Gandhi Institute of Technology and Management

About: Gandhi Institute of Technology and Management is a education organization based out in Visakhapatnam, Andhra Pradesh, India. It is known for research contribution in the topics: Computer science & Heat transfer. The organization has 3392 authors who have published 4043 publications receiving 29139 citations. The organization is also known as: GITAM & GITAM College.

Sleep Disorders Associated With Alzheimer's Disease: A Perspective.

Abstract: Sleep disturbances, as well as sleep-wake rhythm disturbances, are typical symptoms of Alzheimer's disease (AD) that may precede the other clinical signs of this neurodegenerative disease. Here, we describe clinical features of sleep disorders in AD and the relation between sleep disorders and both cognitive impairment and poor prognosis of the disease. There are difficulties of the diagnosis of sleep disorders based on sleep questionnaires, polysomnography or actigraphy in the AD patients. Typical disturbances of the neurophysiological sleep architecture in the course of the AD include deep sleep and paradoxical sleep deprivation. Among sleep disorders occurring in patients with AD, the most frequent disorders are sleep breathing disorders and restless legs syndrome. Sleep disorders may influence circadian fluctuations of the concentrations of amyloid-β in the interstitial brain fluid and in the cerebrovascular fluid related to the glymphatic brain system and production of the amyloid-β. There is accumulating evidence suggesting that disordered sleep contributes to cognitive decline and the development of AD pathology. In this mini-review, we highlight and discuss the association between sleep disorders and AD.

Growth and insect assays of Beauveria bassiana with neem to test their compatibility and synergism

Abstract: Beauveria bassiana is being used as a biopesticide for many insect pests. Neem oil (azadirachtin) is an eco-safe popular botanical pesticide. A biopesticde with a neem compatible isolate of B. bassiana will enable their simultaneous use in pest management. A sample of 30 isolates of B. bassiana from culture collections was screened for compatibility with a commercial formulation of neem oil (Margoside®) at the field recommended dose (0.3%, v/v). Compatibility was tested in vitro through germination and growth assays. In all isolates, conidial germination was delayed but not significantly decreased by neem. In the growth assays, 23 isolates were found compatible with neem. In the neem sensitive isolates, growth was decreased but not totally inhibited. The effect of combined treatment with B. bassiana and neem in comparison to single treatments with either of them on Spodoptera litura Fabricius was tested in laboratory bioassays. The combined treatment was found to have synergistic effect on insect...

Applicability of cutting fluids with nanoparticle inclusion as coolants in machining

Abstract: Heat liberated and the friction associated with the cutting process ever pose a problem in terms of tool life. Cutting fluids have been the conventional choice to address the problem. Howev...

The influence of solid lubricant particle size on machining parameters in turning

Abstract: Turning is one of the most fundamental and indispensable processes of metal removal in industry. The heat generated in the cutting zone during turning is critical in deciding the workpiece quality and tool life. Though cutting fluids are widely employed to carry away the heat in metal cutting, their usage poses threat to ecology and the health of workers. Hence, there arises a need to identify eco-friendly and user-friendly alternatives to conventional cutting fluids. Modern tribology has facilitated the use of solid lubricants. The present work features a specific study of the application of solid lubricant in turning. The process performance is judged in terms of cutting force, tool temperature, tool wear and the surface finish of workpiece, keeping the cutting conditions constant. The results obtained from the experiment show the effectiveness of the use of the solid lubricant as a viable alternative to dry and wet machining. The unique utility of solid lubricant is highlighted.