Gandhi Institute of Technology and Management

About: Gandhi Institute of Technology and Management is a education organization based out in Visakhapatnam, Andhra Pradesh, India. It is known for research contribution in the topics: Computer science & Heat transfer. The organization has 3392 authors who have published 4043 publications receiving 29139 citations. The organization is also known as: GITAM & GITAM College.

Does Involving Additional Linker Always Increase the Efficiency of an Organic Dye for p-Type Dye-Sensitized Solar Cells?

Abstract: A series of different simple and fused conjugated structures as additional spacers for dyes with triphenylamine and cyanoacrylic acid as the donor and acceptor units have been designed and investig...

Regulatory role of sphingosine kinase and sphingosine-1-phosphate receptor signaling in progenitor/stem cells

Abstract: Balanced sphingolipid signaling is important for the maintenance of homeostasis. Sphingolipids were demonstrated to function as structural components, second messengers, and regulators of cell growth and survival in normal and disease-affected tissues. Particularly, sphingosine kinase 1 (SphK1) and its product sphingosine-1-phosphate (S1P) operate as mediators and facilitators of proliferation-linked signaling. Unlimited proliferation (self-renewal) within the regulated environment is a hallmark of progenitor/stem cells that was recently associated with the S1P signaling network in vasculature, nervous, muscular, and immune systems. S1P was shown to regulate progenitor-related characteristics in normal and cancer stem cells (CSCs) via G-protein coupled receptors S1Pn (n = 1 to 5). The SphK/S1P axis is crucially involved in the regulation of embryonic development of vasculature and the nervous system, hematopoietic stem cell migration, regeneration of skeletal muscle, and development of multiple sclerosis. The ratio of the S1P receptor expression, localization, and specific S1P receptor-activated downstream effectors influenced the rate of self-renewal and should be further explored as regeneration-related targets. Considering malignant transformation, it is essential to control the level of self-renewal capacity. Proliferation of the progenitor cell should be synchronized with differentiation to provide healthy lifelong function of blood, immune systems, and replacement of damaged or dead cells. The differentiation-related role of SphK/S1P remains poorly assessed. A few pioneering investigations explored pharmacological tools that target sphingolipid signaling and can potentially confine and direct self-renewal towards normal differentiation. Further investigation is required to test the role of the SphK/S1P axis in regulation of self-renewal and differentiation.

DC electrical conductivity, thermoelectric power measurements of TiO2-substituted lead vanadate glasses

Abstract: Glasses of the system x(TiO2)(50−x)PbO:50V2O5 were prepared by melt-quench process in the range x=0–15 mole%. Measurements are reported for DC electrical conductivity as well as thermoelectrical power for the above compositions in the temperature range 27–227 °C. The experimental results are analyzed with reference to various theoretical models proposed for DC electrical conduction in amorphous semiconductors. The analysis shows that at high temperatures, the temperature dependence of DC conductivity is consistent with Mott's model of phonon-assisted hopping conduction, variable range hopping mechanism and Schnakenberg's model mechanism. The high-temperature thermoelectric power (TEP) was satisfactorily explained by Heikes’ relation and the data also showed evidence of small polaron formation in these glasses. Thermo EMF measurements indicate that all the glass samples including unsubstituted lead metavanadate are n-type at room temperature. As temperature is increased TiO2-substituted samples change from n-type to p-type. When Heike's formula is applied to all the systems at room temperature, the amount of disorder was found to be the same in all the systems. When Emin's formula is used for the estimation of WD, the activation energy due to disorder, in TiO2-substituted samples, unusually large values of WD (∼0.6 eV) are obtained. The present results indicate that the Emin's formula cannot be directly used to estimate the disorder energy in TiO2-substituted lead vanadates. The temperature-dependent change of sign of the TEP S, in these systems may arise due to change in V4+/V5+ ratio with the change of temperature or due to the onset of band type of conduction as in MnO or other extrinsic compensated semi-conductors.

Analysing the Adoption of Intelligent Agent Technology in Food Supply Chain Management: An Empirical Evidence:

Abstract: This article aims to identify and analyse the factors that impact the adoption of intelligent agent technology (IAT) in the food supply chain (FSC). The research was conducted based on 329 responde...

Modeling transient magnetohydrodynamic peristaltic pumping of electroconductive viscoelastic fluids through a deformable curved channel

Abstract: A mathematical model is presented to analyze the unsteady peristaltic flow of magnetized viscoelastic fluids through a deformable curved channel. The study simulates the bio-inspired pumping of electroconductive rheological polymers which possess both electroconductive and viscoelastic properties. The Jeffrey viscoelastic model is utilized which features both relaxation and retardation terms of relevance to real polymers. A magnetic body force is incorporated for the influence of static radial magnetic field. The mass and momentum conservation equations are formulated in an intrinsic coordinate system and transformed with appropriate variables into a nondimensional system between the wave and the laboratory frames, under lubrication (i.e., low Reynolds number and long wavelength) approximations. Kinematic and no-slip boundary conditions are imposed at the channel walls. A magnetic body force is incorporated for the influence of static radial magnetic field in the primary momentum equation. An analytic approach is employed to determine closed-form solutions for stream function, axial pressure gradient, and volumetric flow rate. Spatiotemporal plots for pressure distribution along the channel (passage) length are presented to study the influences of curvature parameter, relaxation-to-retardation time ratio (Jeffrey first viscoelastic parameter) and Hartmann number (magnetic field parameter). The effects of these parameters on radial velocity distributions are also visualized. Cases of trapping and reflux in a curved channel are discussed. Streamline distributions are included to study trapping phenomena and to investigate more closely the impact of curvature, magnetic field, and viscoelastic properties on bolus evolution. The reflux or retrograde motion of the particles is studied by particle advection based on Lagrangian viewpoint. The simulations provide new insight into the mechanisms of pumping of electroconductive non-Newtonian liquids in realistic geometries.