V
Victoria Murday
Researcher at Royal Hospital for Sick Children
Publications - 26
Citations - 2963
Victoria Murday is an academic researcher from Royal Hospital for Sick Children. The author has contributed to research in topics: SDHD & Lynch syndrome. The author has an hindex of 16, co-authored 26 publications receiving 2637 citations.
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Journal ArticleDOI
Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial
John Burn,Anne-Marie Gerdes,Finlay A. Macrae,Jukka-Pekka Mecklin,Gabriela Moeslein,Sylviane Olschwang,D. Eccles,D. Gareth Evans,Eamonn R. Maher,Lucio Bertario,Marie Luise Bisgaard,Malcolm G. Dunlop,Judy W. C. Ho,Shirley V. Hodgson,Annika Lindblom,Jan Lubinski,Patrick J. Morrison,Victoria Murday,Raj Ramesar,Lucy Side,Rodney J. Scott,Huw Thomas,Hans F. A. Vasen,Gail Barker,Gillian Crawford,Faye Elliott,Mohammad Movahedi,Kirsi Pylvänäinen,Juul T. Wijnen,Riccardo Fodde,Henry T. Lynch,John C. Mathers,D. Timothy Bishop +32 more
TL;DR: The CAPP2 trial aimed to investigate the antineoplastic effects of aspirin and a resistant starch in carriers of Lynch syndrome, the major form of hereditary colorectal cancer, and long-term follow-up of participants randomly assigned to aspirin or placebo is reported.
Journal ArticleDOI
Clinical presentation and penetrance of Pheochromocytoma/ Paraganglioma syndromes.
Diana E. Benn,Anne Paule Gimenez-Roqueplo,Jennifer R. Reilly,Jérôme Bertherat,John Burgess,Karen Byth,Michael S. Croxson,Patricia L. M. Dahia,Marianne S. Elston,Oliver Gimm,David Henley,Philippe Herman,Victoria Murday,Patricia Niccoli-Sire,Janice L. Pasieka,Vincent Rohmer,Katherine M. Tucker,Xavier Jeunemaitre,Deborah J. Marsh,Pierre-François Plouin,Bruce G. Robinson,Bruce G. Robinson +21 more
TL;DR: SDHB mutation carriers were more likely than SDHD mutation carriers to develop extraadrenal pheochromocytomas and malignant disease, whereas SD HD mutation carriers had a greater propensity to develop head and neck paragangliomas and multiple tumors.
Journal ArticleDOI
Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
Pia Ostergaard,Michael A. Simpson,Fiona Connell,Colin G. Steward,Glen Brice,Wesley J. Woollard,Dimitra Dafou,Tatjana Kilo,Sarah F. Smithson,Peter Lunt,Victoria Murday,Shirley Hodgson,Russell Keenan,Daniela T. Pilz,Ines Martinez-Corral,Taija Makinen,Peter S. Mortimer,Steve Jeffery,Richard C. Trembath,Sahar Mansour +19 more
TL;DR: It is indicated that haploinsufficiency of GATA2 underlies primary lymphedema and predisposes to acute myeloid leukemia in Emberger syndrome.
Journal ArticleDOI
Mutation update for the CSB/ERCC6 and CSA/ERCC8 genes involved in Cockayne syndrome.
Vincent Laugel,Cecile Dalloz,M. Durand,F. Sauvanaud,U. Kristensen,Marie-Claire Vincent,Laurent Pasquier,Sylvie Odent,Valérie Cormier-Daire,Blanca Gener,Edward S. Tobias,John Tolmie,Dominique Martin-Coignard,Valérie Drouin-Garraud,Delphine Héron,Hubert Journel,E. Raffo,Jacqueline Vigneron,Stanislas Lyonnet,Victoria Murday,D. Gubser-Mercati,Benoît Funalot,Louise Brueton,J. Sanchez del Pozo,E. Muñoz,Andrew R. Gennery,Mustafa A. Salih,Mehrdad Noruzinia,K. Prescott,Lina M. Ramos,Zornitza Stark,Karen Fieggen,Brigitte Chabrol,Pierre Sarda,Patrick Edery,Agnès Bloch-Zupan,Heather Fawcett,D. Pham,Jean-Marc Egly,Alan R. Lehmann,Alain Sarasin,Hélène Dollfus +41 more
TL;DR: This work reviews the 45 published mutations in CSA and CSB to date and reports 43 new mutations in these genes together with the corresponding clinical data, and considersotype–phenotype correlation hypotheses.
Journal ArticleDOI
Mutations in FAM20C Are Associated with Lethal Osteosclerotic Bone Dysplasia (Raine Syndrome), Highlighting a Crucial Molecule in Bone Development
Michael A. Simpson,Ray C. J. Hsu,L. S. Keir,J. Hao,G. Sivapalan,Linda M. Ernst,Linda M. Ernst,Elaine H. Zackai,Lihadh Al-Gazali,G. Hulskamp,Helen Kingston,Trine Prescott,A. Ion,Michael A. Patton,Victoria Murday,Anne George,Andrew H. Crosby +16 more
TL;DR: This study defines the causative role of FAM20C in this lethal osteosclerotic disorder and its crucial role in normal bone development and identifies a chromosome 7 uniparental isodisomy and a 7p telomeric microdeletion in an affected subject.