Bareilly College

About: Bareilly College is a based out in . It is known for research contribution in the topics: Quantitative structure–activity relationship & Population. The organization has 171 authors who have published 214 publications receiving 2127 citations.

Modeling of novel HIV-1 protease inhibitors incorporating N-Aryl-oxazolidinone-5-carboxamides as P2 ligands using quantum chemical and topological finger print descriptors

Abstract: This article presents two QSAR studies on the novel series of HIV-1 protease inhibitors incorporating N-phenyloxazolidinone-5-carboxamides into the (hydroxyethylamino) sulfonamide scaffold as P2 ligands. All the statistical calculations have been done using PRECLAV software. A heuristic algorithm selects the best multiple linear regression (MLR) equation according to the highest leave-one-out cross-validation correlation coefficient. In the first QSAR study, only the Quantum Chemical descriptors have been used. The correlation between the observed values and the calculated values of activity is good (r 2 = 0.935, Se = 0.3782, r 2cv = 0.900, F = 76.6568). The second QSAR study has used both quantum chemical descriptors and topological finger print descriptors. The correlation between the observed values and the calculated values of activity is very good (r 2 = 0.9638, Se = 0.2823, r 2cv = 0.9492, F = 141.8338). The virtual molecular fragments that lead to a significant increase of the inhibitor activity are CH3 and CH. The virtual fragments C4H3S and C6H2 lead to significant decreases in the inhibitory activity. The results are critically discussed using Ridge statistics.

Energy dependence of pre-equilibrium emission for the (p,xn) reactions in niobium

Abstract: Proton induced reactions have been studied in the energy region from ≈7.0 to 12.5 MeV for niobium, using the stacked foil activation technique followed by gamma ray spectroscopy. The excitation functions for the production of 93mMo, 93mNb and 89gZr have been determined. The experimental data have been compared with theoretical calculations based on compound reactions in statistical equilibrium as well as on pre-equilibrium reactions.

Ethnobotany of tharus of dudhwa national park, india

Abstract: Tharus are inhabited on southern foothills of the Himalayas along Indo-Nepal border. They have been using many plant species to meet their day-to-day needs. The aim of this study was to collect information on the traditional uses of different plants and to document the potential economic use of these plants. Fieldwork was conducted over a period of two years in Dudhwa National Park, utilizing the “transect walk” method of Participatory Rural Appraisal (PRA). The data was analyzed using the following techniques: frequency of citation and informant consensus factor (Fic). The present communication gives information on 86 species belonging to 38 families of plants used by Tharu tribes of Dudhwa National Park, Uttar Pradesh. The frequency of citation was very high for Alstonia scholaris (fire-wood), Antidesma acidum, Artocarpus lakoocha (edible), Bauhinia vahlii, Butea monosperma (food plate), Dendrocalamus strictus (hut preparation), Hibiscus cannabinus (rope), Oryza rufipogon (food), Phoenix acaulis(edible) and Tamarix dioica (broom).