iglesia,Carl Hirschie Johnson,Steve A. Kay,Nobuya Koike,Karl Kornacker,Achim Kramer,Katja A. Lamia,Tanya L. Leise,Scott A. Lewis,Jiajia Li,Jiajia Li,Xiaodong Li,Andrew C. Liu,Jennifer J. Loros,Tami A. Martino,Jerome S. Menet,Martha Merrow,Andrew J. Millar,Todd C. Mockler,Felix Naef,Emi Nagoshi,Michael N. Nitabach,María Teresa Camacho Olmedo,Dmitri A. Nusinow,Louis J. Ptáček,David A. Rand,Akhilesh B. Reddy,Akhilesh B. Reddy,Maria S. Robles,Till Roenneberg,Michael Rosbash,Marc D. Ruben,Samuel S. C. Rund,Aziz Sancar,Paolo Sassone-Corsi,Amita Sehgal,Scott Sherrill-Mix,Debra J. Skene,Kai-Florian Storch,Joseph S. Takahashi,Hiroki R. Ueda,Han Wang,Charles J. Weitz,Pål O. Westermark,Herman Wijnen,Ying Xu,Gang Wu,Seung Hee Yoo,Michael W. Young,Eric E. Zhang,Tomasz Zielinski,John B. Hogenesch +95 more
TL;DR: CircaInSilico is introduced, a web-based application for generating synthetic genome biology data to benchmark statistical methods for studying biological rhythms, and several unmet analytical needs, including applications to clinical medicine, are discussed and productive avenues to address them are suggested.
Journal ArticleDOI
Dynamic interactions mediated by nonredundant signaling mechanisms couple circadian clock neurons.
TL;DR: A functional coupling assay is developed that uniquely captures the dynamic process by which SCN neurons interact and promotes synchrony under steady-state conditions by counteracting the actions of GABAA signaling.
Journal ArticleDOI
Visualizing jet lag in the mouse suprachiasmatic nucleus and peripheral circadian timing system.
Alec J. Davidson,Oscar Castanon-Cervantes,Tanya L. Leise,Penny C. Molyneux,Mary E. Harrington +4 more
TL;DR: There were significant differences in shifting kinetics among mice, among organs such as the spleen and lung, and importantly among neurons in the SCN, the master pacemaker in the brain, as measured by a circadian reporter gene.
Journal ArticleDOI
Aging Differentially Affects the Re-entrainment Response of Central and Peripheral Circadian Oscillators
Michael T. Sellix,Jennifer A. Evans,Tanya L. Leise,Oscar Castanon-Cervantes,DiJon Hill,Patrick Delisser,Gene D. Block,Michael Menaker,Alec J. Davidson +8 more
TL;DR: A pattern of results suggests that a major consequence of aging is a decrease in pacemaker amplitude, which would slow re-entrainment of peripheral oscillators and reduce SCN resistance to external perturbation.